Blood manganese concentration is elevated in infants with iron deficiency

Biological Trace Element Research

Volumn 155, Issue 2, 2013, Pages 184-189

  Park, Sangkyu ^a   Sim, Chang Sun ^b   Lee, Heun ^b   Kim, Yangho ^b  

^a Ulsan University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Anemia; Deficiency; Iron; Manganese

Indexed keywords

FERRITIN; HEMOGLOBIN; IRON; IRON POLYMALTOSE; MANGANESE;

ABSORPTION; ARTICLE; BLOOD CELL COUNT; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; ETHNIC GROUP; FEMALE; FERRITIN BLOOD LEVEL; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HUMAN; INFANT; IRON BINDING CAPACITY; IRON BLOOD LEVEL; IRON DEFICIENCY; IRON THERAPY; KOREAN; MALE; MANGANESE BLOOD LEVEL; PRESCHOOL CHILD; TREATMENT DURATION; BLOOD; IRON DEFICIENCY ANEMIA;

ANEMIA, IRON-DEFICIENCY; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; MANGANESE;

EID: 84885321061     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-013-9782-9     Document Type: Article

References (48)

1. Lucchini RG, Kim Y (2009) Health effects of manganese. In: Vojtisek M, Prakash R (eds) Metals and neurotoxicity. Society for Science and Environment, India, pp 119-147
2. Freeland-Graves C, Lanes C (1994) Models to study manganese deficiency. In: Klimis-Tavantzis D (ed) Manganese in health and disease. CRC Press, Boca Raton, pp 59-86
3. Hurley LS, Keen CL (1987) Manganese. In: Underwood E, Mertz W (eds) Trace elements in human health and animal nutrition. Academic Press, New York, pp 185-223
4. Sarić M, Lucchini R (2007) Manganese. In: Nordberg GF (ed) Handbook on the toxicology of metals, 3rd edn. Elsevier, Amsterdam, pp 645-674
5. Barbeau A, Inoue N, Cloutier T (1976) Role of manganese in dystonia. Adv Neurol 14:339-352
6. Calne DB, Chu NS, Huang CC, Lu CS, Olanow W (1994) Manganism and idiopathic Parkinson's disease: similarities and differences. Neurology 44:1583-1586
7. Olanow CW (2004) Mn-induced parkinsonism and Parkinson's disease. Ann N Y Acad Sci 1012:209-223
8. Kim Y, Kim JW (2012) Toxic encephalopathy. Saf Health Work 3:243-256
9. Karki P, Lee E, Aschner M (2013) Manganese neurotoxicity: a focus on glutamate transporters. Ann Occup Environ Med 25:4
10. Bellinger DC (2013) Prenatal exposures to environmental chemicals and children's neurodevelopment: an update. Saf Health Work 4:1-11
11. Claus Henn B, Ettinger AS, Schwartz J, Téllez-Rojo MM, Lamadrid-Figueroa H, Hernández-Avila M et al (2010) Early postnatal blood manganese levels and children's neurodevelopment. Epidemiology 21:433-439
12. Bouchard MF, Sauvé S, Barbeau B, Legrand M, Brodeur ME, Bouffard T et al (2011) Intellectual impairment in school-age children exposed to manganese from drinking water. Environ Health Perspect 119:138-143
13. Bouchard M, Laforest F, Vandelac L, Bellinger D, Mergler D (2007) Hair manganese and hyperactive behaviors: pilot study of school-age children exposed through tap water. Environ Health Perspect 115:122-127
14. Khan K, Factor-Litvak P, Wasserman GA, Liu X, Ahmed E, Parvez F et al (2011) Manganese exposure from drinking water and children's classroom behavior in Bangladesh. Environ Health Perspect 119:1501-1506
15. Hauser RA, Zesiewicz TA, Rosemurgy AS, Martinez C, Olanow CW (1994) Manganese intoxication and chronic liver failure. Ann Neurol 36:871-875
16. Butterworth RF, Spahr L, Fontaine S, Layrargues GP (1995) Manganese toxicity, dopaminergic dysfunction and hepatic encephalopathy. Metab Brain Dis 10:259-267
17. Park NH, Park JK, Choi Y, Yoo C-I, Lee CR, Lee H et al (2003) Whole blood manganese correlates with high signal intensities on T1-weighted MRI in patients with liver cirrhosis. Neurotoxicology 24:909-915
18. Davis CD, Wolf TL, Greger JL (1992) Varying levels of manganese and iron affect absorption and gut endogenous losses of manganese by rats. J Nutr 122:1300-1308
19. Finley JW (1999) Manganese absorption and retention by young women is associated with serum ferritin concentration. Am J Clin Nutr 70:37-43
20. Finley JW, Johnson PE, Johnson LK (1994) Sex affects manganese absorption and retention by humans from a diet adequate in manganese. Am J Clin Nutr 60:949-955
21. Chua AC, Morgan EH (1996) Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Biol Trace Elem Res 55:39-54
22. Kwik-Uribe CL, Gietzen D, German JB, Golub MS, Keen CL (2000) Chronic marginal iron intakes during early development in mice result in persistent changes in dopamine metabolism and myelin composition. J Nutr 130:2821-2830
