G protein-cAMP signaling pathway mediated by PGA3 plays different roles in regulating the expressions of amylases and cellulases in Penicillium decumbens

Fungal Genetics and Biology

Volumn 58-59, Issue , 2013, Pages 62-70

  Hu, Yibo ^a   Liu, Guodong ^a   Li, Zhonghai ^a   Qin, Yuqi ^a   Qu, Yinbo ^a   Song, Xin ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Amylase; CAMP; Cellulase; G protein; Penicillium decumbens

Indexed keywords

AMYLASE; CELLULASE; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PROTEIN AMYR; PROTEIN PGA3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMY15A GENE; ARTICLE; CARBON SOURCE; CEL7A 2 GENE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; FUNGAL GENE; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS GROWTH; GENE DELETION; GENETIC TRANSCRIPTION; MORPHOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIUM; PENICILLIUM DECUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING; SUPPLEMENTATION;

FUNGI; PENICILLIUM DECUMBENS;

AMYLASE; CAMP; CELLULASE; G PROTEIN; PENICILLIUM DECUMBENS;

AMYLASES; CELLULASES; CYCLIC AMP; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; GTP-BINDING PROTEIN ALPHA SUBUNITS; PENICILLIUM; SIGNAL TRANSDUCTION;

EID: 84884589763     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2013.08.002     Document Type: Article

References (45)

