Caffeine as an adjuvant therapy to opioids in cancer pain: A randomized, double-blind, placebo-controlled trial

Journal of Pain and Symptom Management

Volumn 46, Issue 4, 2013, Pages 474-482

  Suh, Sang Yeon ^a,b   Choi, Youn Seon ^c   Oh, Sang Cheul ^c   Kim, Young Sung ^d   Cho, Kyunghee ^d   Bae, Woo Kyung ^e   Lee, Ju Hyun ^f   Seo, Ah Ram ^a   Ahn, Hong Yup ^a  

^a Dongguk University   (South Korea)

^b Dongguk University Ilsan Hospital   (South Korea)

^c Korea University College of Medicine   (South Korea)

^d National Health Insurance Corporation   (South Korea)

^e Seoul National University Bundang Hospital   (South Korea)

^f Hanmaum Hospital   (South Korea)

Author keywords

Caffeine; cancer pain; opioid therapy; randomized controlled trial

Indexed keywords

ANTIDEPRESSANT AGENT; CAFFEINE; OPIATE; PLACEBO; SODIUM CHLORIDE;

ADJUVANT THERAPY; ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER PAIN; CANCER PATIENT; CLINICAL ARTICLE; CONFUSION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG EFFICACY; EMOTION; FATIGUE; FEMALE; HUMAN; INSOMNIA; MALE; NAUSEA; OUTCOME ASSESSMENT; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SADNESS; SLEEP DISORDER; UNSPECIFIED SIDE EFFECT;

CAFFEINE; CANCER PAIN; OPIOID THERAPY; RANDOMIZED CONTROLLED TRIAL;

AGED; ANALGESICS, OPIOID; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; CHEMOTHERAPY, ADJUVANT; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; PAIN; PAIN MEASUREMENT; PALLIATIVE CARE; PLACEBO EFFECT; TREATMENT OUTCOME;

EID: 84885291188     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2012.10.232     Document Type: Article

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