메뉴 건너뛰기




Volumn 9, Issue 9, 2013, Pages 1962-1970

Intranasal vaccination with an inactivated whole influenza virus vaccine induces strong antibody responses in serum and nasal mucus of healthy adults

Author keywords

Haemagglutination inhibiting antibody; Healthy adult volunteer; Influenza virus; Intranasal vaccination; Neutralizing antibody

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INFLUENZA VACCINE; NEUTRALIZING ANTIBODY;

EID: 84884612155     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/hv.25458     Document Type: Article
Times cited : (64)

References (50)
  • 1
    • 0001387044 scopus 로고    scopus 로고
    • Orthomyxoviruses
    • In: Fields BN, Knipe DM, M. HP, Chanock RM, Melnick JL, Monath TP, et al., eds. Philadelphia: Lippincott Williams & Wilkins
    • Murphy BR, Webster RG. Orthomyxoviruses. In: Fields BN, Knipe DM, M. HP, Chanock RM, Melnick JL, Monath TP, et al., eds. Fields Virology. Philadelphia: Lippincott Williams & Wilkins, 1996:1397-445.
    • (1996) Fields Virology , pp. 1397-1445
    • Murphy, B.R.1    Webster, R.G.2
  • 2
    • 0024529561 scopus 로고
    • The systemic and mucosal immune response of humans to influenza a virus
    • PMID:2659262
    • Murphy BR, Clements ML. The systemic and mucosal immune response of humans to influenza A virus. Curr Top Microbiol Immunol 1989; 146:107-16; PMID:2659262; http://dx.doi.org/10.1007/978-3-642-74529-4-12
    • (1989) Curr Top Microbiol Immunol , vol.14 , pp. 6107-6116
    • Murphy, B.R.1    Clements, M.L.2
  • 3
    • 0002808340 scopus 로고
    • Mucosal immunity to viruses
    • In: Ogra PL, Mestecky J, Lamm ME, Strober W, McGee JR, Bienenstock J, eds. San Diego: Academic Press
    • Murphy BR. Mucosal Immunity to Viruses. In: Ogra PL, Mestecky J, Lamm ME, Strober W, McGee JR, Bienenstock J, eds. Handbook of Mucosal Immunology. San Diego: Academic Press, 1994:333-43.
    • (1994) Handbook of Mucosal Immunology , pp. 333-343
    • Murphy, B.R.1
  • 4
    • 0025155641 scopus 로고
    • Functional role of respiratory tract haemagglutinin-specific iga antibodies in protection against influenza
    • PMID:2251874
    • Tamura S, Funato H, Hirabayashi Y, Kikuta K, Suzuki Y, Nagamine T, et al. Functional role of respiratory tract haemagglutinin-specific IgA antibodies in protection against influenza. Vaccine 1990; 8:479-85; PMID:2251874; http://dx.doi.org/10.1016/0264-410X(90)90250-P
    • (1990) Vaccine , vol.84 , pp. 79-85
    • Tamura, S.1    Funato, H.2    Hirabayashi, Y.3    Kikuta, K.4    Suzuki, Y.5    Nagamine, T.6
  • 5
    • 0025859339 scopus 로고
    • Cross-protection against influenza a virus infection by passively transferred respiratory tract iga antibodies to different hemagglutinin molecules
    • PMID:1646112
    • Tamura S, Funato H, Hirabayashi Y, Suzuki Y, Nagamine T, Aizawa C, et al. Cross-protection against influenza A virus infection by passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules. Eur J Immunol 1991; 21:1337-44; PMID:1646112; http://dx.doi.org/10.1002/eji.1830210602
    • (1991) Eur J Immunol , vol.21 , pp. 1337-1344
    • Tamura, S.1    Funato, H.2    Hirabayashi, Y.3    Suzuki, Y.4    Nagamine, T.5    Aizawa, C.6
