Quantification of angiogenesis by CT perfusion imaging in liver tumor of rabbit

Hepatobiliary and Pancreatic Diseases International

Volumn 8, Issue 2, 2009, Pages 168-173

  Jiang, Hui Jie ^a   Zhang, Zai Ren ^a   Shen, Bao Zhong ^a   Wan, Yong ^a   Guo, Hong ^a   Li, Jin Ping ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Animal model; Immunohistochemistry; Liver neoplasms; Perfusion imaging

Indexed keywords

CD34 ANTIBODY; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VOLUME; CAPILLARY PERMEABILITY; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY PERFUSION; CONTROLLED STUDY; HEPATIC ARTERY; IMMUNOHISTOCHEMISTRY; LIVER BLOOD FLOW; LIVER PERFUSION; LIVER TUMOR; MULTIDETECTOR COMPUTED TOMOGRAPHY; NONHUMAN; RABBIT;

ANIMALS; LIVER NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; RABBITS; TOMOGRAPHY, X-RAY COMPUTED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 64949141660     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Li WW. Tumor angiogenesis:. molecular pathology, therapeutic targeting, and imaging. Acad Radiol 2000;7: 800-811.
2. Brasch RC, Li KC, Husband JE, Keogan MT, Neeman M, Padhani AR, et al. In vivo monitoring of tumor angiogenesis with MR imaging. Acad Radiol 2000;7:812-823.
3. Miles KA, Charnsangavej C, Lee FT, Fishman EK, Horton K, Lee TY. Application of CT in the investigation of angiogenesis in oncology. Acad Radiol 2000;7:840-850.
4. Cheng HL. Dynamic contrast-enhanced MRI in oncology drug development. Curr Clin Pharmacol 2007;2:111-122.
5. Kaneoya K, Ueda T, Suito H, Nanazawa Y, Tamaru J, Isobe K, et al. Functional computed tomography imaging of tumor-induced angiogenesis: preliminary results of new tracer kinetic modeling using a computer discretization approach. Radiat Med 2008;26:213-221.
6. Schmidt K, Hoffend J, Altmann A, Kiessling F, Strauss L, Koczan D, et al. Troponin I overexpression inhibits tumor growth, perfusion, and vascularization of morris hepatoma. J Nucl Med 2006;47:1506-1514.
7. Weidner N. Tumour vascularity and proliferation: clear evidence of a close relationship. J Pathol 1999;189:297-299.
8. Parkin A, Goldstone KE, Robinson PJ. Hepatic perfusion index measured using MRI and scintigraphy. Br J Radiol 2005;78:1118-1119.
9. Artiko V, Obradovic V, Petrovic M, Perisic M, Stojkovic M, Sobic-Saranovic D, et al. Hepatic radionuclide angiography and Doppler ultrasonography in the detection and assessment of vascular disturbances in the portal system. Hepatogastroenterology 2007;54:892-897.
10. Iozzo P, Jarvisalo MJ, Kiss J, Borra R, Naum GA, Viljanen A, et al. Quantification of liver glucose metabolism by positron emission tomography: validation study in pigs. Gastroenterology 2007;132:531-542.
11. Bonnin P, Villemain A, Vincent F, Debbabi H, Silvestre JS, Contreres JO, et al. Ultrasonic assessment of hepatic blood flow as a marker of mouse hepatocarcinoma. Ultrasound Med Biol 2007;33:561-570.
12. Pandharipande PV, Krinsky GA, Rusinek H, Lee VS. Perfusion imaging of the liver: current challenges and future goals. Radiology 2005;234:661-673.
13. Wang J, Chen LT, Tsang YM, Liu TW, Shih TT. Dynamic contrast-enhanced MRI analysis of perfusion changes in advanced hepatocellular carcinoma treated with an antiangiogenic agent: a preliminary study. AJR Am J Roentgenol 2004;183:713-719.
14. Stewart EE, Chen X, Hadway J, Lee TY. Correlation between hepatic tumor blood flow and glucose utilization in a rabbit liver tumor model. Radiology 2006;239:740-750.
15. Maruyama H, Matsutani S, Saisho H, Kamiyama N, Mine Y, Hirata T, et al. Sonographic shift of hypervascular liver tumor on blood pool harmonic images with definity: time-related changes of contrast-enhanced appearance in rabbit VX2 tumor under extra-low acoustic power. Eur J Radiol 2005;56:60-65.
16. Kan Z, Phongkitkarun S, Kobayashi S, Tang Y, Ellis LM, Lee TY, et al. Functional CT for quantifying tumor perfusion in antiangiogenic therapy in a rat model. Radiology 2005;237:151-158.
17. Matsubayashi R, Matsuo Y, Edakuni G, Satoh T, Tokunaga O, Kudo S. Breast masses with peripheral rim enhancement on dynamic contrast-enhanced MR images: correlation of MR findings with histologic features and expression of growth factors. Radiology 2000;217:841-848.
18. Ogawa M, Yamamoto H, Nagano H, Miyake Y, Sugita Y, Hata T, et al. Hepatic expression of ANG2 RNA in metastatic colorectal cancer. Hepatology 2004;39:528-539.
19. Pruneri G, Ponzoni M, Ferreri AJ, Decarli N, Tresoldi M, Raggi F, et al. Microvessel density, a surrogate marker of angiogenesis, is significantly related to survival in multiple myeloma patients. Br J Haematol 2002;118:817-820.
20. Leen E, Goldberg JA, Anderson JR, Robertson J, Moule B, Cooke TG, et al. Hepatic perfusion changes in patients with liver metastases: comparison with those patients with cirrhosis. Gut 1993;34:554-557.
21. Tsushima Y, Blomley JK, Kusano S, Endo K. The portal component of hepatic perfusion measured by dynamic CT: an indicator of hepatic parenchymal damage. Dig Dis Sci 1999;44:1632-1638.
22. Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained with dynamic CT. Radiology 1993;188:405-411.
23. Ippolito D, Sironi S, Pozzi M, Antolini L, Ratti L, Alberzoni C, et al. Hepatocellular carcinoma in cirrhotic liver disease: functional computed tomography with perfusion imaging in the assessment of tumor vascularization. Acad Radiol 2008;15:919-927.
24. Sahani DV, Holalkere NS, Mueller PR, Zhu AX. Advanced hepatocellular carcinoma: CT perfusion of liver and tumor tissue--initial experience. Radiology 2007;243:736-743.
25. Tsushima Y, Funabasama S, Aoki J, Sanada S, Endo K. Quantitative perfusion map of malignant liver tumors, created from dynamic computed tomography data. Acad Radiol 2004;11:215-223.
26. Gately S, Kerbel R. Antiangiogenic scheduling of lower dose cancer chemotherapy. Cancer J 2001;7:427-436.
27. Harvey C, Dooher A, Morgan J, Blomley M, Dawson P. Imaging of tumour therapy responses by dynamic CT. Eur J Radiol 1999;30:221-226.
28. Sabir A, Schor-Bardach R, Wilcox CJ, Rahmanuddin S, Atkins MB, Kruskal JB, et al. Perfusion MDCT enables early detection of therapeutic response to antiangiogenic therapy. AJR Am J Roentgenol 2008;191:133-139.
29. Pollard RE, Broumas AR, Wisner ER, Vekich SV, Ferrara KW. Quantitative contrast enhanced ultrasound and CT assessment of tumor response to antiangiogenic therapy in rats. Ultrasound Med Biol 2007;33:235-245.