Extreme prematurity and attention deficit: Epidemiology and prevention

Frontiers in Human Neuroscience

Volumn , Issue SEP, 2013, Pages

  Michael O'Shea, T ^a   Downey, L Corbin ^a   Kuban, Karl K C ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Attention; Attention deficit hyperactivity disorder; Extreme prematurity; Neurodevelopmental impairment; Neuroprotection

Indexed keywords

CORTICOSTEROID; ERYTHROPOIETIN; MAGNESIUM SULFATE; MELATONIN; PENTOXIFYLLINE;

ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN DAMAGE; CEREBRAL PALSY; CHILD BEHAVIOR CHECKLIST; CORTICOSTEROID THERAPY; DISEASE ASSOCIATION; ENCEPHALITIS; EXTREME PREMATURITY; HUMAN; INDUCED HYPOTHERMIA; INFANT; INTERVENTION STUDY; MATERNAL SMOKING; NECROTIZING ENTEROCOLITIS; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERINATAL CARE; POSTNATAL CARE; PREMATURITY; PRENATAL CARE; RISK FACTOR; RISK REDUCTION; VERY LOW BIRTH WEIGHT; WHITE MATTER LESION;

EID: 84884696477     PISSN: 16625161     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnhum.2013.00578     Document Type: Article

References (74)

1. Aarnoudse-Moens, C. S. H., Weisglas-Kuperus, N., van Goudoever, J. B., and Oosterlaan, J. (2009). Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weight children. Pediatrics 124, 717-728. doi: 10.1542/peds.2008-2816
2. Adler, N., Bush, N. R., and Pantell, M. S. (2012). Rigor, vigor, and the study of health disparities. Proc. Natl. Acad. Sci. U.S.A. 109, 17154-17159. doi: 10.1073/pnas.1121399109
3. Anderson, P. J., De Luca, C. R., Hutchinson, E., Spencer-Smith, M. M., Roberts, G., and Doyle, L. W. (2011). Attention problems in a representative sample of extremely preterm/extremely low birth weight children. Dev. Neuropsychol. 36, 57-73. doi: 10.1080/87565641.2011.540538
4. Bhutta, A. T., Cleves, M. A., Casey, P. H., Cradock, M. M., and Anand, K. J. S. (2002). Cognitive and behavioral outcomes of school-aged children who were born preterm-a meta-analysis. JAMA 288, 728-737. doi: 10.1001/jama.288.6.728
5. Bose, C. L., Laughon, M. M., Allred, E. N., O'Shea, T. M., Van Marter, L. J., Ehrenkranz, R. A., et al. (2013). Systemic inflammation associated with mechanical ventilation among extremely preterm infants. Cytokine 61, 315-322. doi: 10.1016/j.cyto.2012.10.014
6. Crowther, C. A., Doyle, L. W., Haslam, R. R., Hiller, J. E., Harding, J. E., and Robinson, J. S. (2007). Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. N. Engl. J. Med. 357, 1179-1189. doi: 10.1056/NEJMoa071152
7. Dalziel, S. R., Lim, V. K., Lambert, A., McCarthy, D., Parag, V., Rodgers, A., et al. (2005). Antenatal exposure to betamethasone: psychological functioning and health related quality of life 31 years after inclusion in randomised controlled trial. Br. Med. J. 331, 665-668A. doi: 10.1136/bmj.38576.494363.E0
8. Dammann, O., and O'Shea, T. M. (2008). Cytokines and perinatal brain damage. Clin. Perinatol. 35, 643-663. doi: 10.1016/j.clp.2008.07.011
9. Delobel-Ayoub, M., Arnaud, C., White-Koning, M., Casper, C., Pierrat, V., Garel, M., et al. (2009). Behavioral problems and cognitive performance at 5 years of age after very preterm birth: the EPIPAGE study. Pediatrics 123, 1485-1492. doi: 10.1542/peds.2008-1216
10. Dilek, M., Kumral, A., Okyay, E., Ozbal, S., Tugyan, K., Tuzun, F., et al. (2013). Protective effects of pen-toxifylline on lipopolysaccharide-induced white matter injury in a rat model of periventricular leukomalasia. J. Matern. Fetal. Neonatal. Med. doi: 10.3109/14767058.2013.798290. [Epub ahead of print].