  • 6
    • 0037087336 scopus 로고    scopus 로고
    • Protection against influenza virus infection in polymeric ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines
    • PMID:11884464
    • Asahi Y, Yoshikawa T, Watanabe I, Iwasaki T, Hasegawa H, Sato Y, et al. Protection against influenza virus infection in polymeric Ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines. J Immunol 2002; 168:2930-8; PMID:11884464
    • (2002) J Immunol , vol.168 , pp. 2930-2938
    • Asahi, Y.1    Yoshikawa, T.2    Watanabe, I.3    Iwasaki, T.4    Hasegawa, H.5    Sato, Y.6
  • 7
    • 4344613346 scopus 로고    scopus 로고
    • Secretory iga antibodies provide cross-protection against infection with different strains of influenza b virus
    • PMID:15332283
    • Asahi-Ozaki Y, Yoshikawa T, Iwakura Y, Suzuki Y, Tamura S, Kurata T, et al. Secretory IgA antibodies provide cross-protection against infection with different strains of influenza B virus. J Med Virol 2004; 74:328-35; PMID:15332283; http://dx.doi.org/10.1002/jmv.20173
    • (2004) J Med Virol , vol.74 , pp. 328-335
    • Asahi-Ozaki, Y.1    Yoshikawa, T.2    Iwakura, Y.3    Suzuki, Y.4    Tamura, S.5    Kurata, T.6
  • 8
    • 12444254796 scopus 로고    scopus 로고
    • Roles of anti-hemagglutinin iga and igg antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia
    • PMID:12744867
    • Ito R, Ozaki YA, Yoshikawa T, Hasegawa H, Sato Y, Suzuki Y, et al. Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia. Vaccine 2003; 21:2362-71; PMID:12744867; http://dx.doi.org/10.1016/S0264- 410X(03)00078-1
    • (2003) Vaccine , vol.21 , pp. 2362-2371
    • Ito, R.1    Ozaki, Y.A.2    Yoshikawa, T.3    Hasegawa, H.4    Sato, Y.5    Suzuki, Y.6
  • 9
    • 3242765120 scopus 로고    scopus 로고
    • Role of iga versus igg in the control of influenza viral infection in the murine respiratory tract
    • PMID:15265932
    • Renegar KB, Small PA Jr., Boykins LG, Wright PF. Role of IgA versus IgG in the control of influenza viral infection in the murine respiratory tract. J Immunol 2004; 173:1978-86; PMID:15265932
    • (2004) J Immunol , vol.173 , pp. 1978-1986
    • Renegar, K.B.1    Small Jr., P.A.2    Boykins, L.G.3    Wright, P.F.4
  • 10
    • 13844313860 scopus 로고    scopus 로고
    • Defense mechanisms against influenza virus infection in the respiratory tract mucosa
    • PMID:15623947
    • Tamura S, Kurata T. Defense mechanisms against influenza virus infection in the respiratory tract mucosa. Jpn J Infect Dis 2004; 57:236-47; PMID:15623947
    • (2004) Jpn J Infect Dis , vol.57 , pp. 236-247
    • Tamura, S.1    Kurata, T.2
  • 11
    • 0035825603 scopus 로고    scopus 로고
    • Ensuring vaccine safety in immunization programmes-A who perspective
    • PMID:11166881
    • Jodar L, Duclos P, Milstien JB, Griffiths E, Aguado MT, Clements CJ. Ensuring vaccine safety in immunization programmes-A WHO perspective. Vaccine 2001; 19:1594-605; PMID:11166881; http://dx.doi.org/10.1016/S0264-410X(00)00358- 3
    • (2001) Vaccine , vol.19 , pp. 1594-1605
    • Jodar, L.1    Duclos, P.2    Milstien, J.B.3    Griffiths, E.4    Aguado, M.T.5    Clements, C.J.6
  • 12
    • 0027944905 scopus 로고
