Alternate day fasting with or without exercise: Effects on endothelial function and adipokines in obese humans

e-SPEN Journal

Volumn 8, Issue 5, 2013, Pages

  Bhutani, Surabhi ^a   Klempel, Monica C ^a   Kroeger, Cynthia M ^a   Trepanowski, J F ^a   Phillips, Shane A ^a   Norkeviciute, Edita ^a   Varady, Krista A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Adipokines; Alternate day fasting; Coronary heart disease; Endothelial function; Endurance exercise; Obese

Indexed keywords

ADIPONECTIN; LEPTIN;

ADULT; AGED; ARTERY BLOOD FLOW; ARTICLE; BODY WEIGHT; BRACHIAL ARTERY; CONTROLLED STUDY; DIET RESTRICTION; ENDOTHELIUM CELL; ENDURANCE; EXERCISE; FAT MASS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; RANDOMIZED CONTROLLED TRIAL;

EID: 84884900833     PISSN: None     EISSN: 22128263     Source Type: Journal    
DOI: 10.1016/j.clnme.2013.07.005     Document Type: Article

References (18)

1. Heilbronn L.K., Smith S.R., Martin C.K., Anton S.D., Ravussin E. Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism. Am J Clin Nutr 2005, 81:69-73.
2. Johnson J.B., Summer W., Cutler R.G., Martin B., Hyun D.H., Dixit V.D., et al. Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma. Free Radic Biol Med 2007, 42:665-674.
3. Varady K.A., Bhutani S., Church E.C., Klempel M.C. Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults. Am J Clin Nutr 2009, 90:1138-1143.
4. Bhutani S., Klempel M.C., Kroeger C.M., Trepanowski J.F., Varady K.A. Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans. Obesity (Silver Spring) 2013 Feb 14, [Epub ahead of print].
5. Inaba Y., Chen J.A., Bergmann S.R. Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int J Cardiovasc Imaging 2010, 26:631-640.
6. Plant S., Shand B., Elder P., Scott R. Adiponectin attenuates endothelial dysfunction induced by oxidised low-density lipoproteins. Diab Vasc Dis Res 2008, 5:102-108.
7. Goldstein B.J., Scalia R.G., Ma X.L. Protective vascular and myocardial effects of adiponectin. Nat Clin Pract Cardiovasc Med 2009, 6:27-35.
8. Korda M., Kubant R., Patton S., Malinski T. Leptin-induced endothelial dysfunction in obesity. Am J Physiol Heart Circ Physiol 2008, 295:H1514-H1521.
9. Bouassida A., Chamari K., Zaouali M., Feki Y., Zbidi A., Tabka Z. Review on leptin and adiponectin responses and adaptations to acute and chronic exercise. Br J Sports Med 2010, 44:620-630.
10. Mifflin M.D., St Jeor S.T., Hill L.A., Scott B.J., Daugherty S.A., Koh Y.O. Anew predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr 1990, 51:241-247.
11. Tanaka H., Monahan K.D., Seals D.R. Age-predicted maximal heart rate revisited. JAm Coll Cardiol 2001, 37:153-156.
12. Halberg N., Henriksen M., Soderhamn N., Stallknecht B., Ploug T., Schjerling P., et al. Effect of intermittent fasting and refeeding on insulin action in healthy men. JAppl Physiol 2005, 99:2128-2136.
13. Bhutani S., Klempel M.C., Berger R.A., Varady K.A. Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations. Obesity (Silver Spring) 2010, 18:2152-2159.
14. Hara T., Fujiwara H., Nakao H., Mimura T., Yoshikawa T., Fujimoto S. Body composition is related to increase in plasma adiponectin levels rather than training in young obese men. Eur J Appl Physiol 2005, 94:520-526.
15. Dharmashankar K., Widlansky M.E. Vascular endothelial function andhypertension: insights and directions. Curr Hypertens Rep 2010, 12:448-455.
16. Celermajer D.S., Sorensen K.E., Spiegelhalter D.J., Georgakopoulos D., Robinson J., Deanfield J.E. Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. JAm Coll Cardiol 1994, 24:471-476.
17. Tjonna A.E., Lee S.J., Rognmo O., Stolen T.O., Bye A., Haram P.M., et al. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation 2008, 118:346-354.
18. Ades P.A., Savage P.D., Lischke S., Toth M.J., Harvey-Berino J., Bunn J.Y., et al. The effect of weight loss and exercise training on flow-mediated dilatation in coronary heart disease: a randomized trial. Chest 2011, 140:1420-1427.