A rapid membrane potential assay to monitor CFTR function and inhibition

Journal of Biomolecular Screening

Volumn 18, Issue 9, 2013, Pages 1132-1137

  Maitra, Rangan ^a   Sivashanmugam, Perumal ^b   Warner, Keith ^a  

^a RTI INTERNATIONAL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

assay; CFTR; cystic fibrosis; ion channel; membrane potential

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FORMOTEROL FUMARATE; GLYCOPYRRONIUM BROMIDE; NITRENDIPINE; SERTRALINE;

ARTICLE; CELL STRAIN HEK293; EMBRYO; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION;

ASSAY; CFTR; CYSTIC FIBROSIS; ION CHANNEL; MEMBRANE POTENTIAL;

BIOLOGICAL ASSAY; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FLUORESCENT DYES; HEK293 CELLS; HUMANS; ION TRANSPORT; LIGANDS; MEMBRANE POTENTIALS; MUTATION; SIGNAL-TO-NOISE RATIO; SMALL MOLECULE LIBRARIES; SPECTROMETRY, FLUORESCENCE; TIME FACTORS;

EID: 84884666084     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113488420     Document Type: Article

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