-
1
-
-
77950976702
-
Disrupting established tumor blood vessels: An emerging therapeutic strategy for cancer
-
20166210 10.1002/cncr.24975 1:CAS:528:DC%2BC3cXlvVGlsbk%3D
-
McKeage MJ, Baguley BC (2010) Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer. Cancer 116:1859-1871
-
(2010)
Cancer
, vol.116
, pp. 1859-1871
-
-
McKeage, M.J.1
Baguley, B.C.2
-
2
-
-
70349338935
-
Ave8062: A new combretastatin derivative vascular disrupting agent
-
19758109 10.1517/13543780903213697 1:CAS:528:DC%2BD1MXhtFCisLbO
-
Delmonte A, Sessa C (2009) Ave8062: a new combretastatin derivative vascular disrupting agent. Expert Opin Investig Drugs 18:1541-1548
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1541-1548
-
-
Delmonte, A.1
Sessa, C.2
-
3
-
-
77956265269
-
Perfusion mri in the early clinical development of antivascular drugs: Decorations or decision making tools?
-
20461374 10.1007/s00259-010-1451-z
-
Zweifel M, Padhani AR (2010) Perfusion mri in the early clinical development of antivascular drugs: decorations or decision making tools? Eur J Nucl Med Mol Imaging 37(Suppl 1):S164-S182
-
(2010)
Eur J Nucl Med Mol Imaging
, vol.37
, Issue.SUPPL. 1
-
-
Zweifel, M.1
Padhani, A.R.2
-
4
-
-
80051769183
-
Multiparametric mri biomarkers for measuring vascular disrupting effect on cancer
-
21286490 10.4329/wjr.v3.i1.1
-
Wang H, Marchal G, Ni Y (2011) Multiparametric mri biomarkers for measuring vascular disrupting effect on cancer. World J Radiol 3:1-16
-
(2011)
World J Radiol
, vol.3
, pp. 1-16
-
-
Wang, H.1
Marchal, G.2
Ni, Y.3
-
5
-
-
77957942570
-
Morphological, functional and metabolic imaging biomarkers: Assessment of vascular-disrupting effect on rodent liver tumours
-
20182730 10.1007/s00330-010-1743-5
-
Wang H, Li J, Chen F, De Keyzer F, Yu J, Feng Y, Nuyts J, Marchal G, Ni Y (2010) Morphological, functional and metabolic imaging biomarkers: assessment of vascular-disrupting effect on rodent liver tumours. Eur Radiol 20:2013-2026
-
(2010)
Eur Radiol
, vol.20
, pp. 2013-2026
-
-
Wang, H.1
Li, J.2
Chen, F.3
De Keyzer, F.4
Yu, J.5
Feng, Y.6
Nuyts, J.7
Marchal, G.8
Ni, Y.9
-
6
-
-
77956336496
-
Discovery of a potent tubulin polymerization inhibitor: Synthesis and evaluation of water-soluble prodrugs of benzophenone analog
-
20850313 10.1016/j.bmcl.2010.05.060 1:CAS:528:DC%2BC3cXht1KrsbbJ
-
Lee J, Bae S, Lee SH, Choi H, Kim YH, Kim SJ, Park GT, Moon SK, Kim DH, Lee S, Ahn SK, Choi NS, Lee KJ (2010) Discovery of a potent tubulin polymerization inhibitor: synthesis and evaluation of water-soluble prodrugs of benzophenone analog. Bioorg Med Chem Lett 20:6327-6330
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 6327-6330
-
-
Lee, J.1
Bae, S.2
Lee, S.H.3
Choi, H.4
Kim, Y.H.5
Kim, S.J.6
Park, G.T.7
Moon, S.K.8
Kim, D.H.9
Lee, S.10
Ahn, S.K.11
Choi, N.S.12
Lee, K.J.13
-
7
-
-
77956298509
-
Identification of ckd-516: A potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors
-
20690624 10.1021/jm1002414 1:CAS:528:DC%2BC3cXpvVaqsbs%3D
-