1. Aro N., Saloheimo A., Ilmén M., Penttilä M. ACEII, a novel transcriptional activator involved in regulation of cellulase and xylanase genes of Trichoderma reesei. J. Biol. Chem. 2001, 276:24309-24314.
2. Aro N., Pakula T., Penttilä M. Transcriptional regulation of plant cell wall degradation by filamentous fungi. FEMS Microbiol. Rev. 2006, 29:719-739.
3. Bhella R.S., Altosaar I. Role of cAMP in the mediation of glucose catabolite repression of glucoamylase synthesis in Aspergillus awamori. Curr. Genet. 1988, 14:247-252.
4. Bölker M. Sex and crime: heterotrimeric G proteins in fungal mating and pathogenesis. Fungal Genet. Biol. 1998, 25:143-156.
5. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
6. Chang M.H., Chae K.S., Han D.M., Jahng K.Y. The GanB Galpha-protein negatively regulates asexual sporulation and plays a positive role in conidial germination in Aspergillus nidulans. Genetics 2004, 167:1305-1315.
7. Coutinho P.M., Andersen M.R., Kolenova K., vanKuyk P.A., Benoit I., Gruben B.S., Trejo-Aguilar B., Visser H., Solingen P.v., Pakula T., Seiboth B., Battaglia E., Aguilar-Osorio G., de Jong J.F., Ohm R.A., Aguilar M., Henrissat B., Nielsen J., Stålbrand H., de Vries R.P. Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae. Fungal Genet. Biol. 2009, 46:161-169.
8. Foreman P.K., Brown D., Dankmeyer L., Dean R., Diener S., Dunn-Coleman N.S., Goedegebuur F., Houfek T.D., England G.J., Kelley A.S. Transcriptional regulation of biomass-degrading enzymes in the filamentous fungus Trichoderma reesei. J. Biol. Chem. 2003, 278:31988-31997.
9. García-Rico R.O., Chávez R., Fierro F., Martín J.F. Effect of a heterotrimeric G protein alpha subunit on conidia germination, stress response, and roquefortine C production in Penicillium roqueforti. Int. Microbiol. 2010, 12:123-129.
10. Gomi K., Akeno T., Minetoki T., Ozeki K., Kumagai C., Okazaki N., Iimura Y. Molecular cloning and characterization of a transcriptional activator gene, amyR, involved in the amylolytic gene expression inAspergillus oryzae. Biosci. Biotechnol. Biochem. 2000, 64:816-827.
11. Gruber F., Visser J., Kubicek C., Graaff L.H. The development of a heterologous transformation system for the cellulolytic fungus Trichoderma reesei based on a pyrG-negative mutant strain. Curr. Genet. 1990, 18:71-76.
12. Ilmen M., Onnela M.L., Klemsdal S., Keränen S., Penttilä M. Functional analysis of the cellobiohydrolase I promoter of the filamentous fungus Trichoderma reesei. Mol. Gen. Genet. 1996, 253:303-314.
13. Kays A.M., Rowley P.S., Baasiri R.A., Borkovich K.A. Regulation of conidiation and adenylyl cyclase levels by the Gα protein GNA-3 in Neurospora crassa. Mol. Cell. Biol. 2000, 20:7693-7705.
14. Kubicek C.P., Mikus M., Schuster A., Schmoll M., Seiboth B. Metabolic engineering strategies for the improvement of cellulase production by Hypocrea jecorina. Biotechnol. Biofuels 2009, 2:19.
15. Kubodera T., Yamashita N., Nishimura A. Transformation of Aspergillus sp. and Trichoderma reesei using the pyrithiamine resistance gene (ptrA) of Aspergillus oryzae. Biosci. Biotechnol. Biochem. 2002, 66:404-406.
16. Lafon A., Seo J.A., Han K.H., Yu J.H., d'Enfert C. The heterotrimeric G-protein GanB (α)-SfaD (β)-GpgA (γ) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans. Genetics 2005, 171:71-80.
17. Li L., Wright S.J., Krystofova S., Park G., Borkovich K.A. Heterotrimeric G protein signaling in filamentous fungi. Annu. Rev. Microbiol. 2007, 61:423-452.
18. Li Z., Du C., Zhong Y., Wang T. Development of a highly efficient gene targeting system allowing rapid genetic manipulations in Penicillium decumbens. Appl. Microbiol. Biotechnol. 2010, 87:1065-1076.
19. Liu G., Zhang L., Qin Y., Zou G., Li Z., Yan X., Wei X., Chen M., Chen L., Zheng K., Zhang J., Ma L., Li J., Liu R., Xu H., Bao X., Fang X., Wang L., Zhong Y., Liu W., Zheng H., Wang S., Wang C., Xun L., Zhao G.P., Wang T., Zhou Z., Qu Y. Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes. Sci. Rep. 2013, 3:1569.
20. Liu G., Zhang L., Wei X., Zou G., Qin Y., Ma L., Li J., Zheng H., Wang S., Wang C., Xun L., Zhao G.P., Zhou Z., Qu Y. Genomic and secretomic analyses reveal unique features of the lignocellulolytic enzyme system of Penicillium decumbens. PLoS ONE 2013, 8:55185.
21. Mo H., Zhang X., Li Z. Control of gas phase for enhanced cellulase production by Penicillium decumbens in solid-state culture. Process Biochem. 2004, 39:1293-1297.
22. Oda K., Kakizono D., Yamada O., Iefuji H., Akita O., Iwashita K. Proteomic analysis of extracellular proteins from Aspergillus oryzae grown under submerged and solid-state culture conditions. Appl. Environ. Microbiol. 2006, 72:3448-3457.