    • Developments in mucosal influenza virus vaccines
    • PMID:7856295
    • Kuno-Sakai H, Kimura M, Ohta K, Shimojima R, Oh Y, Fukumi H. Developments in mucosal influenza virus vaccines. Vaccine 1994; 12:1303-10; PMID:7856295; http://dx.doi.org/10.1016/S0264-410X(94)80056-6
    • (1994) Vaccine , vol.12 , pp. 1303-1310
    • Kuno-Sakai, H.1    Kimura, M.2    Ohta, K.3    Shimojima, R.4    Oh, Y.5    Fukumi, H.6
  • 13
    • 0029959974 scopus 로고    scopus 로고
    • Antibody responses in volunteers induced by nasal influenza vaccine combined with escherichia coli heat-labile enterotoxin b subunit containing a trace amount of the holotoxin
    • PMID:8852406
    • Hashigucci K, Ogawa H, Ishidate T, Yamashita R, Kamiya H, Watanabe K, et al. Antibody responses in volunteers induced by nasal influenza vaccine combined with Escherichia coli heat-labile enterotoxin B subunit containing a trace amount of the holotoxin. Vaccine 1996; 14:113-9; PMID:8852406; http://dx.doi.org/10.1016/0264-410X(95)00174-Y
    • (1996) Vaccine , vol.14 , pp. 113-119
    • Hashigucci, K.1    Ogawa, H.2    Ishidate, T.3    Yamashita, R.4    Kamiya, H.5    Watanabe, K.6
  • 14
    • 0034085917 scopus 로고    scopus 로고
    • Local and systemic immune response in community-dwelling elderly after intranasal or intramuscular immunization with inactivated influenza vaccine
    • PMID:10745240
    • Muszkat M, Yehuda AB, Schein MH, Friedlander Y, Naveh P, Greenbaum E, et al. Local and systemic immune response in community-dwelling elderly after intranasal or intramuscular immunization with inactivated influenza vaccine. J Med Virol 2000; 61:100-6; PMID:10745240; http://dx.doi.org/10.1002/(SICI)1096- 9071(200005)61:1;100::AIDJMV16;
    • (2000) J Med Virol , vol.61 , pp. 100-106
    • Muszkat, M.1    Yehuda, A.B.2    Schein, M.H.3    Friedlander, Y.4    Naveh, P.5    Greenbaum, E.6
  • 15
    • 0037081380 scopus 로고    scopus 로고
    • Mucosal [siga] and serum [igg] immunologic responses in the community after a single intra-nasal immunization with a new inactivated trivalent influenza vaccine
    • PMID:11803086
    • Greenbaum E, Furst A, Kiderman A, Stewart B, Levy R, Schlesinger M, et al. Mucosal [SIgA] and serum [IgG] immunologic responses in the community after a single intra-nasal immunization with a new inactivated trivalent influenza vaccine. Vaccine 2002; 20:1232-9; PMID:11803086; http://dx.doi.org/10.1016/ S0264-410X(01)00396-6
    • (2002) Vaccine , vol.20 , pp. 1232-1239
    • Greenbaum, E.1    Furst, A.2    Kiderman, A.3    Stewart, B.4    Levy, R.5    Schlesinger, M.6
  • 16
    • 2942558585 scopus 로고    scopus 로고
    • Mucosal (siga) and serum (igg) immunologic responses in young adults following intranasal administration of one or two doses of inactivated, trivalent anti-influenza vaccine
    • PMID:15193382
    • Greenbaum E, Engelhard D, Levy R, Schlezinger M, Morag A, Zakay-Rones Z. Mucosal (SIgA) and serum (IgG) immunologic responses in young adults following intranasal administration of one or two doses of inactivated, trivalent anti-influenza vaccine. Vaccine 2004; 22:2566-77; PMID:15193382; http://dx.doi.org/10.1016/j.vaccine.2003.12.018
    • (2004) Vaccine , vol.22 , pp. 2566-2577
