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Volumn 6, Issue 10, 2013, Pages 2112-2120

Clinicopathological significance of PTEN and PI3K/AKT signal transduction pathway in non-small cell lung cancer

Author keywords

EGFR; Non small cell lung cancer (NSCLC); P AKT; PTEN; TGF

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PTEN PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 84885356763     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (23)

References (26)
  • 1
    • 84878606415 scopus 로고    scopus 로고
    • Lung cancer chemoprevention: current status and future prospects.
    • Nat Rev Clin Oncol
    • Keith RL, Miller YE. Lung cancer chemoprevention: current status and future prospects. Nat Rev Clin Oncol 2013; 10: 334-43.
    • (2013) , vol.10
    • Keith, R.L.1    Miller, Y.E.2
  • 2
    • 84862615114 scopus 로고    scopus 로고
    • II. Field cancerization in non-small cell lung cancer: implications in disease pathogenesis.
    • Proc Am Thorac Soc
    • Kadara H, Wistuba II. Field cancerization in non-small cell lung cancer: implications in disease pathogenesis. Proc Am Thorac Soc 2012; 9: 38-42.
    • (2012) , vol.9 , pp. 38-42
    • Kadara, H.1    Wistuba, I.I.2
  • 3
    • 84946234164 scopus 로고    scopus 로고
    • PI3K Pathway in Gynecologic Malignancies.
    • Am Soc Clin Oncol Educ Book 2013;
    • Salvesen HB, Werner HM, Krakstad C. PI3K Pathway in Gynecologic Malignancies. Am Soc Clin Oncol Educ Book 2013; 2013: 218-21.
    • (2013) , pp. 218-221
    • Salvesen, H.B.1    Werner, H.M.2    Krakstad, C.3
  • 6
    • 84879029656 scopus 로고    scopus 로고
    • PTEN, Akt, MAPK, p53 and p95 expression to predict trastuzumab resistance in HER2 positive breast cancer. J BUON
    • Duman BB, Sahin B, Acikalin A, Ergin M, Zorludemir S. PTEN, Akt, MAPK, p53 and p95 expression to predict trastuzumab resistance in HER2 positive breast cancer. J BUON 2013; 18: 44-50.
    • (2013) , vol.18 , pp. 44-50
    • Duman, B.B.1    Sahin, B.2    Acikalin, A.3    Ergin, M.4    Zorludemir, S.5
  • 7
    • 84873171934 scopus 로고    scopus 로고
    • Primary lung adenocarcinoma occurring in a PTEN related syndrome (Cowden's disease): routine EGFR sequencing also highlights two rare somatic mutations S768I and V769L. Lung Cancer
    • Boespflug A, Couraud S, Bringuier PP, Isaac S, Gérinière L, Perrot E, Edery P, Durieu I, Souquet PJ. Primary lung adenocarcinoma occurring in a PTEN related syndrome (Cowden's disease): routine EGFR sequencing also highlights two rare somatic mutations S768I and V769L. Lung Cancer 2013; 79: 318-20.
    • (2013) , vol.79 , pp. 318-320
    • Boespflug, A.1    Couraud, S.2    Bringuier, P.P.3    Isaac, S.4    Gérinière, L.5    Perrot, E.6    Edery, P.7    Durieu, I.8    Souquet, P.J.9
  • 8
    • 84870426774 scopus 로고    scopus 로고
    • Clinicopathological significance of PTEN and bcl2 expressions in oral squamous cell carcinoma. Int J Clin Exp Pathol
    • Rahmani A, Alzohairy M, Babiker AY, Rizvi MA, Elkarimahmad HG. Clinicopathological significance of PTEN and bcl2 expressions in oral squamous cell carcinoma. Int J Clin Exp Pathol 2012; 5: 965-71.
    • (2012) , vol.5 , pp. 965-971
    • Rahmani, A.1    Alzohairy, M.2    Babiker, A.Y.3    Rizvi, M.A.4    Elkarimahmad, H.G.5
  • 9
    • 84867007195 scopus 로고    scopus 로고
    • The prognostic value of the immunohistochemical aspects of tumor suppressor genes p53, bcl-2, PTEN and nuclear proliferative antigen Ki-67 in resected colorectal carcinoma. Rom J Morphol Embryol