11. Doyle, L. W., Crowther, C. A., Middleton, P., and Marret, S. (2009). Antenatal magnesium sul-fate and neurologic outcome in preterm infants. Obstet. Gynecol. 113, 1327-1333.
12. Elgen, I., Sommerfelt, K., and Markestad, T. (2002). Population based, controlled study of behavioural problems and psychiatric disorders in low birth-weight children at 11 years of age. Arch. Dis. Child. Fetal Neonatal Ed. 87, F128-F132. doi: 10.1136/fn.87.2.F128
13. Fleiss, B., and Gressens, P. (2012). Tertiary mechanisms of brain injury: a new hope for treatment of cerebral palsy. Lancet Neurol. 11, 556-566. doi: 10.1016/S1474-4422 (12)70058-3
14. Fukuda, H., Tomimatsu, T., Watanabe, N., Mu, J. W., Kohzuki, M., Endo, M., et al. (2001). Post-ischemic hypothermia blocks caspase-3 activation in the newborn rat brain after hypoxia-ischemia. Brain Res. 910, 187-191. doi: 10.1016/S0006-8993(01)02659-2
15. Gotsch, F., Romero, R., Kusanovic, J. P., Mazaki-Tovi, S., Pineles, B. L., Erez, O., et al. (2007). The fetal inflammatory response syndrome. Clin. Obstet. Gynecol. 50, 652-683. doi: 10.1097/GRF.0b013e3 1811ebef6
16. Gray, P. H., O'Callaghan, M. J., and Poulsen, L. (2008). Behaviour and quality of life at school age of children who had bronchopulmonary dysplasia. Early Hum. Dev. 84, 1-8. doi: 10.1016/j.earlhumdev. 2007.01.009
17. Hack, M., Taylor, H. G., Schluchter, M., Andreias, L., Drotar, D., and Klein, N. (2009). Behavioral outcomes of extremely low birth weight children at age 8 years. J. Dev. Behav. Pediatr. 30, 122-130. doi: 10.1097/DBP.0b013e318 19e6a16
18. Hagberg, H., Gressens, P., and Mallard, C. (2012). Inflammation during fetal and neonatal life: implications for neurologic and neu-ropsychiatric disease in children and adults. Ann. Neurol. 71, 444-457. doi: 10.1002/ ana.22620
19. Hagberg, H., Peebles, D., and Mallard, C. (2002). Models of white matter injury: comparison of infectious, hypoxic-ischemic, and excitotoxic insults. Ment. Retard. Dev. Disabil. Res. Rev. 8, 30-38. doi: 10.1002/mrdd.10007
20. Halliday, H. L., Ehrenkranz, R. A., and Doyle, L. W. (2009). Late (>7 days) postnatal corticos-teroids for chronic lung disease in preterm infants. Cochrane Database Syst. Rev. doi: 0.1002/14651858.CD001145.pub2
21. Halliday, H. L., Ehrenkranz, R. A., and Doyle, L. W. (2010). Early (<8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst. Rev. 1:CD001146. doi: 10.1002/14651858.CD001146.pub3
22. Hille, E. T. M., den Ouden, A. L., Saigal, S., Wolke, D., Lambert, M., Whitaker, A., et al. (2001). Behavioural problems in children who weigh 1000 g or less at birth in four countries. Lancet 357, 1641-1643. doi: 10.1016/S0140-6736(00)04818-2
23. Hinkle, S. N., Schieve, L. A., Stein, A. D., Swan, D. W., Ramakrishnan, U., and Sharma, A. J. (2012). Associations between maternal prepregnancy body mass index and child neurodevelopment at 2 years of age. Int. J. Obes. 36, 1312-1319. doi: 10.1038/ijo.2012.143
24. Hinkle, S. N., Sharma, A. J., Kim, S. Y., and Schieve, L. A. (2013). Maternal pre-pregnancy weight status and associations with children's development and disabilities at kindergarten. Int. J. Obes. (Lond). doi: 10.1038/ijo.2013.128. [Epub ahead of print].