Lee J, Kim SJ, Choi H, Kim YH, Lim IT, Yang HM, Lee CS, Kang HR, Ahn SK, Moon SK, Kim DH, Lee S, Choi NS, Lee KJ (2010) Identification of ckd-516: a potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors. J Med Chem 53:6337-6354
-
(2010)
J Med Chem
, vol.53
, pp. 6337-6354
-
-
Lee, J.1
Kim, S.J.2
Choi, H.3
Kim, Y.H.4
Lim, I.T.5
Yang, H.M.6
Lee, C.S.7
Kang, H.R.8
Ahn, S.K.9
Moon, S.K.10
Kim, D.H.11
Lee, S.12
Choi, N.S.13
Lee, K.J.14
-
8
-
-
80555148208
-
Vascular effects dominate solid tumor response to treatment with combretastatin a-4-phosphate
-
Lunt SJ, Akerman S, Hill SA, Fisher M, Wright VJ, Reyes-Aldasoro CC, Tozer GM, Kanthou C (2010) Vascular effects dominate solid tumor response to treatment with combretastatin a-4-phosphate. Int J Cancer
-
(2010)
Int J Cancer
-
-
Lunt, S.J.1
Akerman, S.2
Hill, S.A.3
Fisher, M.4
Wright, V.J.5
Reyes-Aldasoro, C.C.6
Tozer, G.M.7
Kanthou, C.8
-
9
-
-
84951606693
-
A transplantable rabbit carcinoma originating in a virus-induced papilloma and containing the virus in masked or altered form
-
19871000 10.1084/jem.71.6.813 1:STN:280:DC%2BC3crjs1Kjtg%3D%3D
-
Kidd JG, Rous P (1940) A transplantable rabbit carcinoma originating in a virus-induced papilloma and containing the virus in masked or altered form. J Exp Med 71:813-838
-
(1940)
J Exp Med
, vol.71
, pp. 813-838
-
-
Kidd, J.G.1
Rous, P.2
-
10
-
-
0026011540
-
Measurement of the blood-brain barrier permeability and leakage space using dynamic mr imaging. 1. Fundamental concepts
-
2062210 10.1002/mrm.1910170208 1:STN:280:DyaK3M3oslGiug%3D%3D
-
Tofts PS, Kermode AG (1991) Measurement of the blood-brain barrier permeability and leakage space using dynamic mr imaging. 1. Fundamental concepts. Magn Reson Med 17:357-367
-
(1991)
Magn Reson Med
, vol.17
, pp. 357-367
-
-
Tofts, P.S.1
Kermode, A.G.2
-
11
-
-
0032828135
-
Estimating kinetic parameters from dynamic contrast-enhanced t(1)-weighted mri of a diffusable tracer: Standardized quantities and symbols
-
10508281 10.1002/(SICI)1522-2586(199909)10:3<223: AID-JMRI2>3.0. CO;2-S 1:STN:280:DyaK1Mvjsl2jtw%3D%3D
-
Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, Larsson HB, Lee TY, Mayr NA, Parker GJ, Port RE, Taylor J, Weisskoff RM (1999) Estimating kinetic parameters from dynamic contrast-enhanced t(1)-weighted mri of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 10:223-232
-
(1999)
J Magn Reson Imaging
, vol.10
, pp. 223-232
-
-
Tofts, P.S.1
Brix, G.2
Buckley, D.L.3
Evelhoch, J.L.4
Henderson, E.5
Knopp, M.V.6
Larsson, H.B.7
Lee, T.Y.8
Mayr, N.A.9
Parker, G.J.10
Port, R.E.11
Taylor, J.12
Weisskoff, R.M.13
-
12
-
-
0032879415
-
Tumour vascularity and proliferation: Clear evidence of a close relationship
-
10547589 10.1002/(SICI)1096-9896(199911)189:3<297: AID-PATH434>3.0.CO;2-O 1:STN:280:DC%2BD3c%2Fhs1CnsQ%3D%3D
-
Weidner N (1999) Tumour vascularity and proliferation: clear evidence of a close relationship. J Pathol 189:297-299
-
(1999)
J Pathol
, vol.189
, pp. 297-299
-
-
Weidner, N.1
-
13
-
-
64949141660
-
Quantification of angiogenesis by ct perfusion imaging in liver tumor of rabbit
-
