Elastin-based molecular MRI of liver fibrosis

Hepatology

Volumn 58, Issue 4, 2013, Pages 1517-1518

  Ehling, Josef ^a   Bartneck, Matthias ^a   Fech, Viktor ^a   Butzbach, Britta ^b   Cesati, Richard ^c   Botnar, Rene ^b   Lammers, Twan ^a   Tacke, Frank ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Clinical Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; COLLAGEN; CONTRAST MEDIUM; ELASTIN; MACROPHAGE ELASTASE;

ATHEROSCLEROTIC PLAQUE; CONTRAST ENHANCEMENT; DISEASE COURSE; LETTER; LIVER FIBROSIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS;

ANIMALS; ELASTIN; LIVER CIRRHOSIS, EXPERIMENTAL; MACROPHAGES; MATRIX METALLOPROTEINASE 12;

EID: 84884954987     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26326     Document Type: Letter

References (4)

1. Iredale J. Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J Clin Invest 2007;117:539-548.
2. Pellicoro A, Aucott R, Ramachandran P, Robson A, Fallowfield J, Snowdon V, et al. Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis. Hepatology 2012;55:1965-1975.
3. Polasek M, Fuchs B, Uppal R, Schühle D, Alford J, Loving G, et al. Molecular MR imaging of liver fibrosis: A feasibility study using rat and mouse models. J Hepatol 2012;57:549-555.
4. Makowski M, Wiethoff A, Blume U, Cuello F, Warley A, Jansen C, et al. Assessment of atherosclerotic plaque burden with an elastin-specific magnetic resonance contrast agent. Nat Med 2011;17:383-388.