25. Holzman, C., Lin, X. M., Senagore, P., and Chung, H. (2007). Histologic chorioamnionitis and preterm delivery. Am. J. Epidemiol. 166, 786-794. doi: 10.1093/aje/kwm168
26. Inder, T. E., Anderson, N. J., Spencer, C., Wells, S., and Volpe, J. J. (2003). White matter injury in the premature infant: a comparison between serial cranial sonographic and MR findings at term. Am. J. Neuroradiol. 24, 805-809.
27. Indredavik, M. S., Skranes, J. S., Vik, T., Heyerdahl, S., Romundstad, P., Myhr, G. E., et al. (2005). Low-birth-weight adolescents: psychiatric symptoms and cerebral MRI abnormalities. Pediatr. Neurol. 33, 259-266. doi: 10.1016/j.pediatrneurol.2005.05.002
28. Indredavik, M. S., Vik, T., Evensen, K. A. I., Skranes, J., Taraldsen, G., and Brubakk, A. M. (2010). Perinatal risk and psychiatric outcome in adolescents born preterm with very low birth weight or term small for gestational age. J. Dev. Behav. Pediatr. 31, 286-294. doi: 10.1097/DBP.0b013e3181d7b1d3
29. Jacobs, S. E., Berg, M., Hunt, R., Tarnow-Mordi, W. O., Inder, T. E., and Davis, P. G. (2013). Cooling for newborns with hypoxic ischaemic encephalopa-thy. Cochrane Database Syst. Rev. 1:CD003311. doi: 10.1002/14651858.CD003311.pub3
30. Johnson, S., Hollis, C., Kochhar, P., Hennessy, E., Wolke, D., and Marlow, N. (2010). Psychiatric disorders in extremely preterm children: longitudinal finding at age 11 years in the EPICure study. J. Am. Acad. Child Adolesc. Psychiatry 49, 453-463. doi: 10.1016/j.jaac. 2010.02.002
31. Johnson, S., and Marlow, N. (2011). Preterm birth and childhood psychiatric disorders. Pediatr. Res. 69, 11R-18R. doi: 10.1203/PDR.0b013e318212faa0
32. Kenyon, S., Pike, K., Jones, D. R., Brocklehurst, P., Marlow, N., Salt, A., et al. (2008a). Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up of the ORACLE I trial. Lancet 372, 1310-1318. doi: 10.1016/S0140-6736(08)61202-7
33. Kenyon, S., Pike, K., Jones, D. R., Brocklehurst, P., Marlow, N., Salt, A., et al. (2008b). Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the ORACLE II trial. Lancet 372, 1319-1327. doi: 10.1016/S0140-6736 (08)61203-9
34. Kumral, A., Baskin, H., Yesilirmak, D. C., Ergur, B. U., Aykan, S., Genc, S., et al. (2007). Erythropoietin attenuates lipopolysaccharide-induced white matter injury in the neonatal rat brain. Neonatology 92, 269-278. doi: 10.1159/000105493
35. Leibowitz, K. L., Moore, R. H., Ahima, R. S., Stunkard, A. J., Stallings, V. A., Berkowitz, R. I., et al. (2012). Maternal obesity associated with inflammation in their children. World J. Pediatr. 8, 76-79. doi: 10.1007/s12519-011-0292-6