23. Erikson KM, Shihabi ZK, Aschner JL, Aschner M (2002) Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations. Biol Trace Elem Res 87:143-156
24. Kim Y, Lee BK (2011) Iron deficiency increases blood manganese level in the Korean general population according to KNHANES 2008. Neurotoxicology 32:247-254
25. Boojar MM, Goodarzi F, Basedaghat MA (2002) Long-term follow-up of workplace and well water manganese effects on iron status indexes in manganese miners. Arch Environ Health 57:519-528
26. Brna P, Gordon K, Dooley JM, Price V (2011) Manganese toxicity in a child with iron deficiency and polycythemia. J Child Neurol 26:891-894
27. Sahni V, Léger Y, Panaro L, Allen M, Giffin S, Fury D, Hamm N (2007) Case report: a metabolic disorder presenting as pediatric manganism. Environ Health Perspect 115:1776-1779
28. Centers for Disease Control and Prevention (1998) Recommendations to prevent and control iron deficiency in the United States. MMWR 47(RR-3):5
29. Baldwin S, Deaker M, Maher W (1994) Low volume microwave digestion of marine biological tissues for the measurement of trace elements. Analyst 119:1701-1704
30. Baruthio F, Guillard O, Arnaud J, Pierre F, Zawislak R (1988) Determination of manganese in biological materials by electrothermal atomic absorption spectrometry, a review. Clin Chem 34:227-234
31. de Benoist B, McLean E, Egli I, Cogswell M (eds) (2008) Worldwide prevalence of anaemia. World Health Organization, Geneva
32. NHANES (2013) Key statistics from NHANES (data are for 2003-2006). http://www.cdc.gov/nchs/fastats/anemia.htm. Accessed 5 May 2013
33. Lonnerdal B (1994) Manganese nutrition of infants. In: Klimis-Tavantzis DJ (ed) Manganese in health and disease. CRC Press, Boca Raton, pp 175-191
34. Lonnerdal B, Keen CL, Bell JG, Sandstrom B (1987) Manganese uptake and retention: experimental animal and human studies. In: Kies C (ed) Nutritional bioavailability of manganese. ACS Symposium Series 354. American Chemical Society, Washington, pp 9-20
35. Conrad ME, Umbreit JN, Moore EG, Hainsworth LN, Porubcin M, Simovich MJ et al (2002) Separate pathways for cellular uptake of ferric and ferrous iron. Am J Physiol Gastrointest Liver Physiol 279:G767-G774
36. Garrick MD, Dolan KG (2002) An expression system for a transporter of iron and other metals. Methods Mol Biol 196:147-154
37. Zoller H, Koch RO, Theurl I, Obrist P, Pietrangelo P, Montosi G et al (2001) Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload. Gastroenterology 120:1412-1429
38. Kim Y, Park JK, Choi Y, Yoo C-I, Lee CR, Lee H et al (2005) Blood manganese concentration is elevated in iron deficiency anemia patients, whereas globus pallidus signal intensity is minimally affected. Neurotoxicology 26:107-111
39. Mena I, Horiuchi K, Burke K, Cotizias G (1969) Chronic manganese poisoning. Individual susceptibility and absorption of iron. Neurology 19:1000-1003
40. Meltzer HM, Brantsaeter AL, Borch-Iohnsen B, Ellingsen DG, Alexander J, Thomassen Y et al (2010) Low iron stores are related to higher blood concentrations of manganese, cobalt and cadmium in non-smoking, Norwegian women in the HUNT 2 study. Environ Res 110:497-504
41. ATSDR (2012) Toxicological profile for manganese. Agency for Toxic Substances & Disease Registry, Atlanta
42. Burguera JL, Burguera M, Alarcon OM (1992) Blood levels of zinc cobalt iron and manganese in children from Mérida, Venezuela. Trace Elem Med 9:194-197
43. Alarcon OM, Reinosa-Fuller JA, Silva T, Ramirez de Fernandez M, Gamboa J (1996) Manganese levels in serum of healthy Venezuelan infants living in Mérida. J Trace Elem Med Biol 10:210-213
44. Rukgauer M, Klein J, Kruse-Jarres JD (1997) Reference values for the trace elements copper, manganese, selenium, and zinc in the serum/plasma of children, adolescents, and adults. J Trace Elem Med Biol 11:92-98
45. Rice DC, Lincoln R, Martha J, Parker L, Pote K, Xing S et al (2010) Concentration of metals in blood of Maine children 1-6 years old. J Expo Sci Environ Epidemiol 20:634-643
46. Maguire JL, Salehi L, Birken CS, Carsley S, Mamdani M, Thorpe KE et al (2013) Association between total duration of breastfeeding and iron deficiency. Pediatrics 131(5):e1530-e1537
47. Dee DL, Sharma AJ, Cogswell ME, Grummer-Strawn LM, Fein SB, Scanlon KS (2008) Sources of supplemental iron among breastfed infants during the first year of life. Pediatrics 122(Suppl 2):S98-S104
48. Gabay C, Kushner I (1999) Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340:448-454