    • Greenbaum, E.1    Engelhard, D.2    Levy, R.3    Schlezinger, M.4    Morag, A.5    Zakay-Rones, Z.6
  • 17
    • 0348078299 scopus 로고    scopus 로고
    • Mucosal antibody response induced with a nasal virosome-based influenza vaccine
    • PMID:14505915
    • Durrer P, Glück U, Spyr C, Lang AB, Zurbriggen R, Herzog C, et al. Mucosal antibody response induced with a nasal virosome-based influenza vaccine. Vaccine 2003; 21:4328-34; PMID:14505915; http://dx.doi.org/10.1016/S0264- 410X(03)00457-2
    • (2003) Vaccine , vol.21 , pp. 4328-4334
    • Durrer, P.1    Glück, U.2    Spyr, C.3    Lang, A.B.4    Zurbriggen, R.5    Herzog, C.6
  • 18
    • 29044438039 scopus 로고    scopus 로고
    • Intranasal administration of a proteosome-influenza vaccine is well-Tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects
    • PMID:16129526
    • Treanor J, Nolan C, O'Brien D, Burt D, Lowell G, Linden J, et al. Intranasal administration of a proteosome-influenza vaccine is well-Tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects. Vaccine 2006; 24:254-62; PMID:16129526; http://dx.doi.org/10.1016/j. vaccine.2005.07.088
    • (2006) Vaccine , vol.24 , pp. 254-262
    • Treanor, J.1    Nolan, C.2    O'Brien, D.3    Burt, D.4    Lowell, G.5    Linden, J.6
  • 19
    • 34250800842 scopus 로고    scopus 로고
    • A dose-response evaluation of inactivated influenza vaccine given intranasally and intramuscularly to healthy young adults
    • PMID:17559990
    • Atmar RL, Keitel WA, Cate TR, Munoz FM, Ruben F, Couch RB. A dose-response evaluation of inactivated influenza vaccine given intranasally and intramuscularly to healthy young adults. Vaccine 2007; 25:5367-73; PMID:17559990; http://dx.doi.org/10.1016/j.vaccine.2007.05.002
    • (2007) Vaccine , vol.25 , pp. 5367-5373
    • Atmar, R.L.1    Keitel, W.A.2    Cate, T.R.3    Munoz, F.M.4    Ruben, F.5    Couch, R.B.6
  • 20
    • 13944257660 scopus 로고    scopus 로고
    • Synthetic double-stranded rna poly(i:C) combined with mucosal vaccine protects against influenza virus infection
    • PMID:15709010
    • Ichinohe T, Watanabe I, Ito S, Fujii H, Moriyama M, Tamura S, et al. Synthetic double-stranded RNA poly(I:C) combined with mucosal vaccine protects against influenza virus infection. J Virol 2005; 79:2910-9; PMID:15709010; http://dx.doi.org/10.1128/JVI.79.5.2910-2919.2005
    • (2005) J Virol , vol.79 , pp. 2910-2919
    • Ichinohe, T.1    Watanabe, I.2    Ito, S.3    Fujii, H.4    Moriyama, M.5    Tamura, S.6
  • 21
    • 38449123291 scopus 로고    scopus 로고
    • Cross-protection against h5n1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine
    • PMID:17922395
    • Ichinohe T, Tamura S, Kawaguchi A, Ninomiya A, Imai M, Itamura S, et al. Cross-protection against H5N1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine. J Infect Dis 2007; 196:1313-20; PMID:17922395; http://dx.doi.org/10.1086/521304
    • (2007) J Infect Dis , vol.196 , pp. 1313-1320
    • Ichinohe, T.1    Tamura, S.2    Kawaguchi, A.3    Ninomiya, A.4    Imai, M.5    Itamura, S.6
  • 25
    • 84874674301 scopus 로고    scopus 로고
    • Correlates of protection to influenza virus, where do we go from here?
