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Volumn 69, Issue , 2013, Pages 554-563

The antitumor activity of zinc(II) and copper(II) complexes with 5,7-dihalo-substituted-8-quinolinoline

(8) Liu, Yan Cheng a Wei, Jian Hua a Chen, Zhen Feng a Liu, Mei a Gu, Yun Qiong a Huang, Ke Bin a Li, Zhu Quan a Liang, Hong a

a Normal University (China)

Author keywords

5,7 Dihalo substituted 8 quinolinoline; Crystal structure; Cu(II) complex; Cytotoxicity; DNA binding; Zn(II) complex

Indexed keywords

8 QUINOLINOL DERIVATIVE; ANTINEOPLASTIC AGENT; COPPER COMPLEX; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; ZINC COMPLEX;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INTERCALATION COMPLEX; TUMOR CELL; WESTERN BLOTTING;

5,7-DIHALO-SUBSTITUTED-8-QUINOLINOLINE; CRYSTAL STRUCTURE; CU(II) COMPLEX; CYTOTOXICITY; DNA BINDING; ZN(II) COMPLEX;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COPPER; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84884695960 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2013.08.033 Document Type: Article

Times cited : (104)

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