Prevalence and characteristics of rmtB and qepA in Escherichia coli isolated from diseased animals in China

Frontiers in Microbiology

Volumn 4, Issue JUL, 2013, Pages

  Deng, Yu Ting ^a,b   Zeng, Zhen Ling ^a   Tian, Wei ^a   Yang, Tong ^a   Liu, Jian Hua ^a  

^a SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^b SOUTH CHINA SEA FISHERIES RESEARCH INSTITUTE   (China)

Author keywords

16S rRNA methylases; Animal; E. coli; Molecular typing; Qepa

Indexed keywords

AMIKACIN; AMPICILLIN; APRAMYCIN; CEFTIOFUR; CHLORAMPHENICOL; CIPROFLOXACIN; COTRIMOXAZOLE; FLORFENICOL; GENTAMICIN; NALIDIXIC ACID; NEOMYCIN; NORFLOXACIN; RNA 16S; RNA METHYLTRANSFERASE; STREPTOMYCIN; TETRACYCLINE;

ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM CONJUGATION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CHINA; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR TYPING; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PREVALENCE; PULSED FIELD GEL ELECTROPHORESIS; QEPA GENE; RMTB GENE; SCREENING;

ANIMALIA; ARMA; ESCHERICHIA COLI;

EID: 84885364520     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2013.00198     Document Type: Article

References (39)

