Mice with a targeted disruption of Slc4a11 model the progressive corneal changes of congenital hereditary endothelial dystrophy

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 9, 2013, Pages 6179-6189

  Han, Sang Beom ^a,b,c   Ang, Heng Pei ^b   Poh, Rebekah ^b   Chaurasia, Shyam S ^b,d,e   Peh, Gary ^b   Liu, Jun ^b   Tan, Donald T H ^a,b,e   Vithana, Eranga N ^b,d,e   Mehta, Jodhbir S ^a,b,e,f  

^a SINGAPORE NATIONAL EYE CENTRE   (Singapore)

^b SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^c Sungkyunkwan University School of Medicine   (South Korea)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^f DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Animal model; Congenital hereditary endothelial dystrophy; Corneal endothelial dystrophy; Slc4a11

Indexed keywords

AQUAPORIN 1; COLLAGEN TYPE 1; COLLAGEN TYPE 6; COLLAGEN TYPE 8; FIBRONECTIN; LAMININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SWELLING; CONGENITAL CORNEA DYSTROPHY; CORNEA EDEMA; CORNEA THICKNESS; ELECTROLYTE URINE LEVEL; GENE; GENE DELETION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUSE; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PHOTOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SLC4A11 GENE; URINE OSMOLALITY;

ANIMAL MODEL; CONGENITAL HEREDITARY ENDOTHELIAL DYSTROPHY; CORNEAL ENDOTHELIAL DYSTROPHY; SLC4A11;

ANIMALS; ANION TRANSPORT PROTEINS; CELL COUNT; CORNEAL DYSTROPHIES, HEREDITARY; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA; ENDOTHELIUM, CORNEAL; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; REAL-TIME POLYMERASE CHAIN REACTION; SYMPORTERS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84884810616     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12089     Document Type: Article

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