Arterial 18F-Fluorodeoxyglucose uptake reflects balloon catheter-induced thrombus formation and tissue factor expression via nuclear factor-κB in rabbit atherosclerotic lesions

Circulation Journal

Volumn 77, Issue 10, 2013, Pages 2626-2635

  Yamashita, Atsushi ^a   Zhao, Yan ^b   Zhao, Songji ^b   Matsuura, Yunosuke ^a   Sugita, Chihiro ^a   Iwakiri, Takashi ^a   Okuyama, Nozomi ^a   Ohe, Kazuyo ^c   Koshimoto, Chihiro ^a   Kawai, Keiichi ^c,d   Tamaki, Nagara ^b   Kuge, Yuji ^b   Asada, Yujiro ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d UNIVERSITY OF FUKUI   (Japan)

Author keywords

18F FDG; Atherothrombosis; Nuclear factor B; Rabbits; Tissue factor

Indexed keywords

CD163 ANTIGEN; FIBRIN; FIBRINOGEN RECEPTOR; FLUORODEOXYGLUCOSE F 18; HEPARIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; THROMBOPLASTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTORADIOGRAPHY; BALLOON CATHETER; CONTROLLED STUDY; CORRELATION ANALYSIS; HISTOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; RABBIT; RADIOACTIVITY; THROMBOGENICITY;

ANIMALS; ATHEROSCLEROSIS; CATHETERS; FLUORODEOXYGLUCOSE F18; GENE EXPRESSION REGULATION; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; NF-KAPPA B; PLAQUE, ATHEROSCLEROTIC; POSITRON-EMISSION TOMOGRAPHY; RABBITS; RADIOPHARMACEUTICALS; THROMBOPLASTIN; THROMBOSIS;

EID: 84884668337     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-12-1463     Document Type: Article

References (38)

