Cell-free detection of allergen-IgE cross-linking with immobilized phase CD23: Inhibition by blocking antibody responses after immunotherapy

Journal of Allergy and Clinical Immunology

Volumn 132, Issue 4, 2013, Pages

  Shamji, Mohamed H ^a,d   Francis, James N ^a,d   Würtzen, Peter A ^b   Lund, Kaare ^b   Durham, Stephen R ^a,d   Till, Stephen J ^c,d  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ALK ABELLÓ   (Denmark)

^c GUY S HOSPITAL   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BIOTIN; BLOCKING ANTIBODY; CD23 ANTIGEN; IMMUNOGLOBULIN E; MONOMER;

ANTIBODY RESPONSE; B LYMPHOCYTE; CELL ASSAY; CELL SURFACE; ENZYME LINKED IMMUNOSORBENT ASSAY; GRASS POLLEN; HUMAN; IMMUNOTHERAPY; LETTER; PHLEUM PRATENSE; POLLEN ALLERGY; PREDICTIVE VALUE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; WESTERN BLOTTING;

EID: 84884906684     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.05.025     Document Type: Article

References (9)

1. P.A. Wachholz, N.K. Soni, S.J. Till, and S.R. Durham Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy J Allergy Clin Immunol 112 2003 915 922
2. M.H. Shamji, L.K. Wilcock, P.A. Wachholz, R.J. Dearman, I. Kimber, and P.A. Wurtzen The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses J Immunol Methods 317 2006 71 79
3. N. Willumsen, J. Holm, L.H. Christensen, P.A. Wurtzen, and K. Lund The complexity of allergic patients' IgE repertoire correlates with serum concentration of allergen-specific IgE Clin Exp Allergy 42 2012 1227 1236
4. J. Holm, N. Willumsen, P.A. Wurtzen, L.H. Christensen, and K. Lund Facilitated antigen presentation and its inhibition by blocking IgG antibodies depends on IgE repertoire complexity J Allergy Clin Immunol 127 2011 1029 1037
5. J.N. Francis, L.K. James, G. Paraskevopoulos, C. Wong, M.A. Calderon, and S.R. Durham Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity J Allergy Clin Immunol 121 2008 1120 1125
6. L.K. James, M.H. Shamji, S.M. Walker, D.R. Wilson, P.A. Wachholz, and J.N. Francis Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies J Allergy Clin Immunol 127 2011 509 516
7. M.H. Shamji, C. Ljorring, J.N. Francis, M.A. Calderon, M. Larche, and I. Kimber Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy Allergy 67 2012 217 226
8. R.G. Hibbert, P. Teriete, G.J. Grundy, R.L. Beavil, R. Reljic, and V.M. Holers The structure of human CD23 and its interactions with IgE and CD21 J Exp Med 202 2005 751 760
9. A.J. Frew, R.J. Powell, C.J. Corrigan, and S.R. Durham Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis J Allergy Clin Immunol 117 2006 319 325