Intraventricular fibrinolysis for severe aneurysmal intraventricular hemorrhage: A randomized controlled trial and meta-analysis

Neurosurgical Review

Volumn 36, Issue 4, 2013, Pages 523-531

  Litrico, Stephane ^a   Almairac, Fabien ^a   Gaberel, Thomas ^b,c   Ramakrishna, Rohan ^e   Fontaine, Denys ^a   Sedat, Jacques ^d   Lonjon, Michel ^a   Paquis, Philippe ^a  

^a PASTEUR HOSPITAL   (France)

^b CAEN UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE CAEN   (France)

^d University Hospital of Nice University of Nice Sophia Antipolis   (France)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Fibrinolytic agents; Intraventricular hemorrhage; Meta analysis; Randomized controlled trial; Subarachnoid hemorrhage; Tissue plasminogen activator

Indexed keywords

ALTEPLASE; ANTIBIOTIC AGENT;

ADULT; AGED; ARTICLE; BRAIN FOURTH VENTRICLE; BRAIN HEMORRHAGE; BRAIN THIRD VENTRICLE; BRAIN VASOSPASM; CENTRAL NERVOUS SYSTEM INFECTION; CLINICAL ARTICLE; COIL EMBOLIZATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; EXTERNAL VENTRICULAR DRAINAGE; FEMALE; FIBRINOLYSIS; FUNCTIONAL ASSESSMENT; HUMAN; HYDROCEPHALUS; MALE; MENINGITIS; META ANALYSIS; MORTALITY; NEUROSURGERY; OUTCOME ASSESSMENT; PATIENT SAFETY; PRIORITY JOURNAL; PSEUDOMONAS INFECTION; RANDOMIZED CONTROLLED TRIAL; SHUNTING; STAPHYLOCOCCUS INFECTION; SUBARACHNOID HEMORRHAGE; SURGICAL DRAINAGE; SURVIVAL RATE; TREATMENT DURATION;

ADULT; AGED; CEREBRAL VENTRICLES; ENDPOINT DETERMINATION; FEMALE; HUMANS; INTRACRANIAL ANEURYSM; INTRACRANIAL HEMORRHAGES; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NEUROIMAGING; ODDS RATIO; SURVIVAL ANALYSIS; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; VASOSPASM, INTRACRANIAL;

EID: 84884817024     PISSN: 03445607     EISSN: 14372320     Source Type: Journal    
DOI: 10.1007/s10143-013-0469-7     Document Type: Article

References (29)

