Cyclodextrin formulation of the marine natural product pseudopterosin a uncovers optimal pharmacodynamics in proliferation studies of human umbilical vein endothelial cells

Marine Drugs

Volumn 11, Issue 9, 2013, Pages 3258-3271

  Day, Daniel R ^a   Jabaiah, Suraya ^a   Jacobs, Robert S ^a   Little, R Daniel ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Human umbilical vein endothelial cells (HUVEC); Hydroxypropyl beta cyclodextrin (HP CD); Log P; Proliferation; Pseudopterosins

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; CREMOPHOR; DIMETHYL SULFOXIDE; GROWTH FACTOR; NATURAL PRODUCT; PSEUDOPTEROSIN A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL KINETICS; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; EAR EDEMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOPHILICITY; MALE; MIGRATION INHIBITION; MOLECULAR MODEL; MOUSE; NONHUMAN; PHARMACODYNAMICS; PROTEIN DEPLETION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION; UMBILICAL VEIN ENDOTHELIAL CELL; WOUND HEALING;

CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; DITERPENES; GLYCOSIDES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS;

EID: 84885082014     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md11093258     Document Type: Article

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