    • In press; PMID:23291930
    • Cox RJ. Correlates of protection to influenza virus, where do we go from here? Hum Vaccin Immunother 2013; 9: In press; PMID:23291930; http://dx.doi.org/10.4161/hv.22908.
    • (2013) Hum Vaccin Immunother , pp. 9
    • Cox, R.J.1
  • 26
    • 26844454091 scopus 로고    scopus 로고
    • Mechanisms of broad cross-protection provided by influenza virus infection and their application to vaccines
    • PMID:16116250
    • Tamura S, Tanimoto T, Kurata T. Mechanisms of broad cross-protection provided by influenza virus infection and their application to vaccines. Jpn J Infect Dis 2005; 58:195-207; PMID:16116250
    • (2005) Jpn J Infect Dis , vol.58 , pp. 195-207
    • Tamura, S.1    Tanimoto, T.2    Kurata, T.3
  • 27
    • 77955654274 scopus 로고    scopus 로고
    • Studies on the usefulness of intranasal inactivated influenza vaccines
    • PMID:20493820
    • Tamura S. Studies on the usefulness of intranasal inactivated influenza vaccines. Vaccine 2010; 28:6393-7; PMID:20493820; http://dx.doi.org/10.1016/j. vaccine.2010.05.019
    • (2010) Vaccine , vol.28 , pp. 6393-6397
    • Tamura, S.1
  • 28
    • 0025324564 scopus 로고
    • Rapid focus reduction neutralization test of influenza a and b viruses in microtiter system
    • PMID:2380359
    • Okuno Y, Tanaka K, Baba K, Maeda A, Kunita N, Ueda S. Rapid focus reduction neutralization test of influenza A and B viruses in microtiter system. J Clin Microbiol 1990; 28:1308-13; PMID:2380359
    • (1990) J Clin Microbiol , vol.28 , pp. 1308-1313
    • Okuno, Y.1    Tanaka, K.2    Baba, K.3    Maeda, A.4    Kunita, N.5    Ueda, S.6
  • 29
    • 0019935856 scopus 로고
    • Failure to detect hemagglutination-inhibiting antibodies with intact avian influenza virions
    • PMID:6292104
    • Lu BL, Webster RG, Hinshaw VS. Failure to detect hemagglutination- inhibiting antibodies with intact avian influenza virions. Infect Immun 1982; 38:530-5; PMID:6292104
    • (1982) Infect Immun , vol.38 , pp. 530-535
    • Lu, B.L.1    Webster, R.G.2    Hinshaw, V.S.3
  • 30
    • 0033041241 scopus 로고    scopus 로고
    • Detection of antibody to avian influenza a (h5n1) virus in human serum by using a combination of serologic assays
    • PMID:10074505
    • Rowe T, Abernathy RA, Hu-Primmer J, Thompson WW, Lu X, Lim W, et al. Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays. J Clin Microbiol 1999; 37:937-43; PMID:10074505
    • (1999) J Clin Microbiol , vol.37 , pp. 937-943
    • Rowe, T.1    Abernathy, R.A.2    Hu-Primmer, J.3    Thompson, W.W.4    Lu, X.5    Lim, W.6
  • 31
    • 83655180837 scopus 로고    scopus 로고
    • Characterization of neutralizing antibodies in adults after intranasal vaccination with an inactivated influenza vaccine
    • PMID:22170556
    • Ainai A, Tamura S, Suzuki T, Ito R, Asanuma H, Tanimoto T, et al. Characterization of neutralizing antibodies in adults after intranasal vaccination with an inactivated influenza vaccine. J Med Virol 2012; 84:336-44; PMID:22170556; http://dx.doi.org/10.1002/jmv.22273
    • (2012) J Med Virol , vol.84 , pp. 336-344
    • Ainai, A.1    Tamura, S.2    Suzuki, T.3    Ito, R.4    Asanuma, H.5    Tanimoto, T.6
  • 32
    • 0023507406 scopus 로고
    • And serum type iga in nasal secretion and antibody activity against the m protein
    • PMID:3304089
