Biology-guided adaptive radiotherapy (BiGART)-more than a vision?

Acta Oncologica

Volumn 52, Issue 7, 2013, Pages 1243-1247

  Grau, Cai ^a   Hoyer, Morten ^a   Alber, Markus ^a   Overgaard, Jens ^a   Lindegaard, Jacob Christian ^a   Muren, Ludvig Paul ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY GUIDED ADAPTIVE RADIOTHERAPY; CANCER RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DIFFUSION WEIGHTED IMAGING; DOSIMETRY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOBIOLOGY; REVIEW; CANCER MORPHOLOGY; CANCER RESISTANCE; CELL DENSITY; CELL PROLIFERATION; CLINICAL DECISION MAKING; CYTOPATHOLOGY; EDITORIAL; GENETIC ANALYSIS; GENOMICS; HYPOXIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SELECTION; RADIATION DOSE; RADIATION RESPONSE; RADIOSENSITIVITY; TREATMENT PLANNING;

ADAPTATION, BIOLOGICAL; BIOLOGY; HUMANS; NEOPLASMS; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, IMAGE-GUIDED;

EID: 84884578658     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2013.829245     Document Type: Review

References (63)

1. Grau C, Hoyer M, Lindegaard J, Overgaard J. The emerging evidence for stereotactic body radiotherapy. Acta Oncol 2006;45:771-4
2. Grau C, Muren L P, Hoyer M, Lindegaard J, Overgaard J. Image-guided adaptive radiotherapy-integration of biology and technology to improve clinicaLoutcome. Acta Oncol 2008;47:1182-5
3. Muren LP, Petersen JB, Hansen J, Hafslund R. M edical physics in the Nordic countries: The past, the present and the future. Acta Oncol 2009;48:165-8
4. Grau C, Olsen D R, Overgaard J, Hoyer M, Lindegaard J C, Muren LP. Biology-guided adaptive radiation therapy-presence or future? Acta Oncol 2010;49:884-7
5. Muren LP, Rossi C, Hug E, Lee A, Glimelius B. E stablishing anDexpanding the indications for proton and particle therapy. Acta Oncol 2013;52:459-62
6. Winther M. Hypoxia-regulated gene expression and prognosis in loco-regional gastroesophageal cancer. Acta Oncol 2013;(this issue
7. I shkanian A S, Zafarana G, Thoms J, Bristow RG. A rray CGHas a potential predictor of radiocurability in intermediate risk prostate cancer. Acta Oncol 2010;49:888-94
8. Toustrup K, Sorensen BS, Lassen P, Wiuf C, Alsner J, Overgaard J, et al. Gene expression classifi er predicts for hypoxic modifi cation of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck. Radiother Oncol 2012;102:122-9
9. Busk M. PET imaging of tumor hypoxia using 18F labeled pimonidazole. Acta Oncol 2013;(this issue
10. Malinen E. F unctionaLimaging to monitor vascular and metabolic response in canine head and neck tumors during fractionated radiotherapy. Acta Oncol 2013;(this issue
11. Nielsen T. U ltra-high fi eld 1 H magnetic resonance imaging approaches for acute hypoxia. Acta Oncol 2013;(this issue
12. Partridge M, Yamamoto T, Grau C, Hoyer M, Muren LP. Imaging of normal lung, liver and parotid gland function for radiotherapy. Acta Oncol 2010;49:997-1011
13. Mortensen L S, Johansen J, Kallehauge J, Primdahl H, Busk M, Lassen P, et al. FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial. Radiother Oncol 2012;105:14-20
14. Ardenkjaer-Larsen J H. M agnetic resonance imaging of tumor oxygenation and metabolic profi le. Acta Oncol 2013;(this issue
15. Thor M, Petersen JB, Bentzen L, Hoyer M, Muren LP. Deformable image registration for contour propagation from CT to cone-beam CT scans in radiotherapy of prostate cancer . Acta Oncol 2011;50:918-25
16. Malinen E, Rodal J, Knudtsen IS, Sovik A, Skogmo H.K. Spatiotemporal analysis of tumor uptake patterns in dynamic (18)FDG-PET and dynamic contrast enhanced CT. Acta Oncol 2011;50:873-82
17. Munck Af Rosenschold P, Engelholm S, Ohlhues L, Law I, Vogelius I, Engelholm SA. Photon and proton therapy planning comparison for malignant glioma based on CT, FDG-PET, DTI-MRI and fi ber tracking. Acta Oncol 2011;50:777-83
