High-content screening assay for identification of chemicals impacting cardiovascular function in zebrafish embryos

Environmental Science and Technology

Volumn 47, Issue 19, 2013, Pages 11302-11310

  Yozzo, Krystle L ^a   Isales, Gregory M ^a   Raftery, Tara D ^a   Volz, David C ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC LOOPING; CARDIOVASCULAR FUNCTION; HIGH-CONTENT SCREENING; INDEPENDENT CONTROL; POST-FERTILIZATION; TRANSGENIC ZEBRAFISH; VASCULAR ENDOTHELIAL CELLS; ZEBRAFISH EMBRYOS;

ASSAYS; ENDOTHELIAL CELLS; OPTIMIZATION; PLANTS (BOTANY);

CHEMICALS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CHEMICAL COMPOUND; CIPERMETHRIN; CL 14AS 1; ENDOSULFAN; ENHANCED GREEN FLUORESCENT PROTEIN; ESTRADIOL; GENISTEIN; IMIDACLOPRID; NICOTINE; PARAOXON; PYRIDABEN; TRICAINE; UNCLASSIFIED DRUG;

BIOASSAY; BIOMARKER; CARDIOVASCULAR SYSTEM; CHEMICAL POLLUTANT; CONCENTRATION (COMPOSITION); CYPRINID; EMBRYO; HATCHING; IMAGE ANALYSIS; OPTIMIZATION; POLLUTION EXPOSURE; SUBLETHAL EFFECT; SURVIVAL; TOXICOLOGY;

ANIMAL EXPERIMENT; ARTERIAL CIRCULATION; ARTICLE; BODY HEIGHT; CARDIOTOXICITY; CARDIOVASCULAR FUNCTION; EMBRYO; ENDOTHELIUM CELL; FEMALE; HEART RATE; IMAGE ANALYSIS; MALE; NONHUMAN; ORGANOGENESIS; PERICARDIUM; SCREENING; SURVIVAL RATE; VASCULAR ENDOTHELIUM; VENOUS CIRCULATION; ZEBRA FISH;

AMINOBENZOATES; ANESTHETICS; ANIMALS; BODY SIZE; CARDIOTOXINS; CARDIOVASCULAR SYSTEM; CORONARY CIRCULATION; EMBRYO, NONMAMMALIAN; HEART RATE; HIGH-THROUGHPUT SCREENING ASSAYS; ZEBRAFISH;

EID: 84885124864     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es403360y     Document Type: Article

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