Native human interferon-α is a strong inductor of endogenous cytokines involved in the suppression of procollagen type I

Biomedicine and Pharmacotherapy

Volumn 67, Issue 7, 2013, Pages 665-668

  Santak G ^a   Santak M ^b   Forcic D ^b  

^a Po ega General Hospital   (Croatia)

^b INSTITUTE OF IMMUNOLOGY   (Croatia)

Author keywords

Endogenous interferons; Interferon ; Native human interferon ; Procollagen type I

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 1BETA; MESSENGER RNA; PROCOLLAGEN;

ARTICLE; CELL CULTURE; CHEMICAL REACTION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ENDOGENOUS INTERFERONS; INTERFERON-Γ; NATIVE HUMAN INTERFERON-Α; PROCOLLAGEN TYPE I;

COLLAGEN TYPE I; CYCLOHEXIMIDE; CYTOKINES; GENE EXPRESSION; HUMANS; INTERFERON-ALPHA; INTERFERONS; INTERLEUKIN-1BETA; PROCOLLAGEN; RECOMBINANT PROTEINS;

EID: 84884812438     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2013.03.003     Document Type: Article

References (15)

1. Taniguchi T., Takaoka A. The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 2002, 14:111-116.
2. Takaoka A., Taniguchi T. New aspects of IFN-alpha/beta signalling in immunity, oncogenesis and bone metabolism. Cancer Sci 2003, 94:405-411.
3. Kotenko S.V., Gallagher G., Baurin V.V., Lewis-Antes A., Shen M., Shah N.K., et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol 2003, 4:69-77.
4. Nyman T.A., Tolo H., Parkkinen J., Kalkkinen N. Identification of nine interferon-α subtypes produced by Sendai virus induced human peripheral blood leucocytes. Biochem J 1998, 329:295-302.
5. Židovec S., Mažuran R. Sendai virus induces various cytokines in human peripheral blood leukocytes: different susceptibility of cytokine molecules to low pH. Cytokine 1999, 11:140-143.
6. Paquette R.L., Hsu N.C., Kiertscher S.M., Park A.N., Tran L., Roth M.D., et al. Interferon-alpha and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells. J Leukoc Biol 1998, 64:358-367.
7. Bailon P., Palleroni A., Schaffer C.A., Spence C.L., Fung W.J., Porter J.E., et al. Rational design of a potent, long-lasting form of interferon: a 40kDa branched polyethylene glycol-conjugated interferon r-2a for the treatment of hepatitis C. Bioconjugate Chem 2001, 12:195-202.
8. Upreti M., Koonce N.A., Hennings L., Chambers T.C., Griffin R.J. Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1 mediated signaling. Cell Death Dis 2010, 1:67.
9. Šantak G., Šantak M., Forčić D. Native human IFN-alpha is a more potent suppressor of HDF response to profibrotic stimuli than recombinant human IFN-alpha. J Interferon Cytokine Res 2007, 27:481-490.
10. Šantak G., Šantak M., Forčić D. The role of interleukin-1beta and platelet-derived growth factor-AB in antifibrosis mediated by native human interferon alpha. Surgery 2010, 148:490-498.
11. Jimenez S.A., Freundlich B., Rosenbloom J. Selective inhibition of human diploid fibroblast collagen synthesis by interferons. J Clin Invest 1984, 74:1112-1116.
12. Okamura H., Kashiwamura S., Tsutsui H., Yoshimoto T., Nakanishi K. Regulation of interferon-gamma production by IL-12 and IL-18. Curr Opin Immunol 1998, 10:259-264.
13. Haller O., Kochs G., Weber F. Interferon, Mx, and viral countermeasures. Cytokine Growth Factor Rev 2007, 18:425-433.
14. Lankford C.S., Frucht D.M. A unique role for IL-23 in promoting cellular immunity. J Leukoc Biol 2003, 73:49-56.
15. Malmgaard L., Paludan S.R. Interferon (IFN)-alpha/beta, interleukin (IL)-12 and IL-18 coordinately induce production of IFN-gamma during infection with herpes simplex virus type 2. J Gen Virol 2003, 84:2497-2500.