Anodal transcranial direct current stimulation transiently improves contrast sensitivity and normalizes visual cortex activation in individuals with amblyopia

Neurorehabilitation and Neural Repair

Volumn 27, Issue 8, 2013, Pages 760-769

  Spiegel, Daniel P ^a   Byblow, Winston D ^a   Hess, Robert F ^b   Thompson, Benjamin ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

contrast sensitivity; functional magnetic resonance imaging (fMRI); neuroplasticity

Indexed keywords

ADULT; AGED; AMBLYOPIA; ARTICLE; CLINICAL ARTICLE; CONTRAST SENSITIVITY; CONTROLLED STUDY; ELECTRODE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; NERVE POTENTIAL; OXYGEN BLOOD LEVEL; TRANSCRANIAL DIRECT CURRENT STIMULATION; TREATMENT RESISTANT DEPRESSION; VISION; VISUAL CORTEX;

CONTRAST SENSITIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI); NEUROPLASTICITY;

ADULT; AGED; AMBLYOPIA; CONTRAST SENSITIVITY; FEMALE; HUMANS; MALE; MIDDLE AGED; TRANSCRANIAL MAGNETIC STIMULATION; VISUAL CORTEX; YOUNG ADULT;

EID: 84884579603     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968313491006     Document Type: Article

References (54)

