4-[18F]Fluoro-m-hydroxyphenethylguanidine: A radiopharmaceutical for quantifying regional cardiac sympathetic nerve density with positron emission tomography

Journal of Medicinal Chemistry

Volumn 56, Issue 18, 2013, Pages 7312-7323

  Jang, Keun Sam ^a   Jung, Yong Woon ^a   Gu, Guie ^a   Koeppe, Robert A ^a   Sherman, Phillip S ^a   Quesada, Carole A ^a   Raffel, David M ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 FLUORO M HYDROXYPHENETHYLGUANIDINE F 18; DESIPRAMINE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; 4 FLUORO 3 HYDROXYPHENETHYLGUANIDINE; 4-FLUORO-3-HYDROXYPHENETHYLGUANIDINE; DIAGNOSTIC AGENT; FLUORINE; GUANIDINE DERIVATIVE; PHENETHYLAMINE DERIVATIVE;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIAC IMAGING; CHEMICAL STRUCTURE; DENSITY; DOSIMETRY; DRUG CLEARANCE; DRUG SYNTHESIS; DRUG UPTAKE; FLUORINATION; HEART NERVE; LIVER; LUNG; NEUROBLASTOMA; NONHUMAN; NUCLEOPHILICITY; PHARMACOLOGICAL BLOCKING; PHEOCHROMOCYTOMA; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOCHEMISTRY; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RHESUS MONKEY; SYMPATHETIC NERVE; ADRENERGIC SYSTEM; ANIMAL; CHEMISTRY; FEMALE; HAPLORHINI; HEART; HUMAN; INNERVATION; MALE; METABOLISM; METHODOLOGY; RADIATION DOSE; SCINTISCANNING; TRANSPORT AT THE CELLULAR LEVEL; DIAGNOSTIC USE; PROCEDURES;

ADRENAL GLANDS; ANIMALS; BIOLOGICAL TRANSPORT; FEMALE; FLUORINE RADIOISOTOPES; GUANIDINES; HAPLORHINI; HEART; HUMANS; MALE; PHENETHYLAMINES; POSITRON-EMISSION TOMOGRAPHY; RADIATION DOSAGE; RADIOCHEMISTRY; RADIOPHARMACEUTICALS; RATS; SYMPATHETIC NERVOUS SYSTEM;

EID: 84885000928     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400770g     Document Type: Article

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