Efficacy of ketoprofen vs. ibuprofen and diclofenac: A systematic review of the literature and meta-analysis

Clinical and Experimental Rheumatology

Volumn 31, Issue 5, 2013, Pages 731-738

  Sarzi Puttini, Piercarlo ^a   Atzeni, Fabiola ^a   Lanata, Luigi ^b   Bagnasco, Michela ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b Chemistry Section   (Italy)

Author keywords

Diclofenac; Efficacy; Ibuprofen; ketoprofen

Indexed keywords

DICLOFENAC; FENOPROFEN; IBUPROFEN; INDOMETACIN; KETOPROFEN; PLACEBO;

ANKYLOSING SPONDYLITIS; ARTICLE; DISEASE SEVERITY; DRUG EFFICACY; DYSMENORRHEA; HUMAN; LOW BACK PAIN; META ANALYSIS; MYALGIA; OSTEOARTHRITIS; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RHEUMATOID ARTHRITIS; SCORING SYSTEM; SHOULDER PAIN; SPORT INJURY; SYSTEMATIC REVIEW; VISUAL ANALOG SCALE;

ADMINISTRATION, ORAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DICLOFENAC; FEMALE; HUMANS; IBUPROFEN; KETOPROFEN; MALE; PAIN; PAIN MEASUREMENT; PATIENT SELECTION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

