TNF induces phenotypic modulation in cerebral vascular smooth muscle cells: Implications for cerebral aneurysm pathology

Journal of Cerebral Blood Flow and Metabolism

Volumn 33, Issue 10, 2013, Pages 1564-1573

  Ali, Muhammad S ^a   Starke, Robert M ^a,b   Jabbour, Pascal M ^a   Tjoumakaris, Stavropoula I ^a   Gonzalez, L Fernando ^a   Rosenwasser, Robert H ^a   Owens, Gary K ^b   Koch, Walter J ^c   Greig, Nigel H ^d   Dumont, Aaron S ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Cerebral aneurysm; Cerebral vascular smooth muscle cells; Smooth muscle cell phenotypic modulation; TNF alpha

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ALPHA SMOOTH MUSCLE ACTIN 22; GELATINASE B; INTERLEUKIN 1BETA; KRUPPEL LIKE FACTOR 4; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOCARDIN; MYOSIN; SMALL INTERFERING RNA; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; 3,6'-DITHIOTHALIDOMIDE; GENETIC MARKER; KRUPPEL LIKE FACTOR; NUCLEAR PROTEIN; THALIDOMIDE; TRANSACTIVATOR PROTEIN; TRANSCRIPTOME; 3,6' DITHIOTHALIDOMIDE; DRUG DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ARTERY ANEURYSM; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG INHIBITION; EPIGENETIC REPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; HEMODYNAMIC STRESS; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BRAIN CIRCULUS ARTERIOSUS; CAROTID ARTERY; CELL CULTURE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENETIC EPIGENESIS; GENETIC MARKER; GENETICS; IMMUNOLOGY; INTRACRANIAL ANEURYSM; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; DRUG ANTAGONISM; DRUG EFFECT;

ANIMALS; APOPTOSIS; CAROTID ARTERIES; CELL DIFFERENTIATION; CELLS, CULTURED; CIRCLE OF WILLIS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIGENESIS, GENETIC; GENETIC MARKERS; INTRACRANIAL ANEURYSM; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MUSCLE, SMOOTH, VASCULAR; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; RATS; THALIDOMIDE; TRANS-ACTIVATORS; TRANSCRIPTOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885022290     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.109     Document Type: Article

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