23. Penttilä M., Nevalainen H., Rättö M., Salminen E., Knowles J. A versatile transformation system for the cellulolytic filamentous fungus Trichoderma reesei. Gene 1987, 61:155-164.
24. 2 transcription factor involved in regulation of activity of the cellulase promoter cbh1 of Trichoderma reesei. J. Biol. Chem. 2000, 275:5817-5825.
25. Schmoll M., Schuster A., Silva Rdo N., Kubicek C.P. The G-alpha protein GNA3 of Hypocrea jecorina (anamorph Trichoderma reesei) regulates cellulase gene expression in the presence of light. Eukaryot. Cell 2009, 8:410-420.
26. Schuster A., Tisch D., Seidl-Seiboth V., Kubicek C.P., Schmoll M. Roles of protein kinase A and adenylate cyclase in light-modulated cellulase regulation in Trichoderma reesei. Appl. Environ. Microbiol. 2012, 78:2168-2178.
27. Seibel C., Gremel G., do Nascimento Silva R., Schuster A., Kubicek C.P., Schmoll M. Light-dependent roles of the G-protein alpha subunit GNA1 of Hypocrea jecorina (anamorph Trichoderma reesei). BMC Biol. 2009, 7:58.
28. Šesták S., Farkaš V. Metabolic regulation of endoglucanase synthesis in Trichoderma reesei: participation of cyclic AMP and glucose-6-phosphate. Can. J. Microbiol. 1993, 39:342-347.
29. Sun X., Liu Z., Qu Y., Li X. The effects of wheat bran composition on the production of biomass-hydrolyzing enzymes by Penicillium decumbens. Appl. Biochem. Biotechnol. 2008, 146:119-128.
30. Sun X., Liu Z., Zheng K., Song X., Qu Y. The composition of basal and induced cellulase systems in Penicillium decumbens under induction or repression conditions. Enzyme Microb. Technol. 2008, 42:560-567.
31. Tisch D., Kubicek C.P., Schmoll M. New insights into the mechanism of light modulated signaling by heterotrimeric G-proteins: ENVOY acts on gna1 and gna3 and adjusts cAMP levels in Trichoderma reesei (Hypocrea jecorina). Fungal Genet. Biol. 2011, 48:631-640.
32. Tsukagoshi N., Kobayashi T., Kato M. Regulation of the amylolytic and (hemi-) cellulolytic genes in aspergilli. J. Gen. Appl. Microbiol. 2001, 47:1-19.
33. van Peij N.N., Gielkens M.M., de Vries R.P., Visser J., de Graaff L.H. The transcriptional activator XlnR regulates both xylanolytic and endoglucanase gene expression in Aspergillus niger. Appl. Environ. Microbiol. 1998, 64:3615-3619.
34. Vogel H. A convenient growth medium forNeurospora (medium N). Microb. Genet. Bull. 1956, 13:42-43.
35. Wang P., Nuss D.L. Induction of a Cryphonectria parasitica cellobiohydrolase I gene is suppressed by hypovirus infection and regulated by a GTP-binding-protein-linked signaling pathway involved in fungal pathogenesis. Proc. Natl. Acad. Sci. USA 1995, 92:11529-11533.
36. Wang D., Qu Y., Gao P. Regulation of cellulase synthesis in mycelial fungi: Participation of ATP and cyclic AMP. Biotechnol. Lett. 1995, 17:593-598.
37. Wei X., Zheng K., Chen M., Liu G., Li J., Lei Y., Qin Y., Qu Y. Transcription analysis of lignocellulolytic enzymes of Penicillium decumbens 114-2 and its catabolite-repression-resistant mutant. C. R. Bio. 2011, 334:806-811.
38. Wilkie T.M., Yokoyama S. Evolution of the G protein alpha subunit multigene family. Soc. Gen. Physiol. Ser. 1994, 49:249-270.
39. Wood T.M., Bhat K.M. Methods for measuring cellulase activities. Methods Enzymol. 1988, 160:87-112.
40. Yu J.H. Heterotrimeric G protein signaling and RGSs inAspergillus nidulans. J. Microbiol. 2006, 44:145-154.
41. Yu J.H., Hamari Z., Han K.H., Seo J.A., Reyes-Domínguez Y., Scazzocchio C. Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi. Fungal Genet. Biol. 2004, 41:973-981.
42. Zeilinger S., Ebner A., Marosits T., Mach R., Kubicek C. The Hypocrea jecorina HAP 2/3/5 protein complex binds to the inverted CCAAT-box (ATTGG) within the cbh2 (cellobiohydrolase II-gene) activating element. Mol. Genet. Genomics 2001, 266:56-63.
43. Zeilinger S., Reithner B., Scala V., Peissl I., Lorito M., Mach R.L. Signal transduction by Tga3, a novel G protein alpha subunit of Trichoderma atroviride. Appl. Environ. Microbiol. 2005, 71:1591-1597.
44. Zhou Q., Xu J., Kou Y., Lv X., Zhang X., Zhao G., Zhang W., Chen G., Liu W. Differential involvement of β-glucosidases from Hypocrea jecorina in rapid induction of cellulase genes by cellulose and cellobiose. Eukaryot. Cell 2012, 11:1371-1381.
45. Znameroski E.A., Coradetti S.T., Roche C.M., Tsai J.C., Iavarone A.T., Cate J.H.D., Glass N.L. Induction of lignocellulose-degrading enzymes in Neurospora crassa by cellodextrins. Proc. Natl. Acad. Sci. USA 2012, 109:6012-6017.