메뉴 건너뛰기




Volumn 382, Issue 1-2, 2013, Pages 83-92

Ganglioside GM3 promotes HGF-stimulated motility of murine hepatoma cell through enhanced phosphorylation of cMet at specific tyrosine sites and PI3K/Akt-mediated migration signaling

Author keywords

cMet; GM3; Metastasis; PI3K

Indexed keywords

BETA ACTIN; GANGLIOSIDE GM3; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; TYROSINE;

EID: 84884660475     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1720-9     Document Type: Article
Times cited : (22)

References (26)
  • 1
    • 0027467490 scopus 로고
    • Ganglioside metabolism. Enzymology, topology, and regulation
    • 8449895
    • Van Echten G, Sandhoff K (1993) Ganglioside metabolism. Enzymology, topology, and regulation. J Biol Chem 268:5341-5344
    • (1993) J Biol Chem , vol.268 , pp. 5341-5344
    • Van Echten, G.1    Sandhoff, K.2
  • 2
    • 0038532523 scopus 로고    scopus 로고
    • Role of tumor-associated gangliosides in cancer progression
    • 12770784 10.1016/S0300-9084(03)00006-3 1:CAS:528:DC%2BD3sXjvV2msL8%3D
    • Birkle S, Zeng G, Gao L, Yu RK, Aubry J (2003) Role of tumor-associated gangliosides in cancer progression. Biochimie 85:455-463
    • (2003) Biochimie , vol.85 , pp. 455-463
    • Birkle, S.1    Zeng, G.2    Gao, L.3    Yu, R.K.4    Aubry, J.5
  • 3
    • 0030480250 scopus 로고    scopus 로고
    • Tumor malignancy defined by aberrant glycosylation and sphingo(glyco) lipid metabolism
    • 8968075 1:CAS:528:DyaK28Xntl2mtr4%3D
    • Hakomori S (1996) Tumor malignancy defined by aberrant glycosylation and sphingo(glyco) lipid metabolism. Cancer Res 56:5309-5318
    • (1996) Cancer Res , vol.56 , pp. 5309-5318
    • Hakomori, S.1
  • 4
    • 0032502722 scopus 로고    scopus 로고
    • GM3-enriched microdomain involved in cell adhesion and signal transduction through carbohydrate-carbohydrate interaction in mouse melanoma B16 cells
    • 9535903 10.1074/jbc.273.15.9130 1:CAS:528:DyaK1cXis1eku70%3D
    • Iwabuchi K, Yamamura S, Prinetti A, Handa K, Hakomori S (1998) GM3-enriched microdomain involved in cell adhesion and signal transduction through carbohydrate-carbohydrate interaction in mouse melanoma B16 cells. J Biol Chem 273:9130-9138
    • (1998) J Biol Chem , vol.273 , pp. 9130-9138
    • Iwabuchi, K.1    Yamamura, S.2    Prinetti, A.3    Handa, K.4    Hakomori, S.5
  • 5
    • 0023025941 scopus 로고
    • Ganglioside-mediated modulation of cell growth: Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor
    • 2418024 1:CAS:528:DyaL28XhtVeitb0%3D
    • Bremer EG, Schlessinger J, Hakomori S (1986) Ganglioside-mediated modulation of cell growth: specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor. J Biol Chem 261:2434-2440
    • (1986) J Biol Chem , vol.261 , pp. 2434-2440
    • Bremer, E.G.1    Schlessinger, J.2    Hakomori, S.3
  • 6
    • 0023761154 scopus 로고
    • Ganglioside-mediated modulation of cell growth: Specific effects of GM3 and lyso-GM3 in tyrosine phosphorylation of the epidermal growth factor receptor
    • 2839511 1:CAS:528:DyaL1cXlsVehurs%3D
    • Hanai N, Nores GA, MacLeod C, Torres-Mendez CR, Hakomori S (1988) Ganglioside-mediated modulation of cell growth: specific effects of GM3 and lyso-GM3 in tyrosine phosphorylation of the epidermal growth factor receptor. J Biol Chem 263:10915-10921