36. Leviton, A., Hecht, J. L., Onderdonk, A. O., Kuban, K., O'Shea, T. M., Allred, E. N., et al. (2010). Microbiological and histologic characteristics of the extremely preterm infant's placenta predict white matter damage and later cerebral palsy. Pediatr. Res. 67, 95-101. doi: 10.1203/PDR.0b013e3181bf5fab
37. Leviton, A., O'Shea, T. M., Bednarek, F. J., Allred, E. N., Fichorova, R. N., and Dammann, O. (2012). Systemic responses of preterm new-borns with presumed or documented bacteraemia. Acta Paediatr. 101, 355-359. doi: 10.1111/j.1651-2227.2011.02527.x
38. Lindstrom, K., Lindblad, F., and Hjern, A. (2011). Preterm birth and attention-deficit/hyperactivity disorder in schoolchildren. Pediatrics 127, 858-865. doi: 10.1542/peds.2010-1279
39. Lorenz, J. M., Wooliever, D. E., Jetton, J. R., and Paneth, N. (1998). A quantitative review of mortality and developmental disability in extremely premature newborns. Arch. Pediatr. Adolesc. Med. 152, 425-435. doi: 10.1001/archpedi.152.5.425
40. Maalouf, E. F., Duggan, P. J., Counsell, S. J., Rutherford, M. A., Cowan, F., Azzopardi, D., et al. (2001). Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants. Pediatrics 107, 719-727. doi: 10.1542/peds.107.4.719
41. Martin, C. R., Bellomy, M., Allred, E. N., Fichorova, R. N., and Leviton, A. (2013). Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns. Fetal Pediatr. Pathol. 32, 222-234. doi: 10.3109/15513815.2012.721477
42. Martin, C. R., Dammann, O., Allred, E. N., Patel, S., O'Shea, T. M., Kuban, K. C. K., et al. (2010). Neurodevelopment of extremely preterm infants who had necrotizing enterocolitis with or without late bacteremia. J. Pediatr. 157, 751-756. doi: 10.1016/j.jpeds.2010.05.042
43. McElrath, T. F., Allred, E. N., Boggess, K. A., Kuban, K., O'Shea, T. M., Paneth, N., et al. (2009). Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational age. Am. J. Epidemiol. 170, 819-828. doi: 10.1093/aje/kwp206
44. McElrath, T. F., Fichorova, R. N., Allred, E. N., Hecht, J. L., Ismail, M., and Leviton, A. (2011). Blood protein profiles of infants differ by the pregnancy complication in infants born before the 28th week of gestation. Am. J. Obstet. Gynecol. 204, 418.e1-418.e12. doi: 10.1016/j.ajog. 2010.12.010
45. Miller, S. P., Cozzio, C. C., Goldstein, R. B., Ferriero, D. M., Partridge, J. C., Vigneron, D. B., et al. (2003). Comparing the diagnosis of white matter injury in premature new-borns with serial MR imaging and transfontanel ultrasonography findings. Am. J. Neuroradiol. 24, 1661-1669.
