1,25-Dihydroxyvitamin D decreases HTRA1 promoter activity in the rhesus monkey - A plausible explanation for the influence of vitamin D on age-related macular degeneration?

Experimental Eye Research

Volumn 116, Issue , 2013, Pages 234-239

  Pahl, Lisa ^a   Schubert, Stephanie ^a   Skawran, Britta ^a   Sandbothe, Maria ^a   Schmidtke, Jörg ^a   Stuhrmann, Manfred ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

A ; AD; Age related macular degeneration; AMD; ARMS2; CNV; FBS; GA; HTRA1; LD; Rhesus monkey; RPE; SNP; VDR; Vitamin D

Indexed keywords

CALCITRIOL; HTRA SERINE PEPTIDASE 1; LUCIFERASE; MESSENGER RNA; METHYLDOPA; SERINE PROTEINASE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; COMPUTER MODEL; CONTROLLED STUDY; DRUSEN; ENZYME ACTIVITY; EYE; GENE EXPRESSION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; RHESUS MONKEY; SINGLE NUCLEOTIDE POLYMORPHISM;

AΒ; AD; AGE-RELATED MACULAR DEGENERATION; ALZHEIMER'S DISEASE; AMD; AMD-RELATED MACULOPATHY SUSCEPTIBILITY 2; AMYLOID Β; ARMS2; CHOROIDAL NEOVASCULARISATION; CNV; FBS; FETAL BOVINE SERUM; GA; GEOGRAPHIC ATROPHY; HIGH-TEMPERATURE REQUIREMENT FACTOR A1; HTRA1; LD; LINKAGE DISEQUILIBRIUM; RETINAL PIGMENT EPITHELIUM; RHESUS MONKEY; RPE; SINGLE NUCLEOTIDE POLYMORPHISM; SNP; VDR; VITAMIN D; VITAMIN D RECEPTOR;

ALLELES; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA; GENE EXPRESSION REGULATION; GENOTYPE; MACACA MULATTA; MACULAR DEGENERATION; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA; SERINE ENDOPEPTIDASES; VITAMIN D; VITAMINS;

EID: 84885086603     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2013.09.012     Document Type: Article

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