EID: 84884971983     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. SARZI-PUTTINI P, ATZENI F, LANATA L et al.: Pain and ketoprofen: what is its role in clinical practice? Reumatismo 2010; 62: 172-88.
2. MOORE N: Forty years of ibuprofen use. Int J Clin Pract 2003; 135 (Suppl.): 28-31.
3. GAN TJ: Diclofenac: an update on its mechanism of action and safety profile. Curr Med Res Opin 2010; 26: 1715-31.
4. WALKER JL: Interrelationships of SRS-A production and arachidonic acid metabolism in human lung tissue. Adv Prostaglandin Thromboxane Res 1980; 6: 115-9.
5. DíAZ-REVAL MI, VENTURA-MARTíNEZ R, DÉCIGA-CAMPOS M, TERRóN JA, CABRÉ F, LóPEZ-MUñOZ FJ: Evidence for a central mechanism of action of S-(+)-ketoprofen. Eur J Pharmacol 2004; 483: 241-8.
6. BJöRKMAN R: Central antinociceptive effects of nonsteroidal anti-inflammatory drugs and paracetamol: experimental studies in the rat. Acta Anaesthesiol Scand 1995; 103: 1-44.
7. OSSIPOV MH, JERUSSI TP, REN K, SUN H, PORRECA F: Differential effects of spinal (R)-ketoprofen and (S)-ketoprofen against signs of neuropathic pain and tonic nociception: evidence for a novel mechanism of action of (R)-ketoprofen against tactile allodynia. Pain 2000; 87: 193-9.
8. JOKHIO IA, SIDDIQUI KA, WARAICH T, ABBAS M, ALI A: Study of efficacy and tolerance of ketoprofen and diclofenac sodium in the treatment of acute rheumatic and traumatic conditions. J Pak Med Assoc 1998; 48: 373-6.
9. ROBBINS D, TAYLOR MAH, BROWN MD, McILWAIN H: Ketoprofen versus ibuprofen for acute sports injuries: are there differences between nonsteroidal anti-inflammatory drugs? Curr Ther Res 1990; 48: 780-9.
10. MOHER D, LIBERATI A, TEZTLAFF J, ALTMAN G, PRISMA Group: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Int Med 2009; 51: 1-7.
11. HIGGINS JPT, GREEN S: Cochrane Handbook for Systematic Reviews of Interventions. Available: www.cochrane-handbook.org. Accessed 2011 Mar 20.
12. JADAD AR, MOORE RA, CARROLL D et al.: Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17: 1-12.
13. ARMITAGE P, BERRY G, MATTHEWS JNS: Statistical methods in Medical Research. 4rd Edition, Blackwell Scientific Publications, Oxford, England. 2002.
14. SUTTON AJ, ABRAMS KR, JONES DR, SHELDON TA, ABD SONG F: Methods for Meta- Analysis in Medical Research. John Wiley & Sons Ltd., Chichester, UK. 2000.
15. HEDGES LV, OLKIN I: Statistical methods for meta-analysis. Academic Press, New York. 1985.
16. HIGGINS JPT, THOMPSON SG, DEEKS JJ et al.: Measuring inconsistency in meta-analyses BMJ 2003; 327: 557-60.
17. MATSUMO S, KANEDA K, NORHARA Y: Clinical evaluation of ketoprofen (orudis) in lumbago-a double blind comparison with diclofenac sodium. Br J Clin Pract 1981; 35: 266.
18. BOEY ML, RAE S, FENG PH: Comparison of efficacy of and tolerance to ketoprofen and diclofenac sodium in the treatment of rheumatoid arthritis. Singapore Med J 1988; 29: 240-5.
19. HYNNINEN MS, CHENG DC, HOSSAIN I et al.: Non-steroidal anti-inflammatory drugs in treatment of postoperative pain after cardiac surgery. Can J Anaesth 2000; 47: 1182-7.
20. CHERUBINO P: Effetto antalgico acuto ketoprofene sale lisina granulato in bustine verso diclofenac sodico compresse e placebo in pazienti affetti da lombalgia acuta di origine artrosica non traumatica. Studio in doppio cieco. Data on file Report KSB0194 1997.
21. TAI YM, BAKER R: Comparison of controlled- release ketoprofen and diclofenac in the control of post-surgical dental pain. J R Soc Med 1992; 85: 16-8.
22. CALIN A, BENNETT RM, SUKHUPUNYARAKSA S et al.: Double-blind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis. Rheumatol 1977; 4: 153-7.
23. GIACCAI L, MELANI F, PENGUE L: Results of a double-blind controlled study of the comparative effects of ketoprofen and ibuprofen in orthopedic patients. Clin Ter 1978; 84: 375- 85.
24. HUSKISSON EC, WOOLF DL, BALME HW, SCOTT J, FRANKLIN S: Four new anti-inflammatory drugs: responses and variations. Br Med J 1976; 1: 1048-9.
25. MEHLISCH DR: Ketoprofen, ibuprofen and placebo in the treatment of primary dysmenorrhea: a double-blind crossover comparison. Clin Pharmacol 1988; 28: S29-33.
26. MILLS SB, BLOCH M, BRUCKNER FE: Double- blind cross-over study of ketoprofen and ibuprofen in management of rheumatoid arthritis. Br Med J. 1973; 4: 82-4.
27. MONTRONE F, FUMAGALLI M, PELLEGRINI P et al.: A double-blind cross-over evaluation of ketoprofen (orudis) and ibuprofen in the management of rheumatoid arthritis. Rheumatol Rehabil 1979; 18: 114-8.
28. SAXENA RP, SAXENA U: A comparative trial of ketoprofen and ibuprofen in patients with rheumatic disease. Curr Med Res Opin 1978; 5: 484-8.
29. PANERAI AE: The management of paininflammatory conditions. Trends Med 2011; 11: 163-77.
30. LAPORTE JR, IBANEZ L, VIDAL X et al.: Upper gastrointestinal bleeding associated with the use of NSAIDs. Newer versus older agents. Drug Saf 2004; 27: 411-20.
31. LAPORTE JR, IBANEZ L, VIDAL X et al.: Upper gastrointestinal bleeding associated with the use of NSAIDs. Newer versus older agents. Drug Saf 2004; 27: 411-20.
32. http://department.obg.cuhk.edu.hk/researchsupport/ statstesthome.asp
33. BEGG CB, MAZUMDAR M: Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50: 1088- 101.
34. EGGER M, DAVEY SMITH G, SCHNEIDER M, MINDER C: Bias in metaanalysis detected by a simple, graphical test. BMJ 1997; 315: 629-34.
35. EGGER M, SMITH GD, PHILLIPS AN: Metaanalysis: principles and procedures. BMJ 1997; 315: 1533-7.
36. STERNE JAC, GAVAGHAN D, EGGER M: Publication and related bias in metaanalysis: power of statistical tests and prevalence in the literature. J Clin Epidemiol 2000;53: 1119-29.