Opportunity to monitor immunosuppressive drugs in peripheral blood mononuclear cells: Where are we and where are we going?

Pharmacological Research

Volumn 74, Issue , 2013, Pages 109-112

  Lemaitre, Florian ^a,b,c,d   Antignac, Marie ^d,e   Verdier, Marie Clémence ^a,b,c   Bellissant, Eric ^a,b,c   Fernandez, Christine ^d,e  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

^d EA4123   (France)

^e ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Immunosuppressive drug; Intracellular; Peripheral blood mononuclear cells; Pharmacokinetics; Therapeutic drug monitoring

Indexed keywords

CALCINEURIN INHIBITOR; CALCINEURIN PHOSPHATASE; CALMODULIN; CYCLOSPORIN; CYTOCHROME P450 3A5; EVEROLIMUS; IMMUNOSUPPRESSIVE AGENT; INOSINATE DEHYDROGENASE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHATASE; TACROLIMUS; UNCLASSIFIED DRUG;

ACUTE GRAFT REJECTION; AREA UNDER THE CURVE; ARTICLE; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG METABOLISM; DRUG MONITORING; ENZYME INHIBITION; ENZYME SUBSTRATE; HEART TRANSPLANTATION; HUMAN; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; LYMPHOCYTE; MAXIMUM PLASMA CONCENTRATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; UNSPECIFIED SIDE EFFECT;

IMMUNOSUPPRESSIVE DRUG; INTRACELLULAR; PERIPHERAL BLOOD MONONUCLEAR CELLS; PHARMACOKINETICS; THERAPEUTIC DRUG MONITORING;

CALCINEURIN; DRUG MONITORING; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LEUKOCYTES, MONONUCLEAR; TOR SERINE-THREONINE KINASES;

EID: 84884780217     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.06.003     Document Type: Review

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