    • Kurono Y, Mogi G. Secretory IgA and serum type IgA in nasal secretion and antibody activity against the M protein. Ann Otol Rhinol Laryngol 1987; 96:419-24; PMID:3304089
    • (1987) Ann Otol Rhinol Laryngol , vol.96 , pp. 419-424
    • Kurono, Y.1    Mogi, G.2    Secretory, IgA.3
  • 33
    • 0038120851 scopus 로고    scopus 로고
    • Intranasal immunization with formalin-inactivated virus vaccine induces a broad spectrum of heterosubtypic immunity against influenza a virus infection in mice
    • PMID:12804850
    • Takada A, Matsushita S, Ninomiya A, Kawaoka Y, Kida H. Intranasal immunization with formalin-inactivated virus vaccine induces a broad spectrum of heterosubtypic immunity against influenza A virus infection in mice. Vaccine 2003; 21:3212-8; PMID:12804850; http://dx.doi.org/10.1016/S0264-410X(03)00234-2
    • (2003) Vaccine , vol.21 , pp. 3212-3218
    • Takada, A.1    Matsushita, S.2    Ninomiya, A.3    Kawaoka, Y.4    Kida, H.5
  • 34
    • 76649094925 scopus 로고    scopus 로고
    • Estimation of the effective doses of nasal-inactivated influenza vaccine in humans from mouse-model experiments
    • PMID:20093755
    • Tamura S, Hasegawa H, Kurata T. Estimation of the effective doses of nasal-inactivated influenza vaccine in humans from mouse-model experiments. Jpn J Infect Dis 2010; 63:8-15; PMID:20093755
    • (2010) Jpn J Infect Dis , vol.63 , pp. 8-15
    • Tamura, S.1    Hasegawa, H.2    Kurata, T.3
  • 35
    • 1842631428 scopus 로고    scopus 로고
    • Recognition of single-stranded rna viruses by toll-like receptor 7
    • PMID:15034168
    • Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, et al. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A 2004; 101:5598-603; PMID:15034168; http://dx.doi.org/10.1073/ pnas.0400937101
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5598-5603
    • Lund, J.M.1    Alexopoulou, L.2    Sato, A.3    Karow, M.4    Adams, N.C.5    Gale, N.W.6
  • 36
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of tlr7-mediated recognition of single-stranded rna
    • PMID:14976261
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004; 303:1529-31; PMID:14976261; http://dx.doi.org/10.1126/science.1093616
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis Sousa E, C.5
  • 37
    • 4444381770 scopus 로고    scopus 로고
    • Intranasal immunization with inactivated influenza virus enhances immune responses to coadministered simian-human immunodeficiency virus-like particle antigens
    • PMID:15331695
    • Kang SM, Guo L, Yao Q, Skountzou I, Compans RW. Intranasal immunization with inactivated influenza virus enhances immune responses to coadministered simian-human immunodeficiency virus-like particle antigens. J Virol 2004; 78:9624-32; PMID:15331695; http://dx.doi.org/10.1128/JVI.78.18.9624-9632.2004
    • (2004) J Virol , vol.78 , pp. 9624-96332
    • Kang, S.M.1    Guo, L.2    Yao, Q.3    Skountzou, I.4    Compans, R.W.5
  • 38
    • 77952982038 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes
    • PMID:20424013
    • Koyama S, Aoshi T, Tanimoto T, Kumagai Y, Kobiyama K, Tougan T, et al. Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes. Sci Transl Med 2010; 2:25ra24; PMID:20424013; http://dx.doi.org/10. 1126/scitranslmed.3000759
    • (2010) Sci Transl Med , vol.2
