Focal segmental glomerulosclerosis in children: Multivariate analysis indicates that donor type does not alter recurrence risk

Transplantation

Volumn 96, Issue 6, 2013, Pages 550-554

  Nehus, Edward J ^a   Goebel, Jens W ^a   Succop, Paul S ^b   Abraham, Elizabeth C ^c  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Donor type; Pediatric kidney transplant; Pediatric renal transplantation; Recurrent FSGS

Indexed keywords

ADOLESCENT; ADULT; AGE; ARTICLE; CADAVER KIDNEY; CAUCASIAN; CHILD; FEMALE; FOCAL GLOMERULOSCLEROSIS; HLA MATCHING; HUMAN; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RECURRENCE RISK; SCHOOL CHILD;

ADOLESCENT; AGE FACTORS; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; EUROPEAN CONTINENTAL ANCESTRY GROUP; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HISTOCOMPATIBILITY; HLA ANTIGENS; HUMANS; INFANT; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; LIVING DONORS; LOGISTIC MODELS; MULTIVARIATE ANALYSIS; ODDS RATIO; RECURRENCE; RISK FACTORS; SEX FACTORS; TIME FACTORS; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 84884821347     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31829c2431     Document Type: Article

References (28)

1. Ingulli E, Tejani A. Racial differences in the incidence and renal outcome of idiopathic focal segmental glomerulosclerosis in children. Pediatr Nephrol 1991; 5: 393.
2. Baum MA. Outcomes after renal transplantation for FSGS in children. Pediatr Transplant 2004; 8: 329.
3. Cameron SJ. Recurrent primary disease and de novo nephritis following renal transplantation. Pediatr Nephrol 1991; 5: 412.
4. Senggutuvan P, Cameron SJ, Hartely RB, et al. Recurrence of focal segmental glomerulosclerosis in transplanted kidneys: analysis of incidence and risk factors in 59 allografts. Pediatr Nephrol 1990; 4: 21.
5. First MR. Living related donor transplants should be performed with caution in patients with focal segmental glomerusclerosis. Pediatr Nephrol 1995; Suppl 9: S40.
6. Ponticelli C. Recurrence of focal segmental glomerulosclerosis (FSGS) after renal transplantation. Nephrol Dial Transplant 2010; 25: 25.
7. Butani L, Polinsky MS, Kaiser BA, et al. Predictive value of race in post-transplantation recurrence of focal segmental glomerulosclerosis in children. Nephrol Dial Transplant 1999; 14: 166.
8. Furth SL, Garg PP, Neu AM, et al. Racial differences in access to the kidney transplant waiting list for children and adolescents with endstage renal disease. Pediatrics 2000; 106: 756.
9. North American Pediatric Renal Trials and Collaborative Studies 2010 Annual Transplant Report. Exhibit 2.4: Donor Source by Age at Transplant.
10. Schachter AD, Harmon WE. Single-center analysis of early recurrence of nephrotic syndrome following renal transplantation in children. Pediatr Transplantation 2001; 5: 406.
11. Artero M, Biava C, Amend W, et al. Recurrent focal glomerulosclerosis: natural history and response to therapy. Am J Med 1992; 92: 375.
12. Striegel JE, Sibley RK, Fryd DS, et al. Recurrence of focal segmental sclerosis in children following renal transplantation. Kidney Int 1986; 30: S44.
13. Dall?Amico R, Ghigger G, Carraro M, et al. Prediction and treatment of recurrent focal segmental glomerulosclerosis after renal transplantation in children. Am J Kidney Dis 1999; 34: 1048.
14. Wuhl E, Fydryk J, Wiesel M, et al. Impact of recurrent nephrotic syndrome after renal transplantation in young patients. Pediatr Nephrol 1998; 12: 529.
15. Broyer M, Selwood N, Brunner F. Recurrence of primary renal disease on kidney graft: a European pediatric experience. J Am Soc Nephrol 1992; 2: S255.
16. Tejani A, Stablein D. Recurrence of focal segmental glomerulosclerosis posttransplantation: a special report of the North American Pediatric Renal Transplantation Cooperative Study. J Am Soc Nephrol 1992; 2: S258.
17. Baum MA, Stablein DM, Panzarino VM, et al. Loss of living donor renal allograft survival advantage in children with focal segmental glomerulosclerosis. Kidney Int 2001; 59: 328.
18. Huang K, Ferris ME, Andreoni KA, et al. The differential effect of race among pediatric kidney transplant recipients with focal segmental glomerulosclerosis. Am J Kidney Dis 2004; 43: 1082.
19. Abbott KC, Sawyers ES, Oliver JD, et al. Graft loss due to recurrent focal segmental glomerulosclerosis in renal transplant recipients in the United States. Am J Kidney Dis 2001; 37:366.
20. Mahesh S, Del Rio M, Fuerstein D, et al. Demographics and response to therapeutic plasma exchange in pediatric renal transplantation for focal glomerulosclerosis: a single center experience. Pediatr Transplant 2008; 12:682.
21. Hickson LJ, Gera M, Amer H, et al. Kidney transplantation for primary focal segmental glomerulosclerosis: outcomes and response to therapy for recurrence. Transplantation 2009; 87: 1232.
22. Savin VJ, Sharma R, Sharma M, et al. Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis. N Engl J Med 1996; 334: 878.
23. Savin VJ, McCarthy ET, Sharma R, et al. Galactose binds to focal segmental glomerulosclerosis permeability factor and inhibits its activity. Transl Res 2008; 151: 288.
24. Wei C, El Hindi S, Li J, et al. Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med 2011; 17: 952.
25. Kambham N, Markowitz GS, Valeri AM, et al. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int 2001; 59: 1498.
26. Bonilla-Felix M, Parra C, Dajani T, et al. Changing patterns in the histopathology of idiopathic nephrotic syndrome in children. Kidney Int 1999; 55: 1885.
27. Srivastava T, Simon SD, Alon US. High incidence of focal segmental glomerulosclerosis in nephrotic syndrome of childhood. Pediatr Nephrol 1999; 13: 13.
28. Based on OPTN data as of January 30, 2011.