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Volumn 33, Issue 10, 2013, Pages 1107-1116

Cobicistat: A new boost for the treatment of human immunodeficiency virus infection

Author keywords

antiretrovirals; booster; cobicistat; GS 9350; HIV; human immunodeficiency virus; pharmacokinetic enhancer; ritonavir

Indexed keywords

ALFUZOSIN; AMIODARONE; ATAZANAVIR; COBICISTAT; COBICISTAT PLUS ELVITEGRAVIR PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; CONIVAPTAN; CREATININE; DARUNAVIR; DESIPRAMINE; DIGOXIN; EFAVIRENZ; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; ELVITEGRAVIR; ETRAVIRINE; FAMOTIDINE; MIDAZOLAM; OMEPRAZOLE; RIFAMPICIN; RITONAVIR; SIMVASTATIN;

EID: 84885222034     PISSN: 02770008     EISSN: 18759114     Source Type: Journal    
DOI: 10.1002/phar.1237     Document Type: Review
Times cited : (54)

References (37)
  • 1
    • 84855616052 scopus 로고    scopus 로고
    • Department of Health and Human Services March 2012. Accessed October 5
    • Department of Health and Human Services. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents, March 2012. Available from http://www.aidsinfo.nih.gov/contentfiles/lvguidelines/ adultandadolescentgl.pdf. Accessed October 5, 2012.
    • (2012) Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents
  • 2
    • 67649185287 scopus 로고    scopus 로고
    • Simplification of antiretroviral therapy to a single-tablet regimen consisting of efavirenz, emtricitabine, and tenofovir disoproxil fumarate versus unmodified antiretroviral therapy in virologically suppressed HIV-1-infected patients
    • DeJesus E, Young B, Morales-Ramirez JO, et al. Simplification of antiretroviral therapy to a single-tablet regimen consisting of efavirenz, emtricitabine, and tenofovir disoproxil fumarate versus unmodified antiretroviral therapy in virologically suppressed HIV-1-infected patients. J Acquir Immune Defic Syndr 2009; 51: 163-74.
    • (2009) J Acquir Immune Defic Syndr , vol.51 , pp. 163-174
    • Dejesus, E.1    Young, B.2    Morales-Ramirez, J.O.3
  • 3
    • 84857529579 scopus 로고    scopus 로고
    • Adherence to antiretroviral treatment and correlation with risk of hospitalization among commercially insured HIV patients in the United States
    • Sax PE, Meyers JL, Mugavero M, Davis KL,. Adherence to antiretroviral treatment and correlation with risk of hospitalization among commercially insured HIV patients in the United States. PLoS ONE 2012; 7: e31591.
    • (2012) PLoS ONE , vol.7
    • Sax, P.E.1    Meyers, J.L.2    Mugavero, M.3    Davis, K.L.4
  • 4
    • 77954618054 scopus 로고    scopus 로고
    • One-pill once-a-day HAART: A simplification strategy that improves adherence and quality of life of HIV-infected subjects
    • Airoldi M, Zaccaelli M, Bisi L, et al. One-pill once-a-day HAART: a simplification strategy that improves adherence and quality of life of HIV-infected subjects. Patient Prefer Adherence 2010; 4: 115-25.
    • (2010) Patient Prefer Adherence , vol.4 , pp. 115-125
    • Airoldi, M.1    Zaccaelli, M.2    Bisi, L.3
  • 5
    • 77149123315 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of GS-9350: A novel pharmacokinetic enhancer without anti-HIV activity
    • Mathias AA, German P, Murray BP, et al. Pharmacokinetics and pharmacodynamics of GS-9350: a novel pharmacokinetic enhancer without anti-HIV activity. Clin Pharmacol Ther 2010; 87: 322-9.
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 322-329
    • Mathias, A.A.1    German, P.2    Murray, B.P.3
  • 6
    • 36549014231 scopus 로고    scopus 로고
    • Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients
    • Youle M,. Overview of boosted protease inhibitors in treatment- experienced HIV-infected patients. J Antimicrob Chemother 2007; 60: 1195-205.
    • (2007) J Antimicrob Chemother , vol.60 , pp. 1195-1205
    • Youle, M.1
  • 7
    • 13644249455 scopus 로고    scopus 로고
    • Protease-inhibitor boosting in the treatment-experienced patient
    • Gallant JE,. Protease-inhibitor boosting in the treatment-experienced patient. AIDS Rev 2004; 6: 226-33.
    • (2004) AIDS Rev , vol.6 , pp. 226-233
    • Gallant, J.E.1
  • 8
    • 28444452174 scopus 로고    scopus 로고
