Histone deacetylase inhibitor AR-42 enhances E7-specific CD8+ T cell-mediated antitumor immunity induced by therapeutic HPV DNA vaccination

Journal of Molecular Medicine

Volumn 91, Issue 10, 2013, Pages 1221-1231

  Lee, Sung Yong ^a,b   Huang, Zhuomin ^a,c   Kang, Tae Heung ^a,d   Soong, Ruey Shyang ^a,e,f   Knoff, Jayne ^a   Axenfeld, Ellen ^a   Wang, Chenguang ^g   Alvarez, Ronald D ^h   Chen, Ching Shih ⁱ   Hung, Chien Fu ^a   Wu, T C ^a,j  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b Korea University Ansan Hospital   (South Korea)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

^d Konkuk University   (South Korea)

^e CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^f CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^g JOHNS HOPKINS UNIVERSITY   (United States)

^h UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

ⁱ OHIO STATE UNIVERSITY   (United States)

^j JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Cancer vaccine; Cervical cancer; Histone deacetylase inhibitor; Human papillomavirus

Indexed keywords

ANTINEOPLASTIC AGENT; AR 42; CALRETICULIN; DNA VACCINE; HISTONE DEACETYLASE INHIBITOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN E7; ROMIDEPSIN; UNCLASSIFIED DRUG; WART VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SUSCEPTIBILITY; CANCER THERAPY; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXICITY; DNA IMMUNIZATION; FEMALE; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNE RESPONSE; IN VIVO STUDY; MOUSE; NONHUMAN; TUMOR GROWTH; TUMOR IMMUNITY; UTERINE CERVIX CANCER; WART VIRUS;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CELL MEMBRANE; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTONE DEACETYLASE INHIBITORS; HUMANS; MICE; NEOPLASMS; PAPILLOMAVIRUS E7 PROTEINS; PAPILLOMAVIRUS VACCINES; TRANSFECTION; TUMOR BURDEN; VACCINES, DNA;

EID: 84885329272     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-013-1054-9     Document Type: Article

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