19357031
-
Jiang HJ, Zhang ZR, Shen BZ, Wan Y, Guo H, Li JP (2009) Quantification of angiogenesis by ct perfusion imaging in liver tumor of rabbit. Hepatobiliary Pancreat Dis Int 8:168-173
-
(2009)
Hepatobiliary Pancreat Dis Int
, vol.8
, pp. 168-173
-
-
Jiang, H.J.1
Zhang, Z.R.2
Shen, B.Z.3
Wan, Y.4
Guo, H.5
Li, J.P.6
-
14
-
-
80555131123
-
Effects of the novel vascular targeting agent mds-11p on tumor vascularity and its antitumor activity
-
21920350 10.1016/j.bcp.2011.08.024 1:CAS:528:DC%2BC3MXhsVaqsb3E
-
Deng ZT, Feng T, Wang P, Qi X, Chen XH, Li YX, Song CL, Geng MY, Li J (2011) Effects of the novel vascular targeting agent mds-11p on tumor vascularity and its antitumor activity. Biochem Pharmacol 82:1832-1842
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1832-1842
-
-
Deng, Z.T.1
Feng, T.2
Wang, P.3
Qi, X.4
Chen, X.H.5
Li, Y.X.6
Song, C.L.7
Geng, M.Y.8
Li, J.9
-
15
-
-
0037115398
-
Zd6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature
-
12499266 1:CAS:528:DC%2BD3sXhtVyqtA%3D%3D
-
Davis PD, Dougherty GJ, Blakey DC, Galbraith SM, Tozer GM, Holder AL, Naylor MA, Nolan J, Stratford MR, Chaplin DJ, Hill SA (2002) Zd6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature. Cancer Res 62:7247-7253
-
(2002)
Cancer Res
, vol.62
, pp. 7247-7253
-
-
Davis, P.D.1
Dougherty, G.J.2
Blakey, D.C.3
Galbraith, S.M.4
Tozer, G.M.5
Holder, A.L.6
Naylor, M.A.7
Nolan, J.8
Stratford, M.R.9
Chaplin, D.J.10
Hill, S.A.11
-
16
-
-
0037223457
-
Microfilaments and microtubules maintain endothelial integrity
-
12500268 10.1002/jemt.10250 1:CAS:528:DC%2BD3sXmvVSmuw%3D%3D
-
Lee TY, Gotlieb AI (2003) Microfilaments and microtubules maintain endothelial integrity. Microsc Res Tech 60:115-127
-
(2003)
Microsc Res Tech
, vol.60
, pp. 115-127
-
-
Lee, T.Y.1
Gotlieb, A.I.2
-
17
-
-
0036568457
-
Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
-
11948484 10.1002/ijc.10316 1:CAS:528:DC%2BD38XivVCgsr4%3D
-
Siemann DW, Mercer E, Lepler S, Rojiani AM (2002) Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int J Cancer 99:1-6
-
(2002)
Int J Cancer
, vol.99
, pp. 1-6
-
-
Siemann, D.W.1
Mercer, E.2
Lepler, S.3
Rojiani, A.M.4
-
18
-
-
79953741443
-
A perspective on vascular disrupting agents that interact with tubulin: Preclinical tumor imaging and biological assessment
-
10.1039/c0ib00135j 1:CAS:528:DC%2BC3MXlvFyms7w%3D
-
Mason RP, Zhao D, Liu L, Trawick ML, Pinney KG (2011) A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment. Integr Biol (Camb) 3:375-387
-
(2011)
Integr Biol (Camb)
, vol.3
, pp. 375-387
-
-
Mason, R.P.1
Zhao, D.2
Liu, L.3
Trawick, M.L.4
Pinney, K.G.5
-
19
-
-
48249103089
-
Relationship between human tumour angiogenic profile and combretastatin-induced vascular shutdown: An exploratory study
-
18612312 10.1038/sj.bjc.6604426 1:CAS:528:DC%2BD1cXosFWnsb4%3D
-
Gaya A, Daley F, Taylor NJ, Tozer G, Qureshi U, Padhani A, Pedley RB, Begent R, Wellsted D, Stirling JJ, Rustin G (2008) Relationship between human tumour angiogenic profile and combretastatin-induced vascular shutdown: an exploratory study. Br J Cancer 99:321-326