1. Baudry, P. J., Nichol, K., Decorby, M., Lagacé-Wiens, P., Olivier, E., Boyd, D., et al. (2009). Mechanisms of resistance and mobility among multidrug-resistant CTX-M-producing Escherichia coli from Canadian intensive care units: the 1st report of QepA in North America. Diagn. Microbiol. Infect. Dis. 63, 319-326. doi: 10.1016/j.diagmicrobio.2008.12.001
2. Berçot, B., Poirel, L., and Nordmann, P. (2008). Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. Antimicrob. Agents Chemother. 52, 4526-4527. doi: 10.1128/AAC.00882-08
3. Bogaerts, P., Galimand, M., Bauraing, C., Deplano, A., Vanhoof, R., De Mendonca, R., et al. (2007). Emergence of ArmA and RmtB aminoglycoside resistance 16S rRNA methylases in Belgium. J. Antimicrob. Chemother. 59, 459-464. doi: 10.1093/jac/dkl527
4. Bueno, M. F., Francisco, G. R., O'Hara, J. A., de Oliveira Garcia, D., and Doi, Y. (2013). Co-production of 16S ribosomal RNA methyltransferase RmtD and RmtG with KPC-2 and CTX-M-group ESBLs in Klebsiella pneumoniae. Antimicrob. Agents Chemother. 53, 2397-2400. doi: 10.1128/AAC.02108-12
5. Cattoir, V., Poirel, L., and Nordmann, P. (2008). Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. Antimicrob. Agents Chemother. 52, 3801-3804. doi: 10.1128/AAC.00638-08
6. Chen, L., Chen, Z. L., Liu, J. H., Zeng, Z. L., Ma, J. Y., and Jiang, H. X. (2007). Emergence of RmtB methylase-producing Escherichia coli and Enterobacter cloacae isolates from pigs in China. J. Antimicrob. Chemother. 59, 880-885. doi: 10.1093/jac/dkm065
7. Clermont, O., Bonacorsi, S., and Bingen, E. (2000). Rapid and simple determination of the Escherichia coli phylogenetic group. Appl. Environ. Microbiol. 66, 4555-4558. doi: 10.1128/AEM.66.10.4555-4558.2000
8. Clinical Laboratory Standard Institute (CLSI). (2008). "Performance standards for antimicrobial disk suseptibility tests for bacteria isolated from animals; approved standard," in Third Edition Document M31-A3 (Wayne, PA: CLSI).
9. Clinical Laboratory Standard Institute. (CLSI). (2010). "Performance standards for antimicrobial suseptibility testing," in Twentieth Informational Supplement M100-S20 (Wayne, PA: CLSI).
10. Davis, M. A., Baker, K. N., Orfe, L. H., Shah, D. H., Besser, T. E., and Call, D. R. (2010). Discovery of a gene conferring multiple-aminoglycoside resistance in Escherichia coli. Antimicrob. Agents Chemother. 54, 2666-2669. doi: 10.1128/AAC.01743-09
11. Deng, Y., He, L., Chen, S., Zheng, H., Zeng, Z., Liu, Y., et al. (2011a). F33:A-:B- and F2:A-:B- plasmids mediate dissemination of rmtB-blaCTX-M-9 group genes and rmtB-qepA in Enterobacteriaceae isolates from pets in China. Antimicrob. Agents Chemother. 55, 4926-4929. doi: 10.1128/AAC.00133-11
12. Deng, Y., Zeng, Z., Chen, S., He, L., Liu, Y., Wu, C., et al. (2011b). Dissemination of IncFII plasmids carrying rmtB and qepA in Escherichia coli from pigs, farm workers and the environment. Clin. Microbiol. Infect. 17, 1740-1745. doi: 10.1111/j.1469-0691.2011.03472.x
13. Doi, Y., and Arakawa, Y. (2007). 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin. Infect. Dis. 45, 88-94. doi: 10.1086/518605
14. Du, X. D., Wu, C. M., Liu, H. B., Li, X. S., Beier, R. C., Xiao, F., et al. (2009). Plasmid-mediated ArmA and RmtB 16S rRNA methylases in Escherichia coli isolated from chickens. J. Antimicrob. Chemother. 64, 1328-1330. doi: 10.1093/jac/dkp354
15. Fritsche, T. R., Castanheira, M., Miller, G. H., Jones, R. N., and Armstrong, E. S. (2008). Detection of methyltransferases conferring high-level resistance to aminoglycosides in Enterobacteriaceae from Europe, North America, and Latin America. Antimicrob. Agents Chemother. 52, 1843-1845. doi: 10.1128/AAC.01477-07
16. Galimand, M., Courvalin, P., and Lambert, T. (2003). Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob. Agents Chemother. 47, 2565-2571. doi: 10.1128/AAC.47.8.2565-2571.2003
17. Galimand, M., Courvalin, P., and Lambert, T. (2012). RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family. Antimicrob. Agents Chemother. 56, 3960-3962. doi: 10.1128/AAC.00660-12
18. González-Zorn, B., Teshager, T., Casas, M., Porrero, M. C., Moreno, M. A., Courvalin, P., et al. (2005). armA and aminoglycoside resistance in Escherichia coli. Emerg. Infect. Dis. 11, 954-956. doi: 10.3201/eid1106.040553
19. Hopkins, K. L., Escudero, J. A., Hidalgo, L., and Gonzalez-Zorn, B. (2010). 16S rRNA methyltransferase RmtC in Salmonella enterica serovar Virchow. Emerg. Infect. Dis. 16, 712-715. doi: 10.3201/eid1604.090736
20. Kang, H. Y., Kim, J., Seol, S. Y., Lee, Y. C., Lee, J. C., and Cho, D. T. (2009). Characterization of conjugative plasmids carrying antibiotic resistance genes encoding 16S rRNA methylase, extended-spectrum beta-lactamase, and/or plasmid-mediated AmpC beta-lactamase. J. Microbiol. 47, 68-75. doi: 10.1007/s12275-008-0158-3