1. Sato Y, Hatakeyama K, Marutsuka K, Asada Y. Incidence of asymptomatic coronary thrombosis and plaque disruption: Comparison of non-cardiac and cardiac deaths among autopsy cases. Thromb Res 2009; 124: 19-23.
2. Ueda Y, Ogasawara N, Matsuo K, Hirotani S, Kashiwase K, Hirata A, et al. Acute coronary syndrome: Insight from angioscopy. Circ J 2010; 74: 411-417.
3. Lee KW, Lip GY. Acute coronary syndromes: Virchow's triad revisited. Blood Coagul Fibrinol 2003; 14: 605-625.
4. Drake TA, Morrissey JH, Edgington TS. Selective cellular expression of tissue factor in human tissues: Implications for disorders of hemostasis and thrombosis. Am J Pathol 1989; 134: 1087-1097.
5. Hatakeyama K, Asada Y, Marutsuka K, Sato Y, Kamikubo Y, Sumiyoshi A. Localization and activity of tissue factor in human aortic atherosclerotic lesions. Atherosclerosis 1997; 133: 213-219.
6. Nicholls SJ, Andrews J, Puri R, Uno K, Kataoka Y. Imaging progression of coronary atherosclerosis. Circ J 2012; 77: 3-10.
7. Zagorchev L, Mulligan-Kehoe MJ. Advances in imaging angiogen-esis and inflammation in atherosclerosis. Thromb Haemost 2011; 105: 820-827.
8. Zhao Y, Zhao S, Kuge Y, Strauss WH, Blankenberg FG, Tamaki N. Localization of deoxyglucose and annexin A5 in experimental ath-eroma correlates with macrophage infiltration but not lipid deposition in the lesion. Mol Imaging Biol 2011; 13: 712-720.
9. 18F-FDG accumulation in atherosclerotic plaques: Immunohistochem-ical and PET imaging study. J Nucl Med 2004; 45: 1245-1250.
10. Tawakol A, Migrino RQ, Hoffmann U, Abbara S, Houser S, Gewirtz H, et al. Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography. J Nucl Cardiol 2005; 12: 294-301.
11. 18F]-fluorodeoxyglu-cose positron emission tomography is associated with the metabolic syndrome. J Am Coll Cardiol 2007; 49: 1533-1539.
12. 18F-FDG PET/CT identifes patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease. J Nucl Med 2009; 50: 1611-1620.
13. Grandpierre S, Desandes E, Meneroux B, Djaballah W, Mandry D, Netter F, et al. Arterial foci of F-18 fluorodeoxyglucose are associated with an enhanced risk of subsequent ischemic stroke in cancer patients: A case-control pilot study. Clin Nucl Med 2011; 36: 85-90.
14. Aziz K, Berger K, Claycombe K, Huang R, Patel R, Abela GS. Non-invasive detection and localization of vulnerable plaque and arterial thrombosis with computed tomography angiography/positron emission tomography. Circulation 2008; 117: 2061-2070.
15. Yamashita A, Matsuda S, Matsumoto T, Moriguchi-Goto S, Takahashi M, Sugita C, et al. Thrombin generation by intimal tissue factor contributes to thrombus formation on macrophage-rich neointima but not normal intima of hyperlipidemic rabbits. Atherosclerosis 2009; 206: 418-426.
16. Zhao S, Kuge Y, Yi M, Zhao Y, Hatano T, Magota K, et al. Dynamic 11C-methionine PET analysis has an additional value for differentiating malignant tumors from granulomas: An experimental study using small animal PET. Eur J Nucl Med Mol Imaging 2011; 38: 1876-1886.
17. Aide N, Louis MH, Dutoit S, Labiche A, Lemoisson E, Briand M, et al. Improvement of semi-quantitative small-animal PET data with recovery coefficients: A phantom and rat study. Nucl Med Commun 2007; 28: 813-822.
18. Kaim AH, Weber B, Kurrer MO, Gottschalk J, Von Schulthess GK, Buck A. Autoradiographic quantification of 18F-FDG uptake in experimental soft-tissue abscesses in rats. Radiology 2002; 223: 446-451.
19. Neumann RA, Knobler RM, Pieczkowski F, Gebhart W. Enzyme histochemical analysis of cell viability after argon laser-induced coagulation necrosis of the skin. J Am Acad Dermatol 1991; 25: 991-998.
20. Rogers IS, Nasir K, Figueroa AL, Cury RC, Hoffmann U, Vermylen DA, et al. Feasibility of FDG imaging of the coronary arteries: Comparison between acute coronary syndrome and stable angina. JACC Cardiovasc Imaging 2010; 3: 388-397.
21. Patel R, Janoudi A, Vedre A, Aziz K, Tamhane U, Rubinstein J, et al. Plaque rupture and thrombosis are reduced by lowering cholesterol levels and crystallization with ezetimibe and are correlated with fuo-rodeoxyglucose positron emission tomography. Arterioscler Thromb Vasc Biol 2011; 31: 2007-2014.
22. Crawley JT, Zanardelli S, Chion CK, Lane DA. The central role of thrombin in hemostasis. J Thromb Haemost 2007; 5(Suppl 1): 95-101.
23. Davies JR, Izquierdo-Garcia D, Rudd JH, Figg N, Richards HK, Bird JL, et al. FDG-PET can distinguish inflamed from non-inflamed plaque in an animal model of atherosclerosis. Int J Cardiovasc Imaging 2010; 26: 41-48.
24. 18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung. Neoplasia 2005; 7: 369-379.
25. 18F]fuorodeoxyglucose in human monocyte-macrophages in vitro. Eur J Nucl Med Mol Imaging 2003; 30: 267-273.
26. Myers KS, Rudd JH, Hailman EP, Bolognese JA, Burke J, Pinto CA, et al. Correlation between arterial FDG uptake and biomarkers in peripheral artery disease. JACC Cardiovasc Imaging 2012; 5: 38-45.
27. Waldo SW, Li Y, Buono C, Zhao B, Billings EM, Chang J, et al. Heterogeneity of human macrophages in culture and in atherosclerotic plaques. Am J Pathol 2008; 172: 1112-1126.
28. Boyle JJ, Harrington HA, Piper E, Elderfeld K, Stark J, Landis RC, et al. Coronary intraplaque hemorrhage evokes a novel atheroprotec-tive macrophage phenotype. Am J Pathol 2009; 174: 1097-1108.
29. Tawakol A, Rudd JH, Fayad ZA, Boscá L. Classical but not innate activation augments 2-deoxy-D-glucose uptake in macrophages: Implications for atherosclerosis imaging. J Nucl Med 2012; 53(Suppl 1): 141.
30. Monaco C, Paleolog E. Nuclear factor kappaB: A potential therapeu-tic target in atherosclerosis and thrombosis. Cardiovasc Res 2004; 61: 671-682.
31. Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R, et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest 1996; 97: 1715-1722.
32. Hajra L, Evans AI, Chen M, Hyduk SJ, Collins T, Cybulsky MI. The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc Natl Acad Sci USA 2000; 97: 9052-9057.
33. Chen H, Yang J, Zhang Q, Chen LH, Wang Q. Corosolic acid ameliorates atherosclerosis in apolipoprotein E-deficient mice by regulating the nuclear factor-κB signaling pathway and inhibiting monocyte chemoattractant protein-1 expression. Circ J 2012; 76: 995-1003.
34. Wilson SH, Best PJ, Edwards WD, Holmes DR Jr, Carlson PJ, Celermajer DS, et al. Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris. Atherosclerosis 2002; 160: 147-153.
35. Hatakeyama K, Asada Y, Marutsuka K, Kataoka H, Sato Y, Sumiyoshi A. Expression of tissue factor in the rabbit aorta after balloon injury. Atherosclerosis 1998; 139: 265-271.
36. Mackman N. Regulation of the tissue factor gene. Thromb Haemost 1997; 78: 747-754.
37. Paulmier B, Duet M, Khayat R, Pierquet-Ghazzar N, Laissy JP, Maunoury C, et al. Arterial wall uptake of fluorodeoxyglucose on PET imaging in stable cancer disease patients indicates higher risk for cardiovascular events. J Nucl Cardiol 2008; 15: 209-217.
38. Folco EJ, Sheikine Y, Rocha VZ, Christen T, Shvartz E, Sukhova GK, et al. Hypoxia but not inflammation augments glucose uptake in human macrophages: Implications for imaging atherosclerosis with 18fuorine-labeled 2-deoxy-D-glucose positron emission tomography. J Am Coll Cardiol 2011; 58: 603-614.