Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: A genetic meta-analysis

Osteoarthritis and Cartilage

Volumn 21, Issue 11, 2013, Pages 1700-1706

  Xing, D ^a   Ma, X L ^a   Ma, J X ^b   Xu, W G ^a   Wang, J ^b   Yang, Y ^a   Chen, Y ^a   Ma, B Y ^a   Zhu, S W ^a  

^a TIANJIN HOSPITAL   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Asporin; Knee; Meta analysis; Osteoarthritis; Polymorphism

Indexed keywords

ASPARTIC ACID; ASPN PROTEIN, HUMAN; SCLEROPROTEIN;

ARTICLE; ASIAN; CAUCASIAN; ETHNICITY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; KNEE OSTEOARTHRITIS; POPULATION GENETICS; PRIORITY JOURNAL; RACE DIFFERENCE; TANDEM REPEAT; ASIAN CONTINENTAL ANCESTRY GROUP; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; HUMAN; META ANALYSIS;

ASIAN CONTINENTAL ANCESTRY GROUP; ASPARTIC ACID; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXTRACELLULAR MATRIX PROTEINS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; OSTEOARTHRITIS, KNEE; POLYMORPHISM, GENETIC;

EID: 84884938654     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2013.08.005     Document Type: Article

References (27)

1. Poole A.R., Ionescu M., Swan A., Dieppe P.A. Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis. JClin Invest 1994, 94:25-33.
2. Lawrence R.C., Helmick C.G., Arnett F.C., Deyo R.A., Felson D.T., Giannini E.H., et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 1998, 41:778-799.
3. Lementowski P.W., Zelicof S.B. Obesity and osteoarthritis. Am J Orthop (Belle Mead NJ) 2008, 37:148-151.
4. Reid C.R., Bush P.M., Cummings N.H., McMullin D.L., Durrani S.K. Areview of occupational knee disorders. JOccup Rehabil 2010, 20:489-501.
5. Nevitt M.C., Felson D.T., Williams E.N., Grady D. The effect of estrogen plus progestin on knee symptoms and related disability in postmenopausal women: the Heart and Estrogen/Progestin Replacement Study, a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2001, 44:811-818.
6. Hunter D.J., March L., Sambrook P.N. Knee osteoarthritis: the influence of environmental factors. Clin Exp Rheumatol 2002, 20:93-100.
7. Peach C.A., Carr A.J., Loughlin J. Recent advances in the genetic investigation of osteoarthritis. Trends Mol Med 2005, 11:186-191.
8. Malemud C.J., Islam N., Haqqi T.M. Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies. Cells Tissues Organs 2003, 174:34-48.
9. Lorenzo P., Aspberg A., Onnerfjord P., Bayliss M.T., Neame P.J., Heinegard D. Identification and characterization of asporin. A novel member of the leucine-rich repeat protein family closely related to decorin and biglycan. JBiol Chem 2001, 276:12201-12211.
10. Henry S.P., Takanosu M., Boyd T.C., Mayne P.M., Eberspaecher H., Zhou W., et al. Expression pattern and gene characterization of asporin. A newly discovered member of the leucine-rich repeat protein family. JBiol Chem 2001, 276:12212-12221.
11. Duval E., Bigot N., Hervieu M., Kou I., Leclercq S., Galera P., et al. Asporin expression is highly regulated in human chondrocytes. Mol Med 2011, 17:816-823.
12. Kizawa H., Kou I., Iida A., Sudo A., Miyamoto Y., Fukuda A., et al. An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nat Genet 2005, 37:138-144.
13. Jiang Q., Shi D., Yi L., Ikegawa S., Wang Y., Nakamura T., et al. Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese. JHum Genet 2006, 51:1068-1072.
14. Rodriguez-Lopez J., Pombo-Suarez M., Liz M., Gomez-Reino J.J., Gonzalez A. Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians. Arthritis Res Ther 2006, 8:R55.
15. Kaliakatsos M., Tzetis M., Kanavakis E., Fytili P., Chouliaras G., Karachalios T., et al. Asporin and knee osteoarthritis in patients of Greek origin. Osteoarthritis Cartilage 2006, 14:609-611.
16. Mustafa Z., Dowling B., Chapman K., Sinsheimer J.S., Carr A., Loughlin J. Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population. Arthritis Rheum 2005, 52:3502-3506.
17. Robins J., Greenland S., Breslow N.E. Ageneral estimator for the variance of the Mantel-Haenszel odds ratio. Am J Epidemiol 1986, 124:719-723.
18. Egger M., Smith G.D., Phillips A.N. Meta-analysis: principles and procedures. BMJ 1997, 315:1533-1537.
19. Der Simonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7:177-188.
20. Higgins J.P., Thompson S.G. Quantifying heterogeneity in a meta-analysis. Stat Med 2002, 21:1539-1558.
21. Egger M., Davey S.G., Schneider M., Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
22. Begg C.B., Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994, 50:1088-1101.
23. Atif U., Philip A., Aponte J., Woldu E.M., Brady S., Kraus V.B., et al. Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. Osteoarthritis Cartilage 2008, 16:1174-1177.
24. Song J.H., Lee H.S., Kim C.J., Cho Y.G., Park Y.G., Nam S.W., et al. Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population. Knee 2008, 15:191-195.
25. Sakao K., Takahashi K.A., Arai Y., Saito M., Honjyo K., Hiraoka N., et al. Asporin and transforming growth factor-beta gene expression in osteoblasts from subchondral bone and osteophytes in osteoarthritis. JOrthop Sci 2009, 14:738-747.
26. Kou I., Nakajima M., Ikegawa S. Binding characteristics of the osteoarthritis-associated protein asporin. JBone Miner Metab 2010, 28:395-402.
27. Nakamura T., Shi D., Tzetis M., Rodriguez-Lopez J., Miyamoto Y., Tsezou A., et al. Meta-analysis of association between the ASPN D-repeat and osteoarthritis. Hum Mol Genet 2007, 16:1676-1681.