    • Ghita C, Vîlcea ID, Dumitrescu M, Vîlcea AM, Mirea CS, Aschie M, Vasilescu F. The prognostic value of the immunohistochemical aspects of tumor suppressor genes p53, bcl-2, PTEN and nuclear proliferative antigen Ki-67 in resected colorectal carcinoma. Rom J Morphol Embryol 2012; 53: 549-56.
    • (2012) , vol.53 , pp. 549-556
    • Ghita, C.1    Vîlcea, I.D.2    Dumitrescu, M.3    Vîlcea, A.M.4    Mirea, C.S.5    Aschie, M.6    Vasilescu, F.7
  • 10
    • 84885341275 scopus 로고    scopus 로고
    • Effects of indomethacin on expression of PTEN tumour suppressor in human cancers.
    • Niger Med J
    • Abdulkareem IH, Blair M. Effects of indomethacin on expression of PTEN tumour suppressor in human cancers. Niger Med J 2013; 54: 100-6.
    • (2013) , vol.54 , pp. 100-106
    • Abdulkareem, I.H.1    Blair, M.2
  • 13
    • 79960889850 scopus 로고    scopus 로고
    • Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells. Lung Cancer
    • Akca H, Demiray A, Tokgun O, Yokota J. Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells. Lung Cancer 2011; 73: 302-9.
    • (2011) , vol.73 , pp. 302-309
    • Akca, H.1    Demiray, A.2    Tokgun, O.3    Yokota, J.4
  • 14
    • 84880223571 scopus 로고    scopus 로고
    • Control of oncogenesis by eIF2a phosphorylation: implications in PTEN and PI3K-Akt signaling and tumor treatment. Future Oncol
    • Koromilas AE, Mounir Z. Control of oncogenesis by eIF2a phosphorylation: implications in PTEN and PI3K-Akt signaling and tumor treatment. Future Oncol 2013; 9: 1005-15.
    • (2013) , vol.9 , pp. 1005-1015
    • Koromilas, A.E.1    Mounir, Z.2
  • 17
    • 84874180366 scopus 로고    scopus 로고
    • EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: implications for targeted therapy. Discov Med
    • Berg M, Soreide K. EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: implications for targeted therapy. Discov Med 2012; 14: 207-14.
    • (2012) , vol.14 , pp. 207-214
    • Berg, M.1    Soreide, K.2
  • 20
    • 84876475518 scopus 로고    scopus 로고
    • Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome. Hum Pathol
    • Bettstetter M, Berezowska S, Keller G, Walch A, Feuchtinger A, Slotta-Huspenina J, Feith M, Drecoll E, Höfler H, Langer R. Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome. Hum Pathol 2013; 44: 829-36.
    • (2013) , vol.44 , pp. 829-836
    • Bettstetter, M.1    Berezowska, S.2    Keller, G.3    Walch, A.4    Feuchtinger, A.5    Slotta-Huspenina, J.6    Feith, M.7    Drecoll, E.8    Höfler, H.9    Langer, R.10
  • 23
    • 32844474579 scopus 로고    scopus 로고
    • Potential prognostic significance of p18-5(HER2) overexpression with loss of PTEN expression in gastric carcinomas. Tumori
    • Im SA, Lee KE, Nam E, Kim DY, Lee JH, Han HS, Seoh JY, Park HY, Cho MS, Han WS, Lee SN. Potential prognostic significance of p18-5(HER2) overexpression with loss of PTEN expression in gastric carcinomas. Tumori 2005; 91: 513-21.
    • (2005) , vol.91 , pp. 513-521
    • Im, S.A.1    Lee, K.E.2    Nam, E.3    Kim, D.Y.4    Lee, J.H.5    Han, H.S.6    Seoh, J.Y.7    Park, H.Y.8    Cho, M.S.9    Han, W.S.10    Lee, S.N.11
  • 25
    • 84876219974 scopus 로고    scopus 로고
    • mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy. J Cell Biochem
    • Kim EJ, Jeong JH, Bae S, Kang S, Kim CH, Lim YB. mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy. J Cell Biochem 2013; 114: 1248-56.
    • (2013) , vol.114 , pp. 1248-1256
    • Kim, E.J.1    Jeong, J.H.2    Bae, S.3    Kang, S.4    Kim, C.H.5    Lim, Y.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.