Protective effects of protein transduction domain-metallothionein fusion proteins against hypoxia- and oxidative stress-induced apoptosis in an ischemia/reperfusion rat model

Journal of Controlled Release

Volumn 169, Issue 3, 2013, Pages 306-312

  Lim, Kwang Suk ^a   Cha, Min Ji ^b   Kim, Jang Kyoung ^a   Park, Eun Jeong ^a   Chae, Ji Won ^a   Rhim, Taiyoun ^a   Hwang, Ki Chul ^b   Kim, Yong Hee ^a  

^a Hanyang University   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Anti oxidant; Ischemia reperfusion; Metallothionein; Myocardial infarction; Protein transduction domain

Indexed keywords

BACTERIOPHAGES; CARDIOLOGY; CELL DEATH; DISEASES; EFFICIENCY; HEART; OXYGEN SUPPLY; RATS; RECOMBINANT PROTEINS;

ISCHEMIA/REPERFUSION; ISCHEMIC HEART DISEASE; METALLOTHIONEINS; MYOCARDIAL INFARCTION; PHARMACEUTICAL AGENTS; PROTEIN TRANSDUCTION DOMAINS; THERAPEUTIC POTENTIALS; TRANSDUCTION EFFICIENCY;

PROTEINS;

CASPASE 3; HYBRID PROTEIN; METALLOTHIONEIN; REACTIVE OXYGEN METABOLITE; TRANSACTIVATOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HEART FUNCTION; HEART INFARCTION; HYPERGLYCEMIA; HYPOXIA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

EID: 84885176915     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.01.023     Document Type: Article

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