Microparticles during sepsis: Target, canary or cure?

Intensive Care Medicine

Volumn 39, Issue 10, 2013, Pages 1854-1856

  Zafrani, Lara ^a   Ince, Can ^b   Yuen, Peter S T ^c  

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; COMPLEMENT COMPONENT C5B; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCOPROTEIN; INTERLEUKIN 6; PHOSPHATIDYLSERINE; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR;

DEEP VEIN THROMBOSIS; DISSEMINATED INTRAVASCULAR CLOTTING; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; LEUKOCYTE; MEMBRANE MICROPARTICLE; MEMBRANE VESICLE; MENINGOCOCCEMIA; NONHUMAN; PATHOGENICITY; PROTEOMICS; REVIEW; SEPSIS; SEPTIC SHOCK; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOTIC THROMBOCYTOPENIC PURPURA; TISSUE INJURY;

CELL-DERIVED MICROPARTICLES; DISSEMINATED INTRAVASCULAR COAGULATION; FEMALE; HUMANS; MALE; MULTIPLE ORGAN FAILURE; SHOCK, SEPTIC;

EID: 84884589589     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-013-3047-0     Document Type: Review

References (13)

1. Delabranche X, Boisrame Helms J, Asfar P, Berger A, Mootien Y, Lavigne T, Grunebaum L, Lanza F, Gachet C, Freyssinet JM, Toti F, Meziani F (2013) Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy. Intensive Care Med
2. Morel O, Toti F, Hugel B, Bakouboula B, Camoin-Jau L, Dignat-George F, Freyssinet JM (2006) Procoagulant microparticles: disrupting the vascular homeostasis equation? Arterioscler Thromb Vasc Biol 26:2594-2604
3. Eyre J, Burton JO, Saleem MA, Mathieson PW, Topham PS, Brunskill NJ (2011) Monocyte and endothelial-derived microparticles induce an inflammatory phenotype in human podocytes. Nephron Exp Nephrol 119:58-66
4. Mostefai HA, Meziani F, Mastronardi ML, Agouni A, Heymes C, Sargentini C, Asfar P, Martinez MC, Andriantsitohaina R (2008) Circulating microparticles from patients with septic shock exert protective role in vascular function. Am J Respir Crit Care Med 178:1148-1155
5. Ogura H, Tanaka H, Koh T, Fujita K, Fujimi S, Nakamori Y, Hosotsubo H, Kuwagata Y, Shimazu T, Sugimoto H (2004) Enhanced production of endothelial microparticles with increased binding to leukocytes in patients with severe systemic inflammatory response syndrome. J Trauma 56:823-830 discussion 830-821
6. Nieuwland R, Berckmans RJ, McGregor S, Boing AN, Romijn FP, Westendorp RG, Hack CE, Sturk A (2000) Cellular origin and procoagulant properties of microparticles in meningococcal sepsis. Blood 95:930-935
7. Zafrani L, Gerotziafas G, Byrnes C, Hu X, Perez J, Levi C, Placier S, Letavernier E, Leelahavanichkul A, Haymann JP, Elalamy I, Miller JL, Star RA, Yuen PS, Baud L (2012) Calpastatin controls polymicrobial sepsis by limiting procoagulant microparticle release. Am J Respir Crit Care Med 185:744-755
8. Wang JG, Manly D, Kirchhofer D, Pawlinski R, Mackman N (2009) Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice. J Thromb Haemost 7:1092-1098
9. Freyssinet JM, Toti F (2010) Formation of procoagulant microparticles and properties. Thromb Res 125(Suppl 1):S46-S48
10. Myers D Jr, Farris D, Hawley A, Wrobleski S, Chapman A, Stoolman L, Knibbs R, Strieter R, Wakefield T (2002) Selectins influence thrombosis in a mouse model of experimental deep venous thrombosis. J Surg Res 108:212-221
11. Jimenez JJ, Jy W, Mauro LM, Horstman LL, Soderland C, Ahn YS (2003) Endothelial microparticles released in thrombotic thrombocytopenic purpura express von Willebrand factor and markers of endothelial activation. Br J Haematol 123:896-902
12. Hamilton KK, Hattori R, Esmon CT, Sims PJ (1990) Complement proteins C5b-9 induce vesiculation of the endothelial plasma membrane and expose catalytic surface for assembly of the prothrombinase enzyme complex. J Biol Chem 265:3809-3814
13. Densmore JC, Signorino PR, Ou J, Hatoum OA, Rowe JJ, Shi Y, Kaul S, Jones DW, Sabina RE, Pritchard KA Jr, Guice KS, Oldham KT (2006) Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. Shock 26:464-471