    • Koyama, S.1    Aoshi, T.2    Tanimoto, T.3    Kumagai, Y.4    Kobiyama, K.5    Tougan, T.6
  • 39
    • 0022645934 scopus 로고
    • Resistance of adults to challenge with influenza a wildtype virus after receiving live or inactivated virus vaccine
    • PMID:3700611
    • Clements ML, Betts RF, Tierney EL, Murphy BR. Resistance of adults to challenge with influenza A wildtype virus after receiving live or inactivated virus vaccine.J Clin Microbiol 1986; 23:73-6; PMID:3700611
    • (1986) J Clin Microbiol , vol.23 , pp. 73-76
    • Clements, M.L.1    Betts, R.F.2    Tierney, E.L.3    Murphy, B.R.4
  • 40
    • 0022588771 scopus 로고
    • Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza a wild-Type virus
    • PMID:3722363
    • Clements ML, Betts RF, Tierney EL, Murphy BR. Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-Type virus. J Clin Microbiol 1986; 24:157-60; PMID:3722363
    • (1986) J Clin Microbiol , vol.24 , pp. 157-160
    • Clements, M.L.1    Betts, R.F.2    Tierney, E.L.3    Murphy, B.R.4
  • 41
    • 0034083593 scopus 로고    scopus 로고
    • Correlates of immune protection induced by live, attenuated, cold-Adapted, trivalent, intranasal influenza virus vaccine
    • PMID:10720541
    • Belshe RB, Gruber WC, Mendelman PM, Mehta HB, Mahmood K, Reisinger K, et al. Correlates of immune protection induced by live, attenuated, cold-Adapted, trivalent, intranasal influenza virus vaccine. J Infect Dis 2000; 181:1133-7; PMID:10720541; http://dx.doi.org/10.1086/315323
    • (2000) J Infect Dis , vol.181 , pp. 1133-1137
    • Belshe, R.B.1    Gruber, W.C.2    Mendelman, P.M.3    Mehta, H.B.4    Mahmood, K.5    Reisinger, K.6
  • 42
    • 0019427596 scopus 로고
    • Hemagglutinin-specific enzyme-linked immunosorbent assay for antibodies to influenza a and b viruses
    • PMID:7240388
    • Murphy BR, Phelan MA, Nelson DL, Yarchoan R, Tierney EL, Alling DW, et al. Hemagglutinin-specific enzyme-linked immunosorbent assay for antibodies to influenza A and B viruses. J Clin Microbiol 1981; 13:554-60; PMID:7240388
    • (1981) J Clin Microbiol , vol.13 , pp. 554-560
    • Murphy, B.R.1    Phelan, M.A.2    Nelson, D.L.3    Yarchoan, R.4    Tierney, E.L.5    Alling, D.W.6
  • 43
    • 67650679858 scopus 로고    scopus 로고
    • Protective immunity afforded by inactivated h5n1 (nibrg-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice
    • PMID:19385735
    • Takahashi Y, Hasegawa H, Hara Y, Ato M, Ninomiya A, Takagi H, et al. Protective immunity afforded by inactivated H5N1 (NIBRG-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice. J Infect Dis 2009; 199:1629-37; PMID:19385735; http://dx.doi.org/10.1086/598954
    • (2009) J Infect Dis , vol.199 , pp. 1629-1637
    • Takahashi, Y.1    Hasegawa, H.2    Hara, Y.3    Ato, M.4    Ninomiya, A.5    Takagi, H.6
  • 44
    • 0030469344 scopus 로고    scopus 로고
    • The hemagglutination inhibition antibody responses to an inactivated influenza vaccine among healthy adults: With special reference to the prevaccination antibody and its interaction with age
    • PMID:9032887
    • Hirota Y, Kaji M, Ide S, Goto S, Oka T. The hemagglutination inhibition antibody responses to an inactivated influenza vaccine among healthy adults: with special reference to the prevaccination antibody and its interaction with age. Vaccine 1996; 14:1597-602; PMID:9032887; http://dx.doi.org/10.1016/S0264- 410X(96)00153-3