46. Mulder, H., Pitchford, N. J., Hagger, M. S., and Marlow, N. (2009). Development of executive function and attention in preterm children: a systematic review. Dev. Neuropsychol. 34, 393-421. doi: 10.1080/87565640902964524
47. Nadeau, L., Boivin, M., Tessier, R., Lefebvre, F., and Robaey, P. (2001). Mediators of behavioral problems in 7-year-old children born after 24 to 28 weeks of gestation. J. Dev. Behav. Pediatr. 22, 1-10. doi: 10.1097/00004703-200102000-00001
48. Nock, M. K., Kazdin, A. E., Hiripi, E., and Kessler, R. C. (2006). Prevalence, subtypes, and correlates of DSM-IV conduct disorder in the national comorbidity survey replication. Psychol. Med. 36, 699-710. doi: 10.1017/S0033291706007082
49. Nomura, Y., Marks, D. J., and Halperin, J. M. (2010). Prenatal exposure to maternal and paternal smoking on attention deficit hyper-activity disorders symptoms and diagnosis in offspring. J. Nerv. Ment. Dis. 198, 672-678. doi: 10.1097/NMD.0b013e3181ef3489
50. Paneth, N. S. (1995). The problem of low-birth-weight. Future of Child. 5, 19-34. doi: 10.2307/1602505
51. Peterson, J., Taylor, H. G., Minich, N., Klein, N., and Hack, M. (2006). Subnormal head circumference in very low birth weight children: neonatal correlates and school-age consequences. Early Hum. Dev. 82, 325-334. doi: 10.1016/j.earlhumdev.2005.09.014
52. Pineda, D. A., Palacio, L. G., Puerta, I. C., Merchan, V., Arango, C. P., Galvis, A. Y., et al. (2007). Environmental influences that affect attention deficit/hyperactivity disorder-study of a genetic isolate. Eur. Child Adolesc. Psychiatry 16, 337-346. doi: 10.1007/s00787-007-0605-4
53. Roberts, D., and Dalziel, S. (2006). Antenatal corti-costeroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst. Rev. 1:CD004454. doi: 10.1002/1465 1858.CD004454.pub2
54. Robertson, N. J., Faulkner, S., Fleiss, B., Bainbridge, A., Andorka, C., Price, D., et al. (2013). Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model. Brain 136, 90-105. doi: 10.1093/brain/aws285
55. Romero, R., Espinoza, J., Goncalves, L. F., Kusanovic, J. P., Friel, L., and Hassan, S. (2007). The role of inflammation and infection in preterm birth. Semin. Reprod. Med. 25, 21-39. doi: 10.1055/s-2006-956773
56. Rouse, D. (2007). A randomized controlled trial of magnesium sulfate for the prevention of cerebral palsy. Am. J. Obstet. Gynecol. 197, S2. doi: 10.1016/j.ajog.2007.10.002
57. Samara, M., Marlow, N., and Wolke, D. (2008). Pervasive behavior problems at 6 years of age in a total-population sample of children born at <= 25 weeks of gestation. Pediatrics 122, 562-573. doi: 10.1542/peds.2007-3231
58. Schmidt, B., Roberts, R. S., Davis, P., Doyle, L. W., Barrington, K. J., Ohlsson, A., et al. (2007). Long-term effects of caffeine therapy for apnea of prematurity. N. Engl. J Med. 357, 1893-1902. doi: 10.1056/NEJMoa 073679
59. Scott, M. N., Taylor, H. G., Fristad, M. A., Klein, N., Espy, K. A., Minich, N., et al. (2012). Behavior disorders in extremely preterm/extremely low birth weight children in kindergarten. J.Dev. Behav. Pediatr. 33, 202-213. doi: 10.1097/DBP.0b013e3182475287
60. Serenius, F., Kallen, K., Blennow, M., Ewald, U., Fellman, V., Holmstrom, G., et al. (2013). Neurodevelopmental outcome in extremely preterm infants at 2.5 years after active perinatal care in Sweden. JAMA 309, 1810-1820. doi: 10.1001/jama. 2013.3786
61. Sisk, P. M., Lovelady, C. A., Dillard, R. G., Gruber, K. J., and O'Shea, T. M. (2007). Early human milk feeding is associated with a lower risk of necrotizing enterocolitis in very low birth weight infants. J. Perinatol. 27, 428-433. doi: 10.1038/sj.jp.7211758
