Evaluation of the toxicity forecasting capability of epa's toxcast phase i data: Can toxcast in vitro assays predict carcinogenicity?

Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews

Volumn 31, Issue 3, 2013, Pages 201-212

  Benigni, Romualdo ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

alternative testing; cancer; high throughput screening; prediction; regulation; ToxCast

Indexed keywords

CANCER; FORECASTING CAPABILITY; GENOTOXICITY TESTING; HIGH-THROUGHPUT SCREENING; IN-VITRO ASSAYS; NONGENOTOXIC CARCINOGENS; REGULATION; TOXCAST;

CARCINOGENS; TOXIC MATERIALS;

FORECASTING;

CARCINOGEN; ESTROGEN RECEPTOR; PESTICIDE;

ARTICLE; BIOASSAY; CARCINOGENICITY; CELL INTERACTION; CLUSTER ANALYSIS; FALSE POSITIVE RESULT; FORECASTING; GENOTOXICITY; GOLD STANDARD; IN VITRO STUDY; METABOLIC ACTIVATION; NONHUMAN; RISK ASSESSMENT; STRUCTURE ACTIVITY RELATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MICE; RATS; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

EID: 84884582909     PISSN: 10590501     EISSN: 15324095     Source Type: Journal    
DOI: 10.1080/10590501.2013.824188     Document Type: Article

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