Induction of tumor stem cell differentiation - Novel strategy to overcome therapy resistance in gastric cancer

Langenbeck's Archives of Surgery

Volumn 398, Issue 4, 2013, Pages 603-608

  Zieker, Derek ^a   Bühler, Sarah ^a   Üstündag, Zeynep ^a   Königsrainer, Ingmar ^a   Manncke, Sebastian ^a   Bajaeifer, Khaled ^a   Vollmer, Jörg ^a   Fend, Falko ^a   Northoff, Hinnak ^a   Königsrainer, Alfred ^a   Glatzle, Jörg ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Cancer treatment; Gastric cancer; PGK1; Tumor stem cell

Indexed keywords

HERMES ANTIGEN; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE KINASE 1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CANCER CELL; CANCER CELL CULTURE; CANCER RESISTANCE; CANCER STEM CELL; CANCER TISSUE; CELL DIFFERENTIATION; CELL STRAIN MKN45; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PHENOTYPE; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA; TUMOR GROWTH;

ANIMALS; ANTIGENS, CD44; CELL DIFFERENTIATION; CELL LINE, TUMOR; HUMANS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PHOSPHOGLYCERATE KINASE; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84885317011     PISSN: 14352443     EISSN: 14352451     Source Type: Journal    
DOI: 10.1007/s00423-013-1058-5     Document Type: Conference Paper

References (19)

1. Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100(1):57-70 (Pubitemid 30046295)
2. Rosen JM, Jordan CT (2009) The increasing complexity of the cancer stem cell paradigm. Science 324(5935):1670-1673
3. Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367(6464):645-648 (Pubitemid 24067706)
4. Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8(10):755-768
5. Sullivan JP, Minna JD, Shay JW (2010) Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy. Cancer Metastasis Rev 29(1):61-72
6. Tennant DA, Duran RV, Boulahbel H, Gottlieb E (2009) Metabolic transformation in cancer. Carcinogenesis 30(8):1269-1280
7. Warburg O, Wind F, Negelein E (1927) The metabolism of tumors in the body. J Gen Physiol 8(6):519-530
8. Bracha AL, Ramanathan A, Huang S, Ingber DE, Schreiber SL (2010) Carbon metabolism-mediated myogenic differentiation. Nat Chem Biol 6(3):202-204
9. Wang J, Zhou J, Wu GS (2007) ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res 67(24):11933-11941
10. Duan Z, Lamendola DE, Yusuf RZ, Penson RT, Preffer FI, Seiden MV (2002) Overexpression of human phosphoglycerate kinase 1 (PGK1) induces a multidrug resistance phenotype. Anticancer Res 22(4):1933-1941 (Pubitemid 34857007)
11. Hwang T, Liang Y, Chien K, Yu J (2006) Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma. Proteomics 6(7):2259-2272
12. Zhang D, Tai LK, Wong LL, Chiu L, Sethi SK, Koay ESC (2005) Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer. Mol Cell Proteomics 4(11):1686-1696 (Pubitemid 41749262)
13. Zieker D, Konigsrainer I, Traub F, Nieselt K, Knapp B, Schillinger C, Stirnkorb C, Fend F, Northoff H, Kupka S, Brucher BLDM, Konigsrainer A (2008) PGK1 a potential marker for peritoneal dissemination in gastric cancer. Cell Physiol Biochem 21(5-6):429-436 (Pubitemid 351620296)
14. Zieker D, Konigsrainer I, Tritschler I, Loffler M, Beckert S, Traub F, Nieselt K, Buhler S, Weller M, Gaedcke J, Taichman RS, Northoff H, Brucher BLDM, Konigsrainer A (2010) Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer. Int J Cancer 126(6):1513-1520
15. Zieker D, Konigsrainer I, Weinreich J, Beckert S, Glatzle J, Nieselt K, Buhler S, Loffler M, Gaedcke J, Northoff H, Mannheim JG, Wiehr S, Pichler BJ, von Weyhern C, Brucher BLDM, Konigsrainer A (2010) Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging. Cell Physiol Biochem 26(2):147-154
16. Takaishi S, Okumura T, Tu S, Wang SSW, Shibata W, Vigneshwaran R, Gordon SAK, Shimada Y, Wang TC (2009) Identification of gastric cancer stem cells using the cell surface marker CD44. Stem Cells 27(5):1006-1020
17. Warburg O (1956) On the origin of cancer cells. Science 123(3191):309-314
18. Heddleston JM, Li Z, McLendon RE, Hjelmeland AB, Rich JN (2009) The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 8(20):3274-3284
19. Petrie K, Zelent A, Waxman S (2009) Differentiation therapy of acute myeloid leukemia: past, present and future. Curr Opin Hematol 16(2):84-91