21. Kang, H. Y., Kim, K. Y., Kim, J., Lee, J. C., Lee, Y. C., Cho, D. T., et al. (2008). Distribution of conjugative-plasmid-mediated 16S rRNA methylase genes among amikacin-resistant Enterobacteriaceae isolates collected in 1995 to 1998 and 2001 to 2006 at a university hospital in South Korea and identification of conjugative plasmids mediating dissemination of 16S rRNA methylase. J. Clin. Microbiol. 46, 700-706. doi: 10.1128/JCM.01677-07
22. Kim, E. S., Jeong, J. Y., Choi, S. H., Lee, S. O., Kim, S. H., Kim, M. N., et al. (2009). Plasmid-mediated fluoroquinolone efflux pump gene, qepA, in Escherichia coli clinical isolates in Korea. Diagn. Microbiol. Infect. Dis. 65, 335-338. doi: 10.1016/j.diagmicrobio.2009.07.006
23. Kim, J., Bae, I. K., Jeong, S. H., Chang, C. L., Lee, C. H., and Lee, K. (2011). Characterization of IncF plasmids carrying the blaCTX-M-14 gene in clinical isolates of Escherichia coli from Korea. J. Antimicrob. Chemother. 66, 1263-1268. doi: 10.1093/jac/dkr106
24. Lee, H., Yong, D., Yum, J. H., Roh, K. H., Lee, K., Yamane, K., et al. (2006). Dissemination of 16S rRNA methylase-mediated highly amikacin-resistant isolates of Klebsiella pneumoniae and Acinetobacter baumannii in Korea. Diagn. Microbiol. Infect. Dis. 56, 305-312. doi: 10.1016/j.diagmicrobio.2006.05.002
25. Li, D. X., Zhang, S. M., Hu, G. Z., Wang, Y., Liu, H. B., Wu, C. M., et al. (2012). Tn3-associated rmtB together with qnrS1, aac(6')-Ib-cr and blaCTX-M-15 are co-located on an F49:A-:B- plasmid in an Escherichia coli ST10 strain in China. J. Antimicrob. Chemother. 67, 236-238. doi: 10.1093/jac/dkr428
26. Liu, J. H., Deng, Y. T., Zeng, Z. L., Gao, J. H., Chen, L., Arakawa, Y., et al. (2008). Coprevalence of plasmid-mediated quinolone resistance determinants QepA, Qnr, and AAC(6')-Ib-cr among 16S rRNA methylase RmtB-producing Escherichia coli isolates from pigs. Antimicrob. Agents Chemother. 52, 2992-2993. doi: 10.1128/AAC.01686-07
27. O'Hara, J. A., McGann, P., Snesrud, E. C., Clifford, R. J., Waterman, P. E., Lesho, E. P., et al. (2013). Novel 16S ribosomal RNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma. Antimicrob. Agents Chemother. 57, 2413-2416. doi: 10.1128/AAC.00266-13
28. Park, Y. J., Yu, J. K., Kim, S. I., Lee, K., and Arakawa, Y. (2009). Accumulation of plasmid-mediated fluoroquinolone resistance genes, qepA and qnrS1, in Enterobacter aerogenes co-producing RmtB and class A beta-lactamase LAP-1. Ann. Clin. Lab. Sci. 39, 55-59.
29. Périchon, B., Bogaerts, P., Lambert, T., Frangeul, L., Courvalin, P., and Galimand, M. (2008). Sequence of conjugative plasmid pIP1206 mediating resistance to aminoglycosides by 16S rRNA methylation and to hydrophilic fluoroquinolones by efflux. Antimicrob. Agents Chemother. 52, 2581-2592. doi: 10.1128/AAC.01540-07
30. Périchon, B., Courvalin, P., and Galimand, M. (2007). Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli. Antimicrob. Agents Chemother. 51, 2464-2469. doi: 10.1128/AAC.00143-07
31. Song, S., Lee, E. Y., Koh, E. M., Ha, H. S., Jeong, H. J., Bae, I. K., et al. (2009). Antibiotic resistance mechanisms of Escherichia coli isolates from urinary specimens. Korean J. Lab. Med. 29, 17-24. doi: 10.3343/kjlm.2009.29.1.17
32. Tenover, F. C., Arbeit, R. D., Goering, R. V., Mickelsen, P. A., Murray, B. E., Persing, D. H., et al. (1995). Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33, 2233-2239.
33. Wachino, J., Shibayama, K., Kurokawa, H., Kimura, K., Yamane, K., Suzuki, S., et al. (2007). Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. Antimicrob. Agents Chemother. 51, 4401-4409. doi: 10.1128/AAC.00926-07
34. Yamane, K., Wachino, J., Suzuki, S., and Arakawa, Y. (2008). Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob. Agents Chemother. 52, 1564-1566. doi: 10.1128/AAC.01137-07
35. Yamane, K., Wachino, J., Suzuki, S., Kimura, K., Shibata, N., Kato, H., et al. (2007). New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrob. Agents Chemother. 51, 3354-3360. doi: 10.1128/AAC.00339-07
36. Yan, J. J., Wu, J. J., Ko, W. C., Tsai, S. H., Chuang, C. L., Wu, H. M., et al. (2004). Plasmid-mediated 16S rRNA methylases conferring high-level aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae isolates from two Taiwanese hospitals. J. Antimicrob. Chemother. 54, 1007-1012. doi: 10.1093/jac/dkh455
37. Yao, Q., Zeng, Z., Hou, J., Deng, Y., He, L., Tian, W., et al. (2011). Dissemination of the rmtB gene carried on IncF and IncN plasmids among Enterobacteriaceae in a pig farm and its environment. J. Antimicrob. Chemother. 66, 2475-2479. doi: 10.1093/jac/dkr328
38. Yokoyama, K., Doi, Y., Yamane, K., Kurokawa, H., Shibata, N., Shibayama, K., et al. (2003). Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa. Lancet 362, 1888-1893. doi: 10.1016/S0140-6736(03)14959-8
39. Yu, F. Y., Yao, D., Pan, J. Y., Chen, C., Qin, Z. Q., Parsons, C., et al. (2010). High prevalence of plasmid-mediated 16S rRNA methylase gene rmtB among Escherichia coli clinical isolates from a Chinese teaching hospital. BMC Infect. Dis. 10:184. doi: 10.1186/1471-2334-10-184