Differentiation state affects morphine induced cell regulation in neuroblastoma cultured cells

Neuroscience Letters

Volumn 555, Issue , 2013, Pages 51-56

  Fiore, Giovina ^a   Ghelardini, Carla ^b   Bruni, Giancarlo ^a   Guarna, Massimo ^a   Bianchi, Enrica ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cell differentiation; Cell survival; Morphine; Neuroblastoma cells; Signaling pathway

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL COUNT; CELL DEATH; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; NEUROBLASTOMA CELL; PRIORITY JOURNAL; STIMULATION;

Μ OPIOID RECEPTOR; ΜOR; ANTI-GROWTH-ASSOCIATED PROTEIN 43; C-JUN N-TERMINAL KINASE; CELL DIFFERENTIATION; CELL SURVIVAL; ERK; EXTRACELLULAR SIGNAL-REGULATED KINASE; GAP43; GFAP; GLIAL FIBRILLARY ACIDIC PROTEIN; JNK; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; MORPHINE; MORPHINE HCL; NEUROBLASTOMA CELLS; NEUROFILAMENT M; NEURON-SPECIFIC ENOLASE; NF-M; NSE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PPAR; RA; RETINOIC ACID; SIGNALING PATHWAY;

ANALGESICS, OPIOID; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHINE; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS;

EID: 84885138733     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.07.039     Document Type: Article

References (23)

1. Sueoka E., Sueoka N., Kai Y., Okabe S., Suganuma M., Kanematsu K., Yamamoto T., Fujiki H. Anticancer activity of morphine and its synthetic derivative, KT-90, mediated through apoptosis and inhibition of NF-kappaB activation. Biochemical and Biophysical Research Communications 1998, 252:566-570.
2. Zagon I.S., McLaughlin P.J. Opioid antagonist (naltrexone) stimulation of cell proliferation in human and animal neuroblastoma and human fibrosarcoma cells in culture. Neuroscience 1990, 37:223-226.
3. Koo K.L., Tejwani G.A., Abou-Issa H. Relative efficacy of the opioid antagonist naltrexone, on the initiation and promotion phases of rat mammary carcinogenesis. Anticancer Research 1983, 16:1893-1898.
4. Hatzoglou A., Ouafik L., Bakogeorgou E., Thermos K., Castanas E. Morphine cross-reacts with somatostatin receptor SSTR2 in the T47D human breast cancer cell line and decreases cell growth. Cancer Research 1995, 55:5632-5636.
5. Lewis J.W., Shavit Y., Terman G.W., Gale R.P., Liebeskind J.C. Stress and morphine affect survival of rats challenged with a mammary ascites tumor (MAT 13762B). Natural Immunity and Cell Growth Regulation 1983-1984, 3:43-50.
6. Gupta K., Kshirsagar S., Chang L., Schwartz R., Law P.Y., Yee D., Hebbel R.P. Morphine stimulates angiogenesis by activating proangiogenic and survival-promoting signaling and promotes breast tumor growth. Cancer Research 2002, 62:4491-4498.
7. Yu V.C., Sadée W. Efficacy and tolerance of narcotic analgesics at the mu opioid receptor in differentiated human neuroblastoma cells. Journal of Pharmacology and Experimental Therapeutics 1988, 245:350-355.
8. Biedler J.L., Helson L., Spengler B.A. Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Research 1973, 33:2643-2652.
9. Ghelardini C., Galeotti N., Vivoli E., Norcini M., Zhu W., Stefano G.B., Guarna M., Bianchi E. Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception. Journal of Neurochemistry 2008, 105:91-100.
10. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951, 193:265-275.
11. Goswami R., Dawson S.A., Dawson G. Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11kappa7) neurons. Journal of Neurochemistry 1998, 70:1376-1382.
12. Yin D.L., Ren X.H., Zheng Z.L., Pu L., Jiang L.Z., Ma L., Pei G. Etorphine inhibits cell growth and induces apoptosis in SK-N-SH cells: involvement of pertussis toxin-sensitive G proteins. Neuroscience Research 1997, 29:121-127.
13. Harper S.J., LoGrasso P. Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38. Cell Signaling 2001, 13:299-310.
14. Singhal P., Kapasi A., Reddy K., Franki N. Opiates promote T cell apoptosis through JNK and caspase pathway. Advances in Experimental Medicine and Biology 2001, 493:127-135.
15. Lin X., Wang Y.J., Li Q., Hou Y.Y., Hong M.H., Cao Y.L., Chi Z.Q., Liu J.G. Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway. FEBS Journal 2009, 276:2022-2036.
16. Hengartner M.O. The biochemistry of apoptosis. Nature 2000, 407(6805):770-776.
17. O'Connor L., Strasser A., O'Reilly L.A., Hausmann G., Adams J.M., Cory S., Huang D.C. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO Journal 1998, 17:384-395.
18. Molenaar J.J., Ebus M.E., Koster J., van Sluis P., van Noesel C.J., Versteeg R., Caron H.N. Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma. Cancer Research 2008, 68:2599-2609.
19. Matthes H.W., Maldonado R., Simonin F., Valverde O., Slowe S., Kitchen I., Befort K., Dierich A., Le Meur M., Dollé P., Tzavara E., Hanoune J., Roques B.P., Kieffer B.L. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 1996, 383:819-823.
20. Pfeiffer M., Koch T., Schröder H., Laugsch M., Höllt V., Schulz S. Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. Journal of Biological Chemistry 2002, 277:19762-19772.
21. Mou L., Lankford-Turner P., Leander M.V., Bissonnette R.P., Donahoe R.M., Royal W. RXR-induced TNF-alpha suppression is reversed by morphine in activated U937 cells. Journal of Neuroimmunology 2004, 147:99-105.
22. Royal W., Leander M., Chen Y.E., Major E.O., Bissonnette R.P. Nuclear receptor activation and interaction with morphine. Journal of Neuroimmunology 2004, 157:61-65.
23. Yoshimura R., Matsuyama M., Segawa Y., Hase T., Mitsuhashi M., Tsuchida K., Wada S., Kawahito Y., Sano H., Nakatani T. Expression of peroxisome proliferator-activated receptors (PPARs) in human urinary bladder carcinoma and growth inhibition by its agonists. International Journal of Cancer 2003, 104:597-602.