PCR-based screening for the most prevalent alpha 1 antitrypsin deficiency mutations (PI S, Z, and Mmalton) in COPD patients from Eastern Tunisia

Biochemical Genetics

Volumn 51, Issue 9-10, 2013, Pages 677-685

  Denden, Sabri ^a,c   Lakhdar, Ramzi ^a   Boudawara Keskes, Nadia ^b   Hamdaoui, Mohamed Hedi ^c   Chibani, Jemni Ben ^a   Khelil, Amel Haj ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b CHU Tahar Sfar   (Tunisia)

^c University of Tunis El Manar   (Tunisia)

Author keywords

Alpha 1 antitrypsin mutations; Heteroduplex DNA; RFLP PCR

Indexed keywords

PROTEINASE INHIBITOR;

ALLELE; ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PREVALENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SOUTHERN EUROPE; TUNISIA;

ALLELES; ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; GENETIC VARIATION; GENOTYPING TECHNIQUES; HUMANS; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREVALENCE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TUNISIA;

EID: 84884607276     PISSN: 00062928     EISSN: 15734927     Source Type: Journal    
DOI: 10.1007/s10528-013-9597-6     Document Type: Article

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