1. Robaei D, Rose KA, Ojaimi E, Kifley A, Martin FJ, Mitchell P. Causes and associations of amblyopia in a population-based sample of 6-year-old Australian children. Arch Ophthalmol. 2006 ; 124: 878-884
2. Hess RF, Howell ER. The threshold contrast sensitivity function in strabismic amblyopia: evidence for a two type classification. Vision Res. 1977 ; 17: 1049-1055
3. Li J, Thompson B, Ding Z, et al. Does partial occlusion promote normal binocular function?. Invest Ophthalmol Vis Sci. 2012 ; 53: 6818-6827
4. Astle AT, Webb BS, McGraw PV. Can perceptual learning be used to treat amblyopia beyond the critical period of visual development?. Ophthalmic Physiol Opt. 2011 ; 31: 564-573
5. Jampolsky A. Characteristics of suppression in strabismus. AMA Arch Ophthalmol. 1955 ; 54: 683-696
6. Li J, Thompson B, Lam CS, et al. The role of suppression in amblyopia. Invest Ophthalmol Vis Sci. 2011 ; 52: 4169-4176
7. Thompson B, Mansouri B, Koski L, Hess RF. From motor cortex to visual cortex: the application of noninvasive brain stimulation to amblyopia. Dev Psychobiol. 2012 ; 54: 263-273
8. Sengpiel F, Blakemore C, Kind PC, Harrad R. Interocular suppression in the visual cortex of strabismic cats. J Neurosci. 1994 ; 14: 6855-6871
9. Moschos MM, Margetis I, Tsapakis S, Panagakis G, Chatzistephanou IK, Iliakis E. Multifocal visual evoked potentials in amblyopia due to anisometropia. Clin Ophthalmol. 2010 ; 4: 849-853
10. Hess RF, Li X, Lu G, Thompson B, Hansen BC. The contrast dependence of the cortical fMRI deficit in amblyopia: a selective loss at higher contrasts. Hum Brain Mapp. 2010 ; 31: 1233-1248
11. Conner IP, Odom JV, Schwartz TL, Mendola JD. Monocular activation of V1 and V2 in amblyopic adults measured with functional magnetic resonance imaging. J AAPOS. 2007 ; 11: 341-350
12. Barnes GR, Hess RF, Dumoulin SO, Achtman RL, Pike GB. The cortical deficit in humans with strabismic amblyopia. J Physiol. 2001 ; 533 (pt 1). 281-297
13. Farivar R, Thompson B, Mansouri B, Hess RF. Interocular suppression in strabismic amblyopia results in an attenuated and delayed hemodynamic response function in early visual cortex. J Vis. 2011 ; 11 (14). 16
14. Sengpiel F, Jirmann KU, Vorobyov V, Eysel UT. Strabismic suppression is mediated by inhibitory interactions in the primary visual cortex. Cereb Cortex. 2006 ; 16: 1750-1758
15. Mower GD, Christen WG, Burchfiel JL, Duffy FH. Microiontophoretic bicuculline restores binocular responses to visual cortical neurons in strabismic cats. Brain Res. 1984 ; 309: 168-172
16. Nitsche MA, Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol. 2000 ; 527 (pt 3). 633-639
17. Nitsche MA, Cohen LG, Wassermann EM, et al. Transcranial direct current stimulation: state of the art 2008. Brain Stimul. 2008 ; 1: 206-223
18. Antal A, Nitsche MA, Paulus W. External modulation of visual perception in humans. Neuroreport. 2001 ; 12: 3553-3555
19. Antal A, Kincses TZ, Nitsche MA, Paulus W. Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Exp Brain Res. 2003 ; 150: 375-378
20. Antal A, Kincses TZ, Nitsche MA, Bartfai O, Paulus W. Excitability changes induced in the human primary visual cortex by transcranial direct current stimulation: direct electrophysiological evidence. Invest Ophthalmol Vis Sci. 2004 ; 45: 702-707
21. Antal A, Nitsche MA, Paulus W. Transcranial direct current stimulation and the visual cortex. Brain Res Bull. 2006 ; 68: 459-463
22. Stagg CJ, Best JG, Stephenson MC, et al. Polarity-sensitive modulation of cortical neurotransmitters by transcranial stimulation. J Neurosci. 2009 ; 29: 5202-5206
23. Stagg CJ, Bachtiar V, Johansen-Berg H. The role of GABA in human motor learning. Curr Biol. 2011 ; 21: 480-484
24. Stagg CJ, Jayaram G, Pastor D, Kincses ZT, Matthews PM, Johansen-Berg H. Polarity and timing-dependent effects of transcranial direct current stimulation in explicit motor learning. Neuropsychologia. 2011 ; 49: 800-804
25. Spiegel DP, Hansen BC, Byblow WD, Thompson B. Anodal transcranial direct current stimulation reduces psychophysically measured surround suppression in the human visual cortex. PLoS One. 2012 ; 7: e36220
26. Beaudot WHA. Psykinematix: a new psychophysical tool for investigation visual impairment due to neural dysfunctions. Vision. 2009 ; 21: 19-32
27. Leek MR. Adaptive procedures in psychophysical research. Percept Psychophys. 2001 ; 63: 1279-1292
28. Thompson B, Mansouri B, Koski L, Hess RF. Brain plasticity in the adult: modulation of function in amblyopia with rTMS. Curr Biol. 2008 ; 18: 1067-1071
