Regulation of conidiation and adenylyl cyclase levels by the Gα protein GNA-3 in Neurospora crassa

Molecular and Cellular Biology

Volumn 20, Issue 20, 2000, Pages 7693-7705

  Kays, A M ^a   Rowley, P S ^a   Baasiri, R A ^a   Borkovich, K A ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; FUNGAL PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGUS GROWTH; GENE EXPRESSION REGULATION; GENE ISOLATION; MAGNAPORTHE GRISEA; NEUROSPORA CRASSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PODOSPORA ANSERINA; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; CLONING, MOLECULAR; CROSSES, GENETIC; CYCLIC AMP; FERTILITY; FUNGAL PROTEINS; GENE TARGETING; GENES, FUNGAL; GUANOSINE TRIPHOSPHATE; HETEROTRIMERIC GTP-BINDING PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; NEUROSPORA CRASSA; OSMOLAR CONCENTRATION; PHENOTYPE; QUINIC ACID; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, U.S. GOV'T, P.H.S.;

CRYPHONECTRIA PARASITICA; MAGNAPORTHE GRISEA; NEUROSPORA CRASSA; PODOSPORA ANSERINA;

EID: 0033806187     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.20.7693-7705.2000     Document Type: Article

References (85)

1. Divergent cAMP signaling pathways regulate growth and pathogenesis in the rice blast fungus Magnaporthe grisea
2. RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans
3. Cryptococcus neoformans mating and virulence are regulated by the G-protein a subunit GPA1 and cAMP
4. Kinetics of differentiation of conidiophores and conidia by colonies of Aspergillus nidulans
5. Overlapping functions for two G protein α subunits in Neurospora crassa
6. The HMG-1 box protein family: Classification and functional relationships
7. Receptor-to-effector signaling through G proteins: Roles for βγ dimers as well as α subunits
8. Sex and crime: Heterotrimeric G proteins in fungal mating and pathogenesis
9. cAMP signalling in pathogenic fungi: Control of dimorphic switching and pathogenicity
10. Signal transduction pathways and heterotrimeric G proteins
11. A simple and sensitive saturation assay method for the measurement of adenosine 3': 5'-cyclic monophosphate
12. Regulatory sequences involved in the translation of Neurospora crassa mRNA: Kozak sequences and stop codons
13. Loss of growth polarity and mislocalization of septa in a Neurospora mutant altered in the regulatory subunit of cAMP-dependent protein kinase
14. Use of gene replacement transformation to elucidate gene function in the qa gene cluster of Neurospora crassa
15. Extensive alteration of fungal gene transcript accumulation and elevation of G-protein-regulated cAMP levels by a virulence-attenuating hypovirus
16. Virus-mediated or transgenic suppression of a G-protein α subunit and attenuation of fungal virulence
17. Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae
18. Conidiation of Neurospora crassa in submerged culture without mycelial phase
19. Genetic and microbiological research techniques for Neurospora crassa
20. Visualizing signal transduction: Receptors, G-proteins, and adenylate cyclases
21. The yeast trimeric guanine nucleotide-binding protein α subunitm, Gpa2p, controls the meiosis-specific kinase Ime2p activity in response to nutrients
22. Identification of a cAMP-dependent protein kinase catalytic subunit required for virulence and morphogenesis in Ustilago maydis
23. Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein
24. Distinct roles for two G protein α subunits in fungal virulence, morphology, and reproduction revealed by targeted gene disruption
25. Use of PCR to quantitate relative differences in gene expression
26. DNA sequence, organization and regulation of the qa gene cluster of Neurospora crassa
27. cAMP regulates morphogenesis in the fangal pathogen Ustilago maydis
28. Microcycle conidiation induced by partial nitrogen deprivation in Neurospora crassa
29. The structure and organization of nuclear genes of filamentous fungi
30. Aspergillus sporulation and mycotoxin production both require inactivation of the FadA Gα protein-dependent signaling pathway
31. Characterization of a fission yeast gene, gpa2, that encodes a Gα subunit involved in the monitoring of nutrition
32. The Gα(i) homologue gna-1 controls multiple differentiation pathways in Neurospora crassa
33. Positive regulation of adenylyl cyclase activity by a Gα(i) homolog in Neurospora crassa
34. Identification of bdm-1, a gene involved in G protein β-subunit function and α-subunit accumulation
35. Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombe
36. Isolation and characterization of the adenylate cyclase structural gene of Neurospora crassa
37. A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition toi growth on glucose
38. Signaling via cAMP in fungi: Interconnections with mitogen-activated protein kinase pathways