    • The effect of low-dose ritonavir monotherapy on fasting serum lipid concentrations
    • Shafran SD, Mashinter LD, Roberts SE,. The effect of low-dose ritonavir monotherapy on fasting serum lipid concentrations. HIV Med 2005; 6: 421-5.
    • (2005) HIV Med , vol.6 , pp. 421-425
    • Shafran, S.D.1    Mashinter, L.D.2    Roberts, S.E.3
  • 9
    • 48249104628 scopus 로고    scopus 로고
    • Induction effects of ritonavir: Implications for drug interactions
    • Foisy MM, Yakiwchuk EM, Hughes CA,. Induction effects of ritonavir: implications for drug interactions. Ann Pharmacother 2008; 42: 1048-59.
    • (2008) Ann Pharmacother , vol.42 , pp. 1048-1059
    • Foisy, M.M.1    Yakiwchuk, E.M.2    Hughes, C.A.3
  • 10
    • 1542410398 scopus 로고    scopus 로고
    • Ritonavir-PEG 8000 amorphous solid dispersions: In vitro and in vivo evaluations
    • Law D, Schmitt EA, Marsh KC, et al. Ritonavir-PEG 8000 amorphous solid dispersions: In vitro and in vivo evaluations. J Pharm Sci 2004; 93: 563-70.
    • (2004) J Pharm Sci , vol.93 , pp. 563-570
    • Law, D.1    Schmitt, E.A.2    Marsh, K.C.3
  • 11
    • 80052917901 scopus 로고    scopus 로고
    • Phase 2 study of cobicistat versus ritonavir each with once-daily atazanavir and fixed-dosed emtricitabine/tenofovir df in the initial treatment of HIV infection
    • Elion R, Cohen C, Gathe J, et al. Phase 2 study of cobicistat versus ritonavir each with once-daily atazanavir and fixed-dosed emtricitabine/ tenofovir df in the initial treatment of HIV infection. AIDS 2011; 25: 1881-6.
    • (2011) AIDS , vol.25 , pp. 1881-1886
    • Elion, R.1    Cohen, C.2    Gathe, J.3
  • 12
    • 84865714929 scopus 로고    scopus 로고
    • Effect of cobicistat on glomerular filtration rate in subjects with normal and impaired renal function
    • German P, Liu HC, Szwarcberg J, et al. Effect of cobicistat on glomerular filtration rate in subjects with normal and impaired renal function. J Acquir Immune Defic Syndr 2012; 61: 32-40.
    • (2012) J Acquir Immune Defic Syndr , vol.61 , pp. 32-40
    • German, P.1    Liu, H.C.2    Szwarcberg, J.3
  • 15
    • 77956150896 scopus 로고    scopus 로고
    • Cobicistat (GS-9350): A potent and selective inhibitor of human CYP3A as a novel pharmacoenhancer
    • Xu L, Liu H, Murray B, et al. Cobicistat (GS-9350): a potent and selective inhibitor of human CYP3A as a novel pharmacoenhancer. ACS Med Chem Lett. 2010; 1: 209-13.
    • (2010) ACS Med Chem Lett. , vol.1 , pp. 209-213
    • Xu, L.1    Liu, H.2    Murray, B.3
  • 16
    • 84255173321 scopus 로고    scopus 로고
    • Antiretroviral drug interactions: Overview of interactions involving new and investigational agents and the role of therapeutic drug monitoring for management
    • Rathbun C, Liedtke M,. Antiretroviral drug interactions: overview of interactions involving new and investigational agents and the role of therapeutic drug monitoring for management. Pharmaceutics. 2011; 3: 745-81.
    • (2011) Pharmaceutics. , vol.3 , pp. 745-781
    • Rathbun, C.1    Liedtke, M.2
  • 17
    • 84900870346 scopus 로고    scopus 로고
    • Lexi-Comp OnlineTM, Lexi-Drugs Online™, Hudson, Ohio: Lexi-Comp, Inc. May 1
    • Lexi-Comp OnlineTM, Lexi-Drugs Online™, Hudson, Ohio: Lexi-Comp, Inc.; May 1, 2012.
    • (2012)
  • 18
    • 84900858407 scopus 로고    scopus 로고
    • HIV InSite, University of California San Francisco Accessed May 1
    • ®), 2011. Available from http://hivinsite.ucsf.edu/insite?page= ar-00-02¶m=8&post=4. Accessed May 1, 2012.
    • (2011) ®)
  • 19
    • 84872660765 scopus 로고    scopus 로고
    • Effect of acid reducing agents on the relative bioavailability and pharmacokinetics of cobicistat-boosted elvitegravir (abstract P-13)
    • Miami, FL, April 13-15
    • Mathias A, Koziara J, Wei L, Warren D, Kearney BP,. Effect of acid reducing agents on the relative bioavailability and pharmacokinetics of cobicistat-boosted elvitegravir (abstract P-13). Presented at the 12th International Workshop on Clinical Pharmacology of HIV Therapy, Miami, FL, April 13-15, 2011.
    • (2011) 12th International Workshop on Clinical Pharmacology of HIV Therapy
    • Mathias, A.1    Koziara, J.2    Wei, L.3    Warren, D.4    Kearney, B.P.5
