메뉴 건너뛰기




Volumn 115, Issue 7, 2013, Pages 951-953

Oral BH4: A novel remedy for age-related skin microvascular impairment during heat stress or fool's elixir?

Author keywords

[No Author keywords available]

Indexed keywords

5,6,7,8-TETRAHYDROBIOPTERIN; BIOPTERIN; DRUG DERIVATIVE; TETRAHYDROBIOPTERIN;

EID: 84885225847     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00785.2013     Document Type: Review
Times cited : (3)

References (12)
  • 2
    • 33748645122 scopus 로고    scopus 로고
    • 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: Effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling
    • Antoniades C, Shirodaria C, Warrick N, Cai S, de Bono J, Lee J, Leeson P, Neubauer S, Ratnatunga C, Pillai R, Refsum H, Channon KM. 5- Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation 114: 1193-1201, 2006.
    • (2006) Circulation , vol.114 , pp. 1193-1201
    • Antoniades, C.1    Shirodaria, C.2    Warrick, N.3    Cai, S.4    De Bono, J.5    Lee, J.6    Leeson, P.7    Neubauer, S.8    Ratnatunga, C.9    Pillai, R.10    Refsum, H.11    Channon, K.M.12
  • 3
    • 70350496588 scopus 로고    scopus 로고
    • Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: Relative importance of the de novo biopterin synthesis versus salvage pathways
    • Crabtree MJ, Tatham AL, Hale AB, Alp NJ, Channon KM. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways. J Biol Chem 284: 28128-28136, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 28128-28136
    • Crabtree, M.J.1    Tatham, A.L.2    Hale, A.B.3    Alp, N.J.4    Channon, K.M.5
  • 5
    • 0345532411 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells
    • Hattori Y, Nakanishi N, Akimoto K, Yoshida M, Kasai K. HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells. Arterioscler Thromb Vasc Biol 23: 176-182, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 176-182
    • Hattori, Y.1    Nakanishi, N.2    Akimoto, K.3    Yoshida, M.4    Kasai, K.5
  • 6
    • 33845502720 scopus 로고    scopus 로고
    • Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin
    • Holowatz LA, Thompson CS, Kenney WL. Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin. Am J Physiol Heart Circ Physiol 291: H2965-H2970, 2006.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Holowatz, L.A.1    Thompson, C.S.2    Kenney, W.L.3
  • 7
    • 58149138838 scopus 로고    scopus 로고
    • Vascular protection by tetrahydrobiopterin: Progress and therapeutic prospects
    • Katusic ZS, d'Uscio LV, Nath KA. Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects. Trends Pharmacol Sci 30: 48-54, 2009.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 48-54
    • Katusic, Z.S.1    D'Uscio, L.V.2    Nath, K.A.3
  • 8
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • Milstien S, Katusic Z. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 263: 681-684, 1999.
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 9
    • 44449088555 scopus 로고    scopus 로고
    • Reduced vascular tetrahydrobiopterin (BH4) and endothelial function with ageing: Is it time for a chronic BH4 supplementation trial in middle-aged and older adults?
    • Pierce GL, Larocca TJ. Reduced vascular tetrahydrobiopterin (BH4) and endothelial function with ageing: is it time for a chronic BH4 supplementation trial in middle-aged and older adults? J Physiol 586: 2673-2674, 2008.
    • (2008) J Physiol , vol.586 , pp. 2673-2674
    • Pierce, G.L.1    Larocca, T.J.2
  • 10
    • 84885226016 scopus 로고    scopus 로고
    • Oral sapropterin acutely augments reflex vasodilation in aged human skin through nitric oxide-dependent mechanisms
    • doi:10.1152/japplphysiol.00481.2013
    • Stanhewicz AE, Alexander LA, Kenney WL. Oral sapropterin acutely augments reflex vasodilation in aged human skin through nitric oxide-dependent mechanisms. J Appl Physiol; doi:10.1152/japplphysiol.00481.2013.
    • J Appl Physiol
    • Stanhewicz, A.E.1    Alexander, L.A.2    Kenney, W.L.3
  • 11
    • 84859611770 scopus 로고    scopus 로고
    • Local tetrahydrobiopterin administration augments reflex cutaneous vasodilation through nitric oxide-dependent mechanisms in aged human skin
    • Stanhewicz AE, Bruning RS, Smith CJ, Kenney WL, Holowatz LA. Local tetrahydrobiopterin administration augments reflex cutaneous vasodilation through nitric oxide-dependent mechanisms in aged human skin. J Appl Physiol 112: 791-797, 2012.
    • (2012) J Appl Physiol , vol.112 , pp. 791-797
    • Stanhewicz, A.E.1    Bruning, R.S.2    Smith, C.J.3    Kenney, W.L.4    Holowatz, L.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.