Overexpression of human phosphoglycerate kinase 1 (PKG1) induces a multidrug resistance phenotype

Anticancer Research

Volumn 22, Issue 4, 2002, Pages 1933-1941

  Duan, Z ^a   Lamendola, D E ^a   Yusuf, R Z ^a   Penson, R T ^a   Preffer, F I ^a   Seiden, M V ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

ATP; Multidrug resistance; P glycoprotein; Paclitaxel; PGK 1

Indexed keywords

CISPLATIN; COMPLEMENTARY DNA; DOXORUBICIN; METHOTREXATE; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE KINASE 1; RHODAMINE; UNCLASSIFIED DRUG; VERAPAMIL; VINCRISTINE; VIRUS VECTOR;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CROSS RESISTANCE; DNA LIBRARY; DNA SEQUENCE; EXPRESSION VECTOR; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; NORTHERN BLOTTING; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BONE NEOPLASMS; CELL SURVIVAL; DRUG RESISTANCE, MULTIPLE; GENE LIBRARY; HUMANS; ISOENZYMES; OSTEOSARCOMA; PACLITAXEL; PHOSPHOGLYCERATE KINASE; VERAPAMIL;

EID: 0036336175     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Mechanisms of action of and resistance to antitubulin agents: Microtubule dynamics, drug transport, and cell death
2. p53-independent apoptosis induced by paclitaxel through an indirect mechanism
3. Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells
4. Anderson Cancer Center experience with Taxol in metastatic breast cancer
5. Taxol: A unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms
6. Taxoids: Effective agents in anthracycline-resistant breast cancer
7. Paclitaxel-resistant human ovarian cancer cells have mutant beta- tubulins that exhibit impaired paclitaxel-driven polymerization
8. Biochemistry of multidrug resistance mediated by the multidrug transporter
9. Altered expression of M beta 2, the class II beta-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance
10. The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein
11. The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation
12. The prognostic significance of Bcl-2 and p53 expression in ovarian carcinoma
13. BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway
14. BAX expression is associated with enhanced intracellular accumulation of paclitaxel: A novel role for BAX during chemotherapy-induced cell death
15. BAX protein expression and clinical outcome in epithelial ovarian cancer
16. High levels of p26BCL-2 oncoprotein retard taxol-induced apoptosis in human pre-B leukemia cells
17. Protein kinase C isoform expression and activity alter paclitaxel resistance in vitro
18. Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol)
19. Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression
20. Overexpression of c-erbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms
21. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemo sensitivity testing
22. Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen
23. Acquisition of taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells
24. International Committee for Standardization in Haematology: Recommended methods for red-cell enzyme analysis
25. A new case of phosphoglycerate kinase deficiency: PGK Creteil associated with rhabdomyolysis and lacking hemolytic anemia
26. Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
27. Drug resistance markers in epithelial ovarian carcinoma
28. A multidrug resistance transporter from human MCF-7 breast cancer cells
29. cDNA technologies and their application to drug resistance research: Power, potential and problems
30. Discovery of differentially expressed genes associated with paclitaxel resistance using cDNA array technology: Analysis of interleukin (IL) 6, IL-8, and monocyte chemotactic protein 1 in the paclitaxel-resistant phenotype
31. Identification of semaphorin E as a non-MDR drug resistance gene of human cancers
32. Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene
33. Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase
34. Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents
35. Increased sensitivity of an adriamycin-resistant human small cell lung carcinoma cell line to mitochondrial inhibitors
36. Identification of tumor markers in models of human colorectal cancer using a 19,200-element complementary DNA microarray
37. Expression of hypoxia-inducible genes in tumor cells