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Volumn 3, Issue 9, 2013, Pages

Activation of Jak2 in patients with blast crisis chronic myelogenous leukemia: Inhibition of Jak2 inactivates Lyn kinase

Author keywords

[No Author keywords available]

Indexed keywords

IMATINIB; JANUS KINASE 2; N TERT BUTYL 3 [5 METHYL 2 [4 (4 METHYL 1 PIPERAZINYL)PHENYLAMINO] 4 PYRIMIDINYLAMINO]BENZENESULFONAMIDE; PROTEIN KINASE LYN;

EID: 84885335227     PISSN: None     EISSN: 20445385     Source Type: Journal    
DOI: 10.1038/bcj.2013.41     Document Type: Letter
Times cited : (9)

References (6)
  • 1
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    • DOI 10.1126/science.1062538
    • Gorre ME, Mohammed M, Ellwood K, Hsu N, Paquette R, Rao PN et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293: 876-880. (Pubitemid 32743979)
    • (2001) Science , vol.293 , Issue.5531 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Nagesh Rao, P.6    Sawyers, C.L.7
  • 3
    • 9144223047 scopus 로고    scopus 로고
    • Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells
    • DOI 10.1038/nm1127
    • Ptasznik A, Nakata Y, Kalota A, Emerson SG, Gewirtz AM. Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells. Nat Med 2004; 10: 1187-1189. (Pubitemid 39540433)
    • (2004) Nature Medicine , vol.10 , Issue.11 , pp. 1187-1189
    • Ptasznik, A.1    Nakata, Y.2    Kalota, A.3    Emerson, S.G.4    Gewirtz, A.M.5
  • 4
    • 79952437988 scopus 로고    scopus 로고
    • Janus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia
    • Samanta A, Perazzona B, Chakraborty S, Sun X, Modi H, Bhatia R et al. Janus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia. Leukemia 2011; 25: 463-472.
    • (2011) Leukemia , Issue.25 , pp. 463-472
    • Samanta, A.1    Perazzona, B.2    Chakraborty, S.3    Sun, X.4    Modi, H.5    Bhatia, R.6
  • 5
    • 64949147229 scopus 로고    scopus 로고
    • Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients
    • Samanta AK, Chakraborty S, Wang Y, Kantarjian H, Sun X, Hood J et al. Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients. Oncogene 2009; 28: 1669-1681.
    • (2009) Oncogene , vol.28 , pp. 1669-1681
    • Samanta, A.K.1    Chakraborty, S.2    Wang, Y.3    Kantarjian, H.4    Sun, X.5    Hood, J.6
  • 6
    • 33746139407 scopus 로고    scopus 로고
    • Janus kinase 2: A critical target in chronic myelogenous leukemia
    • DOI 10.1158/0008-5472.CAN-06-0025
    • Samanta AK, Lin H, Sun T, Kantarjian H, Arlinghaus RB. Janus kinase 2: a critical target in chronic myelogenous leukemia. Cancer Res 2006; 66: 6468-6472. (Pubitemid 44085597)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6468-6472
    • Samanta, A.K.1    Lin, H.2    Sun, T.3    Kantarjian, H.4    Arlinghaus, R.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.