  • 20
    • 78049293198 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of an integrase and novel pharmacoenhancer-containing single-tablet fixed-dosed combination regimen for the treatment of HIV
    • German P, Warren D, West S, Hui J, Kearney BP,. Pharmacokinetics and bioavailability of an integrase and novel pharmacoenhancer-containing single-tablet fixed-dosed combination regimen for the treatment of HIV. J Acquir Immune Defic Syndr 2010; 55: 323-9.
    • (2010) J Acquir Immune Defic Syndr , vol.55 , pp. 323-329
    • German, P.1    Warren, D.2    West, S.3    Hui, J.4    Kearney, B.P.5
  • 21
    • 73549097349 scopus 로고    scopus 로고
    • Pharmacokinetic boosting of atazanavir with the pharmacoenhancer GS-9350 versus ritonavir (abstract 614)
    • San Francisco, California, September 12-15
    • Ramanathan S, Warren D, Wei L, Kearney BP,. Pharmacokinetic boosting of atazanavir with the pharmacoenhancer GS-9350 versus ritonavir (abstract 614). Presented at the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California, September 12-15, 2009.
    • (2009) 49th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Ramanathan, S.1    Warren, D.2    Wei, L.3    Kearney, B.P.4
  • 22
    • 80052932492 scopus 로고    scopus 로고
    • Relative bioavailability and pharmacokinetics of darunavir when boosted with the pharmacoenhancer GS-9350 versus ritonavir (abstract 28)
    • Sorrento, Italy, April 7-9
    • Mathias A, Liu HC, Warren D, Sekar V, Kearney BP,. Relative bioavailability and pharmacokinetics of darunavir when boosted with the pharmacoenhancer GS-9350 versus ritonavir (abstract 28). Presented at the 11th International Workshop on Clinical Pharmacology of HIV Therapy, Sorrento, Italy, April 7-9, 2010.
    • (2010) 11th International Workshop on Clinical Pharmacology of HIV Therapy
    • Mathias, A.1    Liu, H.C.2    Warren, D.3    Sekar, V.4    Kearney, B.P.5
  • 24
    • 79953735724 scopus 로고    scopus 로고
    • Randomized, phase 2 evaluation of two single-tablet regimens elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for the initial treatment of HIV infection
    • Cohen C, Elion R, Ruane P, et al. Randomized, phase 2 evaluation of two single-tablet regimens elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for the initial treatment of HIV infection. AIDS 2011; 25: F7-12.
    • (2011) AIDS , vol.25
    • Cohen, C.1    Elion, R.2    Ruane, P.3
  • 26
    • 84862876886 scopus 로고    scopus 로고
    • Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: A randomised, double-blind, phase 3 trial, analysis of results after 48 weeks
    • Sax PE, DeJesus E, Mills A, et al. Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks. Lancet 2012; 379: 2439-48.
    • (2012) Lancet , vol.379 , pp. 2439-2448
    • Sax, P.E.1    Dejesus, E.2    Mills, A.3
  • 27
    • 84862843404 scopus 로고    scopus 로고
    • Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: A randomised, double-blind, phase 3, non-inferiority trial
    • DeJesus E, Rockstroh JK, Henry K, et al. Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet 2012; 379: 2429-38.
    • (2012) Lancet , vol.379 , pp. 2429-2438
    • Dejesus, E.1    Rockstroh, J.K.2    Henry, K.3
  • 28
    • 84900870720 scopus 로고    scopus 로고
    • Gilead Sciences, Inc. Stribild package insert. Foster City, CA.
    • Gilead Sciences, Inc. Stribild package insert. Foster City, CA; 2012.
    • (2012)
  • 33
    • 84900849455 scopus 로고    scopus 로고
    • Pharmacokinetics of EVG/COBI/FTC/TDF single tablet regimen following treatment with EFV/FTC/TDF (Atripla) in healthy subjects (abstract O-21)
    • Barcelona, Spain, April 16-18
    • Ramanathan S, Wang H, Custodio J, et al. Pharmacokinetics of EVG/COBI/FTC/TDF single tablet regimen following treatment with EFV/FTC/TDF (Atripla) in healthy subjects (abstract O-21). Presented at the 13th International Workshop on Clinical Pharmacology of HIV Therapy, Barcelona, Spain, April 16-18, 2012.
    • (2012) 13th International Workshop on Clinical Pharmacology of HIV Therapy
    • Ramanathan, S.1    Wang, H.2    Custodio, J.3
  • 37


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.