-
(2008)
Br J Cancer
, vol.99
, pp. 321-326
-
-
Gaya, A.1
Daley, F.2
Taylor, N.J.3
Tozer, G.4
Qureshi, U.5
Padhani, A.6
Pedley, R.B.7
Begent, R.8
Wellsted, D.9
Stirling, J.J.10
Rustin, G.11
-
20
-
-
38149029566
-
Early quantitative evaluation of a tumor vasculature disruptive agent ave8062 using dynamic contrast-enhanced ultrasonography
-
18197062 10.1097/RLI.0b013e3181577cfc 1:CAS:528:DC%2BD1cXmt1Kqtw%3D%3D
-
Lavisse S, Lejeune P, Rouffiac V, Elie N, Bribes E, Demers B, Vrignaud P, Bissery MC, Brule A, Koscielny S, Peronneau P, Lassau N (2008) Early quantitative evaluation of a tumor vasculature disruptive agent ave8062 using dynamic contrast-enhanced ultrasonography. Invest Radiol 43:100-111
-
(2008)
Invest Radiol
, vol.43
, pp. 100-111
-
-
Lavisse, S.1
Lejeune, P.2
Rouffiac, V.3
Elie, N.4
Bribes, E.5
Demers, B.6
Vrignaud, P.7
Bissery, M.C.8
Brule, A.9
Koscielny, S.10
Peronneau, P.11
Lassau, N.12
-
21
-
-
67249084753
-
Abt-751, a novel tubulin-binding agent, decreases tumor perfusion and disrupts tumor vasculature
-
19398903 10.1097/CAD.0b013e32832c0acf 1:CAS:528:DC%2BD1MXnt12qt7g%3D
-
Luo Y, Hradil VP, Frost DJ, Rosenberg SH, Gordon GB, Morgan SJ, Gagne GD, Cox BF, Tahir SK, Fox GB (2009) Abt-751, a novel tubulin-binding agent, decreases tumor perfusion and disrupts tumor vasculature. Anticancer Drugs 20:483-492
-
(2009)
Anticancer Drugs
, vol.20
, pp. 483-492
-
-
Luo, Y.1
Hradil, V.P.2
Frost, D.J.3
Rosenberg, S.H.4
Gordon, G.B.5
Morgan, S.J.6
Gagne, G.D.7
Cox, B.F.8
Tahir, S.K.9
Fox, G.B.10
-
22
-
-
63449111973
-
Treatment of rodent liver tumor with combretastatin a4 phosphate: Noninvasive therapeutic evaluation using multiparametric magnetic resonance imaging in correlation with microangiography and histology
-
19034028 10.1097/RLI.0b013e31818e5ace 1:CAS:528:DC%2BD1MXht1ent7o%3D
-
Wang H, Sun X, Chen F, De Keyzer F, Yu J, Landuyt W, Vandecaveye V, Peeters R, Bosmans H, Hermans R, Marchal G, Ni Y (2009) Treatment of rodent liver tumor with combretastatin a4 phosphate: noninvasive therapeutic evaluation using multiparametric magnetic resonance imaging in correlation with microangiography and histology. Invest Radiol 44:44-53
-
(2009)
Invest Radiol
, vol.44
, pp. 44-53
-
-
Wang, H.1
Sun, X.2
Chen, F.3
De Keyzer, F.4
Yu, J.5
Landuyt, W.6
Vandecaveye, V.7
Peeters, R.8
Bosmans, H.9
Hermans, R.10
Marchal, G.11
Ni, Y.12
-
23
-
-
27644466314
-
Combretastatin a4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling
-
16224539 10.1172/JCI24586 1:CAS:528:DC%2BD2MXhtF2kt73M
-
Vincent L, Kermani P, Young LM, Cheng J, Zhang F, Shido K, Lam G, Bompais-Vincent H, Zhu Z, Hicklin DJ, Bohlen P, Chaplin DJ, May C, Rafii S (2005) Combretastatin a4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. J Clin Investig 115:2992-3006
-
(2005)
J Clin Investig
, vol.115
, pp. 2992-3006
-
-
Vincent, L.1
Kermani, P.2
Young, L.M.3
Cheng, J.4
Zhang, F.5
Shido, K.6
Lam, G.7
Bompais-Vincent, H.8
Zhu, Z.9
Hicklin, D.J.10
Bohlen, P.11
Chaplin, D.J.12
May, C.13
Rafii, S.14
|