Single glutamate to aspartate mutation makes ferric uptake regulator (Fur) as sensitive to H2O2 as peroxide resistance regulator (PerR)

Angewandte Chemie - International Edition

Volumn 52, Issue 39, 2013, Pages 10339-10343

  Parent, Aubérie ^a,b,c   Caux Thang, Christelle ^a,b,c   Signor, Luca ^b,d   Clémancey, Martin ^a,b,c   Sethu, Ramakrishnan ^a,b,c   Blondin, Geneviève ^a,b,c   Maldivi, Pascale ^a   Duarte, Victor ^a,b,c   Latour, Jean Marc ^a,b,c  

^a UNIV GRENOBLE ALPES   (France)

^b CEA GRENOBLE   (France)

^c CNRS   (France)

^d INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

density functional calculations; ferric uptake regulator; M ssbauer spectroscopy; peroxide resistance regulator; peroxide stress

Indexed keywords

ASPARTATES; DFT CALCULATION; FE SENSORS; FERRIC UPTAKE REGULATOR; IN-VITRO; IN-VIVO; PEROXIDE STRESS; SSBAUER SPECTROSCOPIES;

DENSITY FUNCTIONAL THEORY; MASS SPECTROMETRY; PEROXIDES; SENSORS;

OXIDATION;

ASPARTIC ACID; BACTERIAL PROTEIN; FERRIC UPTAKE REGULATING PROTEINS, BACTERIAL; FERRIC UPTAKE REGULATOR; GLUTAMIC ACID; HYDROGEN PEROXIDE; PEROXIDE REPRESSOR PROTEINS; REPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM; CHEMICAL STRUCTURE; CHEMISTRY; DENSITY FUNCTIONAL CALCULATIONS; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOSSBAUER SPECTROSCOPY; MÖSSBAUER SPECTROSCOPY; PEROXIDE RESISTANCE REGULATOR; PEROXIDE STRESS; POINT MUTATION; SEQUENCE ALIGNMENT;

DENSITY FUNCTIONAL CALCULATIONS; FERRIC UPTAKE REGULATOR; MÖSSBAUER SPECTROSCOPY; PEROXIDE RESISTANCE REGULATOR; PEROXIDE STRESS;

AMINO ACID SEQUENCE; ASPARTIC ACID; BACTERIA; BACTERIAL PROTEINS; GLUTAMIC ACID; HUMANS; HYDROGEN PEROXIDE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; SPECTROSCOPY, MOSSBAUER;

EID: 84884852887     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201304021     Document Type: Article

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