39. Crosstalk between cAMP and pheromone signalling pathways in Ustilago maydis
40. Gpa2p, a G-protein α-subunit, regulates growth and pseudohyphal development in Saccharomyces cerevisiae via a cAMP-dependent mechanism
41. fluG and fluA function interdependently to initiate conidiophore development in Aspergillus nidulans through brlAβ activation
42. The HXT1 gene product of Saccharornyces cerevisiae is a new member of the family of hexose transporters
43. Fill, a G-protein α-subunit that acts up-stream of cAMP and is essential for dimorphic switching in haploid cells of Ustilago hordei
44. G protein α subunit genes control growth, development, and pathogenicity of Magnaporthe grisea
45. Yeast pseudohyphal growth is regulated by GPA2, a G protein α homolog
46. The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae
47. The G protein-coupled receptor Gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae
48. An additional copy of the adenylate cyclase-encoding gene relieves developmental defects produced by a mutation in a vegetative incompatibility-controlling gene in Podospora anserina
49. MOD-D, a Gα subunit of the fungus Podospora anserina, is involved in both regulation of development and vegetative incompatibility
50. rco-3, a gene involved in glucose transport and conidiation in Neurospora crassa
51. Adenylyl cyclase is dispensable for vegetative cell growth in the fission yeast Schizo-saccharomyces pombe
52. Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase
53. Identification of the structural gene and nonsense alleles for adenylate cyclase in Saccharomyces cerevisiae
54. A suppressor mutation which suppresses adenylyl cyclase mutations in Neurospora crassa
55. Expressed sequence from conidial, mycelial and sexual stages of Neurospora crassa
56. Glucose repression of fbp1 transcription in Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein α subunit encoded by gpa2 (git8)
57. Photoreception in Neurospora crassa: Correlation of reduced light sensitivity with flavin deficiency
58. The use of Ignite (Fasta; glufosinate; phosphinothricin) to select transformants of bar containing lasmids in Neurospora crassa
59. New plasmid and λ/plasmid hybrid vectors and a Neurospora crassa genomic library containing the bar selectable marker and the Cre/lox site-specific recombination system for use in filamentous fungi
60. Cyclic AMP-dependent protein kinase regulates pseudophyphal differentiation in Saccharomyces cerevisiae
61. Paedogenetic conidiation in Neurospora crassa
62. Signal transduction by MAP kinase cascades in budding yeast
63. G proteins in Ustilago maydis: Transmission of multiple signals?
64. Molecular analysis of a Neurospora crassa gene expressed during conidiation
65. The three yeast A kinases have specific signaling functions in pseudohyphal growth
66. Reconstitution of adenylate cyclase in Neurospora from two components of the enzyme
67. 2+-dependent guanine nucleotide-stimulated adenylate cyclase from Neurospora crassa
68. Developmental expression of genes involved iniconidiation and amino acid biosynthesis in Neurospora crassa
69. Detection and analysis of proteins expressed from cloned genes
70. Starvation stress modulates the expression of the Aspergillus nidulans brlA regulatory gene
71. Genetic control of fungal differentiation: The three sporulation pathways of Neurospora crassa
72. Use of a bacterial hygromycin B resistance gene as a dominant selectable marker in Neurospora crassa transformation
73. A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
74. The control of Neurospora crassa morphology by cyclic adenosine 3',5'-monophosphate and dibutyryl cyclic adenosine 3',5'-monophosphate
75. Surface receptor-mediated activation of adenylate cyclase in Dictyostelium
76. Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae
77. Ultrastructural study of microcyclic macroconidiation in Neurospora crassa
78. Detection and quantitation of RNA transcribed from bacterial chromosomes and plasmids
79. Identification of a G protein α subunit from Neurospora crassa that is a member of the G(i) family
80. Electroporation-based transformation of freshly harvested conidia ofNeurospora crassa
81. Analysis of the function of the 70-kilodalton cyclase-associated protein (CAP) by using mutants of adenylyl cyclase defective in CAP binding
82. G-protein-coupled receptors: Molecular mechanisms involved in receptor activation and selectivity of G-protein recognition
83. GPR1 encodes a putative G protein-coUpled receptor that associates with the Gpa2p Gα subunit and functions in a Ras-independent pathway
84. The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development
85. G-protein coupled receptor from yeast Saccharomyces cerevisiae