1. Akdemir H, Selcuklu A, Pasaoglu A, Oktem IS, Kavuncu I (1995) Treatment of severe intraventricular hemorrhage by intraventricular infusion of urokinase. Neurosurg Rev 18(2):95-100
2. Ducruet AF, Hickman ZL, Zacharia BE, Grobelny BT, Narula R, Guo KH, Claassen J, Lee K, Badjatia N, Mayer SA, Connolly ES Jr (2010) Exacerbation of perihematomal edema and sterile meningitis with intraventricular administration of tissue plasminogen activator in patients with intracerebral hemorrhage. Neurosurgery 66(4):648-655. doi: 10.1227/01.NEU.0000360374.59435.60
3. Findlay JM, Grace MG, Weir BK (1993) Treatment of intraventricular hemorrhage with tissue plasminogen activator. Neurosurgery 32(6):941-947, discussion 947
4. Findlay JM, Jacka MJ (2004) Cohort study of intraventricular thrombolysis with recombinant tissue plasminogen activator for aneurysmal intraventricular hemorrhage. Neurosurgery 55(3):532-537, discussion 537-538
5. Gaberel T, Magheru C, Parienti JJ, Huttner HB, Vivien D, Emery E (2011) Intraventricular fibrinolysis versus external ventricular drainage alone in intraventricular hemorrhage: a meta-analysis. Stroke 42(10):2776-2781. doi: 10.1161/STROKEAHA.111.615724
6. Graeb DA, Robertson WD, Lapointe JS, Nugent RA, Harrison PB (1982) Computed tomographic diagnosis of intraventricular hemorrhage. Etiology and prognosis. Radiology 143(1):91-96
7. Hanley DF (2009) Intraventricular hemorrhage: severity factor and treatment target in spontaneous intracerebral hemorrhage. Stroke 40(4):1533-1538. doi: 10.1161/STROKEAHA.108.535419
8. Jennett B, Bond M (1975) Assessment of outcome after severe brain damage. Lancet 1(7905):480-484
9. Mayfrank L, Hutter BO, Kohorst Y, Kreitschmann-Andermahr I, Rohde V, Thron A, Gilsbach JM (2001) Influence of intraventricular hemorrhage on outcome after rupture of intracranial aneurysm. Neurosurg Rev 24(4):185-191
10. Morgan T, Awad I, Keyl P, Lane K, Hanley D (2008) Preliminary report of the clot lysis evaluating accelerated resolution of intraventricular hemorrhage (CLEAR-IVH) clinical trial. Acta Neurochir Suppl 105:217-220
11. Naff N, Williams MA, Keyl PM, Tuhrim S, Bullock MR, Mayer SA, Coplin W, Narayan R, Haines S, Cruz-Flores S, Zuccarello M, Brock D, Awad I, Ziai WC, Marmarou A, Rhoney D, McBee N, Lane K, Hanley DF Jr (2011) Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke 42(11):3009-3016. doi: 10.1161/STROKEAHA.110.610949
12. Naff NJ, Hanley DF, Keyl PM, Tuhrim S, Kraut M, Bederson J, Bullock R, Mayer SA, Schmutzhard E (2004) Intraventricular thrombolysis speeds blood clot resolution: results of a pilot, prospective, randomized, double-blind, controlled trial. Neurosurgery 54(3):577-583, discussion 583-574
13. Nieuwkamp DJ, de Gans K, Rinkel GJ, Algra A (2000) Treatment and outcome of severe intraventricular extension in patients with subarachnoid or intracerebral hemorrhage: a systematic review of the literature. J Neurol 247(2):117-121
14. O'Kelly CJ, Kulkarni AV, Austin PC, Urbach D, Wallace MC (2009) Shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage: incidence, predictors, and revision rates. Clinical article. J Neurosurg 111(5):1029-1035. doi: 10.3171/2008.9.JNS08881
15. Rainov NG, Burkert WL (1995) Urokinase infusion for severe intraventricular haemorrhage. Acta Neurochir (Wien) 134(1-2):55-59
16. Ramakrishna R, Sekhar LN, Ramanathan D, Temkin N, Hallam D, Ghodke BV, Kim LJ (2010) Intraventricular tissue plasminogen activator for the prevention of vasospasm and hydrocephalus after aneurysmal subarachnoid hemorrhage. Neurosurgery 67(1):110-117. doi: 10.1227/01.NEU.0000370920.44359.91, discussion 117
17. Rohde V, Schaller C, Hassler WE (1995) Intraventricular recombinant tissue plasminogen activator for lysis of intraventricular haemorrhage. J Neurol Neurosurg Psychiatry 58(4):447-451
18. Rosen DS, Macdonald RL, Huo D, Goldenberg FD, Novakovic RL, Frank JI, Rosengart AJ (2007) Intraventricular hemorrhage from ruptured aneurysm: clinical characteristics, complications, and outcomes in a large, prospective, multicenter study population. J Neurosurg 107(2):261-265. doi: 10.3171/JNS-07/08/0261
19. S.F.A.R. (2004) Hémorragie sous-arachnoidienne grave. Conférence d'experts. Société Française d'Anesthésie et de Réanimation, Paris
20. Schulz KF, Altman DG, Moher D (2010) CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol 63(8):834-840. doi: 10.1016/j.jclinepi.2010.02.005
21. Shen PH, Matsuoka Y, Kawajiri K, Kanai M, Hoda K, Yamamoto S, Nishimura S (1990) Treatment of intraventricular hemorrhage using urokinase. Neurol Med Chir (Tokyo) 30(5):329-333
22. Staykov D, Huttner HB, Struffert T, Ganslandt O, Doerfler A, Schwab S, Bardutzky J (2009) Intraventricular fibrinolysis and lumbar drainage for ventricular hemorrhage. Stroke 40(10):3275-3280. doi: 10.1161/STROKEAHA.109. 551945
23. Staykov D, Wagner I, Volbers B, Huttner HB, Doerfler A, Schwab S, Bardutzky J (2011) Dose effect of intraventricular fibrinolysis in ventricular hemorrhage. Stroke 42(7):2061-2064. doi: 10.1161/STROKEAHA.110.608190
24. Todo T, Usui M, Takakura K (1991) Treatment of severe intraventricular hemorrhage by intraventricular infusion of urokinase. J Neurosurg 74(1):81-86. doi: 10.3171/jns.1991.74.1.0081
25. Varelas PN, Rickert KL, Cusick J, Hacein-Bey L, Sinson G, Torbey M, Spanaki M, Gennarelli TA (2005) Intraventricular hemorrhage after aneurysmal subarachnoid hemorrhage: pilot study of treatment with intraventricular tissue plasminogen activator. Neurosurgery 56(2):205-213, discussion 205-213
26. Webb AJ, Ullman NL, Mann S, Muschelli J, Awad IA, Hanley DF (2012) Resolution of intraventricular hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: The Clot Lysis: Evaluating Accelerated Resolution of IVH (CLEAR IVH) Program. Stroke. doi: 10.1161/STROKEAHA.112.650523
27. Yepes M, Roussel BD, Ali C, Vivien D (2009) Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic. Trends Neurosci 32(1):48-55. doi: 10.1016/j.tins.2008.09.006
28. Yusuf S, Peto R, Lewis J, Collins R, Sleight P (1985) Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 27(5):335-371
29. Zacharia BE, Hickman ZL, Grobelny BT, DeRosa P, Kotchetkov I, Ducruet AF, Connolly ES Jr (2010) Epidemiology of aneurysmal subarachnoid hemorrhage. Neurosurg Clin N Am 21(2):221-233. doi: 10.1016/j.nec.2009.10.002