    • (1988) J Biol Chem , vol.263 , pp. 10915-10921
    • Hanai, N.1    Nores, G.A.2    Macleod, C.3    Torres-Mendez, C.R.4    Hakomori, S.5
  • 7
    • 0029743653 scopus 로고    scopus 로고
    • Ganglioside GM3 inhibition of EGF receptor mediated signal transduction
    • 8842703 10.1093/glycob/6.4.399 1:CAS:528:DyaK28XkslOgtb0%3D
    • Rebbaa A, Hurh J, Yamamoto K, Kersey D, Bremer EG (1996) Ganglioside GM3 inhibition of EGF receptor mediated signal transduction. Glycobiology 6:399-406
    • (1996) Glycobiology , vol.6 , pp. 399-406
    • Rebbaa, A.1    Hurh, J.2    Yamamoto, K.3    Kersey, D.4    Bremer, E.G.5
  • 8
    • 0020336447 scopus 로고
    • GM3 ganglioside induces hamster fibroblast growth factor inhibition in chemically defined medium: Ganglioside may regulate growth factor receptor function
    • 6288031 10.1016/0006-291X(82)91769-7 1:CAS:528:DyaL38XksFWjsrc%3D
    • Bremer EG, Hakomori SI (1982) GM3 ganglioside induces hamster fibroblast growth factor inhibition in chemically defined medium: ganglioside may regulate growth factor receptor function. Biochem Biophys Res Commun 106:711-728
    • (1982) Biochem Biophys Res Commun , vol.106 , pp. 711-728
    • Bremer, E.G.1    Hakomori, S.I.2
  • 9
    • 0030198386 scopus 로고    scopus 로고
    • Differential modulation of basic fibroblast and epidermal growth factor receptor activation by ganglioside GM3 in cultured retinal Muller glia
    • 8840162 10.1002/(SICI)1098-1136(199607)17:3<206: AID-GLIA3>3.0. CO;2-Z 1:STN:280:DyaK28vjslCrtA%3D%3D
    • Meuillet E, Cremel G, Dreyfus H, Hicks D (1996) Differential modulation of basic fibroblast and epidermal growth factor receptor activation by ganglioside GM3 in cultured retinal Muller glia. Glia 17:206-216
    • (1996) Glia , vol.17 , pp. 206-216
    • Meuillet, E.1    Cremel, G.2    Dreyfus, H.3    Hicks, D.4
  • 10
    • 0027325432 scopus 로고
    • Mechanism through which gangliosides inhibit PDGF-stimulated mitogenesis in intact Swiss 3T3 cells: Receptor tyrosine phosphorylation, intracellular calcium, and receptor binding
    • 8416794 10.1006/excr.1993.1006 1:CAS:528:DyaK3sXnsVehuw%3D%3D
    • Yates AJ, Brocklin JV, Saqr HE, Guan Z, Stokes BT (1993) Mechanism through which gangliosides inhibit PDGF-stimulated mitogenesis in intact Swiss 3T3 cells: receptor tyrosine phosphorylation, intracellular calcium, and receptor binding. Exp Cell Res 204:38-45
    • (1993) Exp Cell Res , vol.204 , pp. 38-45
    • Yates, A.J.1    Brocklin, J.V.2    Saqr, H.E.3    Guan, Z.4    Stokes, B.T.5
  • 11
    • 0029073704 scopus 로고
    • Ganglioside modulation of PDGF receptor. A model for ganglioside functions
    • 8523078 10.1007/BF01052661 1:STN:280:DyaK287jtFSqtQ%3D%3D
    • Yates AJ, Saqr HE, Van Brocklyn J (1995) Ganglioside modulation of PDGF receptor. A model for ganglioside functions. J Neurooncol 24:65-73
    • (1995) J Neurooncol , vol.24 , pp. 65-73
    • Yates, A.J.1    Saqr, H.E.2    Van Brocklyn, J.3
  • 12
    • 0027156466 scopus 로고
    • Gangliosides inhibit platelet-derived growth factor-stimulated receptor dimerization in human glioma U1242MG and Swiss 3T3 cells