    • (1996) Vaccine , vol.14 , pp. 1597-1602
    • Hirota, Y.1    Kaji, M.2    Ide, S.3    Goto, S.4    Oka, T.5
  • 45
    • 0016801782 scopus 로고
    • Plaque assay and primary isolation of influenza a viruses in an established line of canine kidney cells (mdck) in the presence of trypsin
    • PMID:1214709
    • Tobita K, Sugiura A, Enomote C, Furuyama M. Plaque assay and primary isolation of influenza A viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin. Med Microbiol Immunol 1975; 162:9-14; PMID:1214709; http://dx.doi.org/10.1007/BF02123572
    • (1975) Med Microbiol Immunol , vol.16 , pp. 29-14
    • Tobita, K.1    Sugiura, A.2    Enomote, C.3    Furuyama, M.4
  • 46
    • 0034659609 scopus 로고    scopus 로고
    • Protection against influenza virus infection in mice immunized by administration of hemagglutinin-expressing dnas with electroporation
    • PMID:10812219
    • Kadowaki S, Chen Z, Asanuma H, Aizawa C, Kurata T, Tamura S. Protection against influenza virus infection in mice immunized by administration of hemagglutinin-expressing DNAs with electroporation. Vaccine 2000; 18:2779-88; PMID:10812219; http://dx.doi.org/10.1016/S0264-410X(00)00087-6
    • (2000) Vaccine , vol.18 , pp. 2779-2788
    • Kadowaki, S.1    Chen, Z.2    Asanuma, H.3    Aizawa, C.4    Kurata, T.5    Tamura, S.6
  • 47
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoint
    • Reed LJ, Muench H. A simple method of estimating fifty per cent endpoint. Am J Hyg 1938; 27:493-7
    • (1938) Am J Hyg , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 48
    • 0001925693 scopus 로고
    • Comparisons of serologic and febrile responses in humans to vaccination with influenza a viruses or their hemagglutinins
    • PMID:14102904
    • Davenport FM, Hennessy AV, Brandon FM, Webster RG, Barrett CD Jr., Lease GO. Comparisons of Serologic and Febrile Responses in Humans to Vaccination with Influenza a Viruses or Their Hemagglutinins. J Lab Clin Med 1964; 63:5-13; PMID:14102904
    • (1964) J Lab Clin Med , vol.63 , pp. 5-13
    • Davenport, F.M.1    Hennessy, A.V.2    Brandon, F.M.3    Webster, R.G.4    Barrett Jr., C.D.5    Lease, G.O.6
  • 49
    • 0014605412 scopus 로고
    • Standardized viral hemagglutination and hemagglutination-inhibition tests. II. Description and statistical evaluation
    • PMID:4984203
    • Hierholzer JC, Suggs MT, Hall EC. Standardized viral hemagglutination and hemagglutination-inhibition tests. II. Description and statistical evaluation. Appl Microbiol 1969; 18:824-33; PMID:4984203
    • (1969) Appl Microbiol , vol.18 , pp. 824-833
    • Hierholzer, J.C.1    Suggs, M.T.2    Hall, E.C.3
  • 50
    • 0019181970 scopus 로고
    • Purification of influenza virus glycoproteins for the preparation and standardization of immunological potency testing reagents
    • PMID:7410447
    • Phelan MA, Mayner RE, Bucher DJ, Ennis FA. Purification of influenza virus glycoproteins for the preparation and standardization of immunological potency testing reagents. J Biol Stand 1980; 8:233-42; PMID:7410447; http://dx.doi.org/10.1016/S0092-1157(80)80039-4
    • (1980) J Biol Stand , vol.82 , pp. 33-42
    • Phelan, M.A.1    Mayner, R.E.2    Bucher, D.J.3    Ennis, F.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.