Empirical antimicrobial therapy for critically ill patients with Acinetobacter baumannii bacteremia: Combination is better

Journal of Microbiology, Immunology and Infection

Volumn 46, Issue 5, 2013, Pages 397-398

  Lee, Nan Yao ^a   Lee, Jen Chieh ^a   Li, Ming Chi ^a   Li, Chia Wen ^a   Ko, Wen Chien ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CARBAPENEM; SULBACTAM;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL THERAPY; BACTERIUM ISOLATE; COMBINATION CHEMOTHERAPY; CRITICALLY ILL PATIENT; DISEASE SEVERITY; HEALTH CARE FACILITY; HUMAN; LETTER; MONOTHERAPY; MORTALITY; NONHUMAN; RISK FACTOR;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; BACTEREMIA; BETA-LACTAM RESISTANCE; CARBAPENEMS; FEMALE; HUMANS; MALE;

EID: 84885180256     PISSN: 16841182     EISSN: 19959133     Source Type: Journal    
DOI: 10.1016/j.jmii.2013.03.004     Document Type: Letter

References (5)

1. Lee N.Y., Lee H.C., Ko N.Y., Chang C.M., Shih H.I., Wu C.J., et al. Clinical and economic impact of multidrug resistance in nosocomial Acinetobacter baumannii bacteremia. Infect Control Hosp Epidemiol 2007, 28:713-719.
2. Huang S.T., Chiang M.C., Kuo S.C., Lee Y.T., Chiang T.H., Yang S.P., et al. Risk factors and clinical outcomes of patients with carbapenem-resistant Acinetobacter baumannii bacteremia. JMicrobiol Immunol Infect 2012, 45:356-362.
3. Micek S.T., Welch E.C., Khan J., Pervez M., Doherty J.A., Reichley R.M., et al. Empiric combination antibiotic therapy is associated with improved outcome against sepsis due to gram-negative bacteria: a retrospective analysis. Antimicrob Agents Chemother 2010, 54:1742-1748.
4. Tamma P.D., Cosgrove S.E., Maragakis L.L. Combination therapy for treatment of infections with gram-negative bacteria. Clin Microbiol Rev 2012, 25:450-470.
5. Lee N.Y., Wang C.L., Chuang Y.C., Yu W.L., Lee H.C., Chang C.M., et al. Combination carbapenem-sulbactam therapy for critically ill patients with multidrug-resistant Acinetobacter baumannii bacteremia: four case reports and an invitro combination synergy study. Pharmacotherapy 2007, 27:1506-1511.