    • 8515285 10.1111/j.1471-4159.1993.tb03581.x
    • Van Brocklyn JE, Bremer EG, Yates AJ (1993) Gangliosides inhibit platelet-derived growth factor-stimulated receptor dimerization in human glioma U1242MG and Swiss 3T3 cells. J Neurochem 61:371-374
    • (1993) J Neurochem , vol.61 , pp. 371-374
    • Van Brocklyn, J.E.1    Bremer, E.G.2    Yates, A.J.3
  • 13
    • 50049110689 scopus 로고    scopus 로고
    • Ganglioside GM3 suppresses the pro-angiogenic effects of vascular endothelial growth factor and ganglioside GD1A
    • 18287616 10.1194/jlr.R800006-JLR200 1:CAS:528:DC%2BD1cXltFSltrg%3D
    • Mukherjee P, Faber AC, Shelton LM, Baek RC, Chiles TC (2008) Ganglioside GM3 suppresses the pro-angiogenic effects of vascular endothelial growth factor and ganglioside GD1A. J Lipid Res 49:929-938
    • (2008) J Lipid Res , vol.49 , pp. 929-938
    • Mukherjee, P.1    Faber, A.C.2    Shelton, L.M.3    Baek, R.C.4    Chiles, T.C.5
  • 14
    • 58949099403 scopus 로고    scopus 로고
    • Ganglioside GM3 inhibits VEGF/VEGFR-2-mediated angiogenesis: Direct interaction of GM3 with VEGFR-2
    • 18974200 10.1093/glycob/cwn114 1:CAS:528:DC%2BD1MXhtVegu7k%3D
    • Chung TW, Kim SJ, Choi HJ, Kim KJ (2009) Ganglioside GM3 inhibits VEGF/VEGFR-2-mediated angiogenesis: direct interaction of GM3 with VEGFR-2. Glycobiology 19(3):229-239
    • (2009) Glycobiology , vol.19 , Issue.3 , pp. 229-239
    • Chung, T.W.1    Kim, S.J.2    Choi, H.J.3    Kim, K.J.4
  • 15
    • 0008222162 scopus 로고
    • Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement
    • Gherardi E, Gray J, Stoker M, Perryman M, Furlong R (1989) Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc Natl Acad Sci USA 86:5844-5848
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5844-5848
    • Gherardi, E.1    Gray, J.2    Stoker, M.3    Perryman, M.4    Furlong, R.5
  • 16
    • 0000975548 scopus 로고
    • Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures
    • Nakamura T, Teramoto H, Ichihara A (1986) Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures. Proc Natl Acad Sci USA 83:6489-6493
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6489-6493
    • Nakamura, T.1    Teramoto, H.2    Ichihara, A.3
  • 17
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • 2952888 10.1038/327239a0 1:STN:280:DyaL2s3gtF2ltA%3D%3D
    • Stoker M, Gherardi E, Perryman M, Gray J (1987) Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327:239-242
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 18
    • 0028268338 scopus 로고
    • Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity
    • 8134112 1:CAS:528:DyaK2cXis1Ojtr8%3D
    • Bellusci S, Moens G, Gaudino G, Comoglio P, Nakamura T (1994) Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. Oncogene 9:1091-1099
    • (1994) Oncogene , vol.9 , pp. 1091-1099
    • Bellusci, S.1    Moens, G.2    Gaudino, G.3    Comoglio, P.4    Nakamura, T.5
  • 19
    • 0026655776 scopus 로고
    • Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor
    • 1406687 1:CAS:528:DyaK3sXitVWhtA%3D%3D
    • Rong S, Bodescot M, Blair D, Dunn J, Nakamura T (1992) Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol 12:5152-5158
    • (1992) Mol Cell Biol , vol.12 , pp. 5152-5158