29. Li X, Dumoulin SO, Mansouri B, Hess RF. The fidelity of the cortical retinotopic map in human amblyopia. Eur J Neurosci. 2007 ; 25: 1265-1277
30. Nitsche MA, Doemkes S, Karaköse T, et al. Shaping the effects of transcranial direct current stimulation of the human motor cortex. J Neurophysiol. 2007 ; 97: 3109-3117
31. Kraft A, Roehmel J, Olma MC, Schmidt S, Irlbacher K, Brandt SA. Transcranial direct current stimulation affects visual perception measured by threshold perimetry. Exp Brain Res. 2010 ; 207: 283-290
32. Gandiga PC, Hummel FC, Cohen LG. Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin Neurophysiol. 2006 ; 117: 845-850
33. Vanneste S, Focquaert F, Van De Heyning P, De Ridder D. Different resting state brain activity and functional connectivity in patients who respond and not respond to bifrontal tDCS for tinnitus suppression. Exp Brain Res. 2011 ; 210: 217-227
34. Vanneste S, Plazier M, Ost J, van der Loo E, Van de Heyning P, De Ridder D. Bilateral dorsolateral prefrontal cortex modulation for tinnitus by transcranial direct current stimulation: a preliminary clinical study. Exp Brain Res. 2010 ; 202: 779-785
35. Bradnam LV, Stinear CM, Barber PA, Byblow WD. Contralesional hemisphere control of the proximal paretic upper limb following stroke. Cereb Cortex. 2012 ; 22: 2662-2671
36. Talairach J, Tournoux P Coplanar Stereotaxic Atlas of the Human Brain. New York, NY: Thieme ; 1987 :
37. Wandell BA, Dumoulin SO, Brewer AA. Visual field maps in human cortex. Neuron. 2007 ; 56: 366-383
38. Hess RF, Thompson B, Gole G, Mullen KT. Deficient responses from the lateral geniculate nucleus in humans with amblyopia. Eur J Neurosci. 2009 ; 29: 1064-1070
39. Fritsch B, Reis J, Martinowich K, et al. Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron. 2010 ; 66: 198-204
40. Datta A, Bansal V, Diaz J, Patel J, Reato D, Bikson M. Gyri-precise head model of transcranial direct current stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad. Brain Stimul. 2009 ; 2: 201 207.e1-207
41. Wagner T, Fregni F, Fecteau S, Grodzinsky A, Zahn M, Pascual-Leone A. Transcranial direct current stimulation: a computer-based human model study. Neuroimage. 2007 ; 35: 1113-1124
42. Halko MA, Datta A, Plow EB, Scaturro J, Bikson M, Merabet LB. Neuroplastic changes following rehabilitative training correlate with regional electrical field induced with tDCS. Neuroimage. 2011 ; 57: 885-891
43. Levi DM. Visual processing in amblyopia: human studies. Strabismus. 2006 ; 14: 11-19
44. Bi H, Zhang B, Tao X, Harwerth RS, Smith EL 3rd, Chino YM. Neuronal responses in visual area V2 (V2) of macaque monkeys with strabismic amblyopia. Cereb Cortex. 2011 ; 21: 2033-2045
45. Muckli L, Kiess S, Tonhausen N, Singer W, Goebel R, Sireteanu R. Cerebral correlates of impaired grating perception in individual, psychophysically assessed human amblyopes. Vision Res. 2006 ; 46: 506-526
46. Antal A, Polania R, Schmidt-Samoa C, Dechent P, Paulus W. Transcranial direct current stimulation over the primary motor cortex during fMRI. Neuroimage. 2011 ; 55: 590-596
47. Antal A, Kovács G, Chaieb L, Cziraki C, Paulus W, Greenlee MW. Cathodal stimulation of human MT+ leads to elevated fMRI signal: a tDCS-fMRI study. Restor Neurol Neurosci. 2012 ; 30: 255-263
48. Accornero N, Li Voti P, La Riccia M, Gregori B. Visual evoked potentials modulation during direct current cortical polarization. Exp Brain Res. 2007 ; 178: 261-266
49. Iyer MB, Schleper N, Wassermann EM. Priming stimulation enhances the depressant effect of low-frequency repetitive transcranial magnetic stimulation. J Neurosci. 2003 ; 23: 10867-10872
50. Ridding MC, Rothwell JC. Is there a future for therapeutic use of transcranial magnetic stimulation?. Nat Rev Neurosci. 2007 ; 8: 559-567
51. Silvanto J, Pascual-Leone A. State-dependency of transcranial magnetic stimulation. Brain Topogr. 2008 ; 21: 1-10
52. Thickbroom G. Transcranial magnetic stimulation and synaptic plasticity: experimental framework and human models. Exp Brain Res. 2007 ; 180: 583-593
53. Sengpiel F, Blakemore C. The neural basis of suppression and amblyopia in strabismus. Eye. 1996 ; 10: 250-258
54. Plow EB, Obretenova SN, Fregni F, Pascual-Leone A, Merabet LB. Comparison of visual field training for hemianopia with active versus sham transcranial direct cortical stimulation. Neurorehabil Neural Repair. 2012 ; 26: 616-626