Synthesis and analgesic effects of novel β2-tryptophan hexapeptide analogs

Amino Acids

Volumn 45, Issue 4, 2013, Pages 983-988

  Bocheva, Adriana ^a   Nocheva, Hristina ^a   Pavlov, Nikola ^b   Todorov, Petar ^b   Calmès, Monique ^c   Martinez, Jean ^c   Naydenova, Emilia ^b  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY   (Bulgaria)

^c UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

HP latency; Nociceptin analogue; Nociception; NOP receptor; PP test; SPPS; Tryptophan analogues

Indexed keywords

ANALGESIC AGENT; BETA 2 TRYPTOPHAN HEXAPEPTIDE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; G(I) PROTEIN COUPLED N OFQ RECEPTOR; HEXAPEPTIDE; N (4 AMINO 2 METHYL 6 QUINOLINYL) 2 (4 ETHYLPHENOXYMETHYL)BENZAMIDE; NALOXONE; OPIATE RECEPTOR; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; EXPERIMENTAL TEST; HOT PLATE TEST; MALE; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PAW PRESSURE TEST; PRIORITY JOURNAL; RAT;

RATTUS NORVEGICUS;

ANALGESICS; ANIMALS; MALE; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PAIN MEASUREMENT; PAIN THRESHOLD; PRESSURE; RATS; RATS, WISTAR; TRYPTOPHAN;

EID: 84885300466     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-013-1555-4     Document Type: Article

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