    • Rong, S.1    Bodescot, M.2    Blair, D.3    Dunn, J.4    Nakamura, T.5
  • 20
    • 44849100284 scopus 로고    scopus 로고
    • Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells
    • 10.1186/bcr1841
    • Gu Y, Zhang J, Mi W, Yang J, Han F, Lu X, Yu W (2008) Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells. Breast Cancer Res 10(1):1-12
    • (2008) Breast Cancer Res , vol.10 , Issue.1 , pp. 1-12
    • Gu, Y.1    Zhang, J.2    Mi, W.3    Yang, J.4    Han, F.5    Lu, X.6    Yu, W.7
  • 21
    • 41149147556 scopus 로고    scopus 로고
    • Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway
    • 10.1073/pnas.0709619104
    • Todeschini AR, Dos Santos JN, Handa K, Hakomori SI (2008) Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway. Proc Natl Acad Sci USA 105(6):925-930
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.6 , pp. 925-930
    • Todeschini, A.R.1    Dos Santos, J.N.2    Handa, K.3    Hakomori, S.I.4
  • 22
    • 0021954882 scopus 로고
    • A solvent partition method purification
    • 3993932 10.1016/0003-2697(85)90419-1 1:CAS:528:DyaL2MXktVeit7s%3D
    • Ladisch S, Gillard B (1985) A solvent partition method purification. Anal Biochem 146:220-231
    • (1985) Anal Biochem , vol.146 , pp. 220-231
    • Ladisch, S.1    Gillard, B.2
  • 23
    • 0037180329 scopus 로고    scopus 로고
    • Regulation of growth factor receptors by gangliosides
    • Miljan EA, Bremer EG (2002) Regulation of growth factor receptors by gangliosides. Sci STKE 2002(160):re15
    • (2002) Sci STKE , vol.2002 , Issue.160 , pp. 15
    • Miljan, E.A.1    Bremer, E.G.2
  • 24
    • 64849102583 scopus 로고    scopus 로고
    • Role of c-Met in cancer: Emphasis on lung cancer
    • 10.1053/j.seminoncol.2009.02.008
    • Salgia R (2009) Role of c-Met in cancer: emphasis on lung cancer. Semin Oncol 36:52-58
    • (2009) Semin Oncol , vol.36 , pp. 52-58
    • Salgia, R.1
  • 25
    • 0027292358 scopus 로고
    • Tyrosine phosphorylation of phospholipase C gamma in c-met/HGF receptor-stimulated hepatocytes: Comparison with HepG2 hepatocarcinoma cells
    • 7679901 10.1006/bbrc.1993.1125 1:CAS:528:DyaK3sXitVGqtLo%3D
    • Okano Y, Mizuno K, Osada S, Nakamura T, Nozawa Y (1993) Tyrosine phosphorylation of phospholipase C gamma in c-met/HGF receptor-stimulated hepatocytes: comparison with HepG2 hepatocarcinoma cells. Biochem Biophys Res Commun 190:842-848
    • (1993) Biochem Biophys Res Commun , vol.190 , pp. 842-848
    • Okano, Y.1    Mizuno, K.2    Osada, S.3    Nakamura, T.4    Nozawa, Y.5
  • 26
    • 0034613202 scopus 로고    scopus 로고
    • Hepatocyte growth factor-induced differential activation of phospholipase cgamma 1 and phosphatidylinositol 3-kinase is regulated by tyrosine phosphatase SHP-1 in astrocytes
    • 10896658 10.1074/jbc.M002817200 1:CAS:528:DC%2BD3cXntlCit7o%3D
    • Machide M, Kamitori K, Kohsaka S (2000) Hepatocyte growth factor-induced differential activation of phospholipase cgamma 1 and phosphatidylinositol 3-kinase is regulated by tyrosine phosphatase SHP-1 in astrocytes. J Biol Chem 275(40):31392-31398
    • (2000) J Biol Chem , vol.275 , Issue.40 , pp. 31392-31398
    • Machide, M.1    Kamitori, K.2    Kohsaka, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.