Circulating microparticles from patients with septic shock exert protective role in vascular function

American Journal of Respiratory and Critical Care Medicine

Volumn 178, Issue 11, 2008, Pages 1148-1155

  Mostefai, Hadj Ahmed ^a   Meziani, Ferhat ^a,b   Mastronardi, Maria Letizia ^a   Agouni, Abdelali ^a   Heymes, Christophe ^c   Sargentini, Cyrille ^b   Asfar, Pierre ^b   Martinez, Maria Carmen ^a   Andriantsitohaina, Ramaroson ^a,d  

^a UNIVERSITÉ D'ANGERS   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c INSERM   (France)

^d Universite d'Angers   (France)

Author keywords

Cyclooxygenase; Microvesicles; Oxidative stress; Sepsis; Vasomotricity

Indexed keywords

7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; CALCIUM; CALCIUM CHANNEL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; LIPOPOLYSACCHARIDE; NITRIC OXIDE; RHO KINASE; RHO KINASE INHIBITOR; SEROTONIN; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL FUNCTION; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIAL MICROPARTICLE; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; HEART PROTECTION; HUMAN; MALE; MOUSE; NONHUMAN; PLATELET MICROPARTICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPTIC SHOCK; VASCULAR RING;

EID: 56749178349     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200712-1835OC     Document Type: Article

References (26)

1. Balk RA. Severe sepsis and septic shock. Crit Care Clin 2000;16:179-192.
2. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G; SCCM/ESICM/ACCP/ ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-1256.
3. Galley HF, Webster NR. The immunoinflammatory cascade. Br J Anaesth 1996;77:11-16.
4. Martínez MC, Tesse A, Zobairi F, Andriantsitohaina R. Shed membrane microparticles from circulating and vascular cells in regulating vascular function. Am J Physiol 2005;288:H1004-H1009.
5. Hugel B, Martinez MC, Kunzelmann C, Freyssinet JM. Membrane microparticles: two sides of the coin. Physiology (Bethesda) 2005;20:22-27.
6. Nieuwland R, Berckmans RJ, McGregor S, Böing AN, Romijn FP, Westendorp RG, Hack CE, Sturk A. Cellular origin and procoagulant properties of microparticles in meningococcal sepsis. Blood 2000;95:930-935.
7. Aras O, Shet A, Bach RR, Hysjulien JL, Slungaard A, Hebbel RP, Escolar G, Jilma B, Key NS. Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia. Blood 2004;103:4545-4553.
8. Soriano AO, Wenche J, Chirinos JA, Valdivia MA, Velasquez HS, Jimenez JJ, Horstman LL, Kett DH, Schein RM, Ahn YS. Levels of endothelial and platelet microparticles and their interactions with leukocytes negatively correlate with organ dysfunction and predict mortality in severe sepsis. Crit Care Med 2005;33:2540-2546.
9. Assreuy J. Nitric oxide and cardiovascular dysfunction in sepsis. Endocr Metab Immune Disord Drug Targets 2006;6:165-173.
10. Stoclet JC, Martinez MC, Ohlmann P, Chasserot S, Schott C, Kleschyov AL, Schneider F, Andriantsitohaina R. Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock. Circulation 1999;100:107-112.
11. American College of Chest Physicians, Society of Critical Care Medicine. Consensus conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20:864-874.
12. Martínez MC, Larbret F, Zobairi F, Coulombe J, Debili N, Vainchenker W, Ruat M, Freyssinet JM. Transfer of differentiation signal by membrane microvesicles harboring Hedgehog morphogens. Blood 2006;108:3012-3020.
13. Amabile N, Guerin AP, Leroyer A, Mallat Z, Nguyen C, Boddaert J, London GM, Tedgui A, Boulanger CM. Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure. J Am Soc Nephrol 2005;16:3381-3388.
14. Meziani F, Tesse A, David E, Martinez MC, Wangesteen R, Schneider F, Andriantsitohaina R. Shed membrane particles from preeclamptic women generate vascular wall inflammation and blunt vascular contractility. Am J Pathol 2006;169:1473-1483.
15. Tesse A, Martinez MC, Hugel B, Chalupsky K, Muller CD, Meziani F, Mitolo-Chieppa D, Freyssinet JM, Andriantsitohaina R. Upregulation of pro-inflammatory proteins through NF-κB pathway by shed membrane microparticles results in vascular hyporeactivity. Arterioscler Thromb Vasc Biol 2005;25:2522-2527.
16. Martin S, Tesse A, Hugel B, Martinez MC, Morel O, Freyssinet JM, Andriantsitohaina R. Shed membrane particles from T lymphocytes impair endothelial function and regulate endothelial protein expression. Circulation 2004;109:1653-1659.
17. Khoo JP, Alp NJ, Bendall JK, Kawashima S, Yokoyama M, Zhang YH, Casadei B, Channon KM. EPR quantification of vascular nitric oxide production in genetically modified mouse models. Nitric Oxide 2004;10:156-161.
18. Piper RD, Pitt-Hyde ML, Anderson LA, Sibbald WJ, Potter RF. Leukocyte activation and flow behavior in rat skeletal muscle in sepsis. Am J Respir Crit Care Med 1998;157:129-134.
19. 2+ release and entry during contraction elicited by norepinephrine in rat resistance arteries. Am J Physiol 1999;276:H300-H308.
20. Martinez MC, Randriamboavonjy V, Ohlmann P, Komas N, Duarte J, Schneider F, Stoclet JC, Andriantsitohaina R. Involvement of protein kinase C, tyrosine kinases, and Rho kinase in Ca2+ handling of human small arteries. Am J Physiol Heart Circ Physiol 2000;279:H1228-H1238.
21. Martínez MC, Muller B, Stoclet JC, Andrihantsitohaina R. Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery. Br J Pharmacol 1996;118:1218-1222.
22. Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 2000;86:494-501.
23. phox homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ Res 2001;88:888-894.
24. Salvemini D, Cuzzocrea S. Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine. Crit Care Med 2003;31:S29-S38.
25. Martyn KD, Frederick LM, von Loehneysen K, Dinauer MC, Knaus UG. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal 2006;18:69-82.
26. i in pulmonary artery smooth muscle cells. Biochem Biophys Res Commun 2006;351:784-790.