62. Skranes, J., Vangberg, T. R., Kulseng, S., Indredavik, M. S., Evensen, K. A. I., Martinussen, M., et al. (2007). Clinical findings and white matter abnormalities seen on diffusion tensor imaging in adolescents with very low birth weight. Brain 130, 654-666. doi: 10.1093/brain/ awm001
63. Tanaka, K., Hosozawa, M., Kudo, N., Yoshikawa, N., Hisata, K., Shoji, H., et al. (2013). The pilot study: sphingomyelin-fortified milk has a positive association with the neurobehavioural development of very low birth weight infants during infancy, randomized control trial. Brain Dev. 35, 45-52. doi: 10.1016/j.braindev. 2012.03.004
64. Thapar, A., Cooper, M., Jefferies, R., and Stergiakouli, E. (2012). What causes attention deficit hyperac-tivity disorder. Arch. Dis. Child. 97, 260-265. doi: 10.1136/archdischild-2011-300482
65. Thornton, C., Rousset, C. I., Kichev, A., Miyakuni, Y., Vontell, R., Baburamani, A. A., et al. (2012). Molecular mechanisms of neonatal brain injury. Neurol. Res. Int. 2012, 16. doi: 10.1155/2012/506320
66. Tomimatsu, T., Fukuda, H., Endo, M., Watanabe, N., Mu, J. W., Kohzuki, M., et al. (2001). Effects of hypothermia on neonatal hypoxic-ischemic brain injury in the rat: phosphorylation of Akt, activation of caspase-3-like protease. Neurosci. Lett. 312, 21-24. doi: 10.1016/S0304-3940(01)02178-4
67. Tomimatsu, T., Fukuda, H., Endoh, M., Mu, J., Kanagawa, T., Hosono, T., et al. (2003). Long-Term neuroprotective effects of hypothermia on neonatal hypoxic-ischemic brain injury in rats, assessed by auditory brainstem response. Pediatr. Res. 53, 57-61. doi: 10.1203/00006450-200301000-00012
68. Vuillermot, S., Joodmardi, E., Perlmann, T., Ogren, S. O., Feldon, J., and Meyer, U. (2012). Prenatal immune activation interacts with genetic nurr1 deficiency in the development of attentional impairments. J. Neurosci. 32, 436-451. doi: 10.1523/JNEUROSCI.4831-11.2012
69. Wang, X. Y., Hellgren, G., Lofqvist, C., Li, W. L., Hellstrom, A., Hagberg, H., et al. (2009). White Matter Damage After Chronic Subclinical Inflammation in Newborn Mice. J. Child Neurol. 24, 1171-1178. doi: 10.1177/0883073809338068
70. Wang, X. Y., Rousset, C. I., Hagberg, H., and Mallard, C. (2006). Lipopolysaccharide-induced inflammation and perinatal brain injury. Semin. Fetal Neonatal Med. 11, 343-353. doi: 10.1016/j.siny.2006.04.002
71. Weijer-Bergsma, E. V., Wijnroks, L., and Jongmans, M. J. (2008). Attention development in infants and preschool children born preterm: a review. Infant Behav. Dev. 31, 333-351. doi: 10.1016/j.infbeh.2007.12.003
72. Whitaker, A. H., Van Rossem, R., Feldman, J. F., Schonfeld, I. S., Pinto-Martin, J. A., Tore, C., et al. (1997). Psychiatric outcomes in low-birth-weight children at age 6 years: relation to neonatal cranial ultrasound abnormalities. Arch. Gen. Psychiatry 54, 847-856. doi: 10.1001/archpsyc.1997.01830210091012
73. Wood, N. S., Costeloe, K., Gibson, A. T., Hennessy, E. M., Marlow, N., and Wilkinson, A. R. (2005). The EPICure study: associations and antecedents of neurological and developmental disability at 30 months of age following extremely preterm birth. Arch. Dis. Child. Fetal Neonatal Ed. 90, 134-140. doi: 10.1136/adc.2004. 052407
74. Yeh, T. F., Lin, Y. J., Lin, H. C., Huang, C. C., Hsieh, W. S., Lin, C. H., et al. (2004). Outcomes at school age after postnatal dexamethasone therapy for lung disease of prematurity. N. Engl. J. Med. 350, 1304-1313. doi: 10.1056/NEJMoa032089