Stable deuterium internal standard for the isotope-dilution LC-MS/MS analysis of elastin degradation

Analytical Biochemistry

Volumn 440, Issue 2, 2013, Pages 158-165

  Ma, Shuren ^a   Turino, Gerard M ^a   Hayashi, Takahiro ^b   Yanuma, Hiroto ^b   Usuki, Toyonobu ^b   Lin, Yong Y ^a  

^a Columbia University College of Physicians ^*  (United States)

^b SOPHIA UNIVERSITY   (Japan)

Author keywords

Biomarkers of elastin degradation; Desmosine; Isodesmosine; Isotope dilution LC MS MS

Indexed keywords

CROSSLINKING; DEUTERIUM; DEUTERIUM COMPOUNDS; ELASTIN; GLYCOPROTEINS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULES; TISSUE; TISSUE ENGINEERING;

AMINO ACID SUBSTITUTION; BIOLOGICAL TISSUES; CROSS-LINKING MOLECULE; DESMOSINE; GENERALIZED METHOD; ISODESMOSINE; LC-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;

BIOMARKERS;

DESMOSINE; DEUTERIUM; ELASTIN; ISODESMOSINE;

AMINO ACID SUBSTITUTION; ARTICLE; ELASTIC TISSUE; HUMAN; HUMAN TISSUE; HYDROLYSIS; ISOTOPE DILUTION ASSAY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; SYNTHESIS; TANDEM MASS SPECTROMETRY;

BIOMARKERS OF ELASTIN DEGRADATION; DESMOSINE; DESMOSINE-D(4); ISODESMOSINE; ISOTOPE-DILUTION LC-MS/MS;

BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE; CHROMATOGRAPHY, LIQUID; DESMOSINE; DEUTERIUM; ELASTIN; HUMANS; ISODESMOSINE; PROTEOLYSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REFERENCE STANDARDS; TANDEM MASS SPECTROMETRY;

EID: 84884913470     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.05.014     Document Type: Article

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