Of timescales, animal models, and human disease: The 50th anniversary of C. elegans as a biological model

Frontiers in Neurology

Volumn 4 OCT, Issue , 2013, Pages

  Agoston, Denes V ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Animal; Clinical studies; Disease models; Inflammation; Nervous system; Translational research; Trauma

Indexed keywords

APOPTOSIS; BLAST INJURY; BURN; CAENORHABDITIS ELEGANS; CELL FATE; DEVELOPMENTAL STAGE; ENDOTOXEMIA; EXPERIMENTAL MODEL; EXPERIMENTAL STUDY; HUMAN; INJURY; LIFE CYCLE; MEDICAL RESEARCH; MOLECULAR BIOLOGY; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NOTE; RNA INTERFERENCE; SPECIES DIFFERENCE; TRANSLATIONAL RESEARCH; TRAUMATIC BRAIN INJURY;

EID: 84885350217     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2013.00129     Document Type: Note

References (5)

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3. Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 110:3507-12. doi:10.1073/pnas.1222878110.
4. Agoston DV, Risling M. Where will the (new) drugs for traumatic brain injury treatment be coming from? Front Neurol (2012) 3:27. doi:10.3389/fneur.2012.00107.
5. Agoston DV, Risling M, Bellander BM. Bench-to-bedside and bedside back to the bench; coordinating clinical and experimental traumatic brain injury studies. Front Neurol (2012) 3:3. doi:10.3389/fneur.2012.00003.