18. Andersen E KF, Kristensen GB, Lyng HD, Malinen E. Pharmacokinetic analysis and k-means clustering of DCEMR images for radiotherapy outcome prediction of advanced cervical cancers. Acta Oncol 2011;50:859-65
19. Maggio A, Fiorino C, Mangili P, Cozzarini C, De Cobelli F, Cattaneo GM, et al. Feasibility of safe ultra-high (EQD(2) >100 Gy) dose escalation on dominant intra-prostatic lesions (DILs) by helical tomotherapy. Acta Oncol 2011;50:25-34
20. Toma-Dasu I, Uhrdin J, Antonovic L, Dasu A, Nuyts S, Dirix P, et al. Dose prescription and treatment planning based on FMISO-PET hypoxia. Acta Oncol 2012;51:222-30
21. Nyeng TB, Kallehauge JF, Hoyer M, Petersen JB, Poulsen PR, Muren LP. Clinical validation of a 4D-CT based method for lung ventilation measurement in phantoms and patients. Acta Oncol 2011;50:897-907
22. Palma DA, De Koste JRV, Verbakel W, Senan S. A new approach to quantifying lung damage after stereotactic body radiation therapy. Acta Oncol 2011;50:509-17
23. De Ruysscher D SH, Defraene G, Kerns S L, Christiaens M, De Ruyck K. Quantifi cation of radiation-induced lung damage with CT scans: The possible benefi t for radiogenomics Acta Oncol 2013;(this issue
24. Huang EX, Hope A J, Lindsay PE, Trovo M, El Naqa I, Deasy JO, et al. Heart irradiation as a risk factor for radiation pneumonitis. Acta Oncol 2011;50:51-60
25. Vogelius IR, Westerly DC, Aznar MC, CannoNgM, Korreman SS, Mackie TR, et al. Estimated radiation pneumonitis risk after photon versus proton therapy alone or combined with chemotherapy for lung cancer. Acta Oncol 2011;50:772-6
26. Knudtsen I S, Rodal J, Brustugun O T, Helland A, Skretting A, Malinen E. Dynamic respiratory gated (18)FDG-PET of lung tumors-Afeasibility study. Acta Oncol 2011;50:889-96
27. Andersen ES, Muren LP, Sorensen TS, Noe KO, Thor M, Petersen JB, et al. Bladder dose accumulation based on a biomechanical deformable image registration algorithm in volumetric modulated arc therapy for prostate cancer. Phys Med Biol 2012;57:7089-100
28. Thor M, Bentzen L, Hysing L B, Ekanger C, Helle S I, Karlsdottir A, et al. Prediction of rectum and bladder morbidity following radiotherapy of prostate cancer based on motion-inclusive dose distributions. Radiother Oncol 2013;107:147-52
29. Fellin F, Azzeroni R, Maggio A, Lorentini S, Cozzarini C, DImuziOn, et al. Helical tomotherapy anDintensity modulated proton therapy in the treatment of dominant intraprostatic lesion: A treatment planning comparison. Radiother Oncol 2013;107:207-12
30. Moller DS, Khalil A A, KnaPMM, Muren LP, Hoffmann L. A planning study of radiotherapy dose escalation of PETactive tumour volumes in non-small cell lung cancer patients. Acta Oncol 2011;50:883-8
31. Maggiulli E, Fiorino C, Passoni P, Broggi S, Gianolini S, Salvetti C, et al. Characterisation of rectal motion during neo-adjuvant radiochemotherapy for rectal cancer with image-guided tomotherapy: Implications for adaptive dose escalation strategies. Acta Oncol 2012;51:318-24
32. Fledelius W, Keall PJ, Cho BC, Yang XH, Morf D, Scheib S, et al. Tracking latency in image-based dynamic MLC tracking with direct image access. Acta Oncol 2011;50:952-9
33. Ravkilde T, Keall P J, Hojbjerre K, Fledelius W, Worm E, Poulsen PR. Geometric accuracy of dynamic MLC tracking witHan implantable wireDelectromagnetic transponder. Acta Oncol 2011;50:944-51
34. Skyt P S, Petersen J BB, Yates E S, Poulsen P R, Ravkilde T L, Balling P, Muren LP, et al. Dosimetric verifi cation 1 of complex radiotherapy witHa 3D optically based dosimetry system: Dose painting and target tracking. Acta Oncol 2013;(this issue
35. Nystrom H, Blomqvist E, Hoyer M, Montelius A, Muren LP, Nilsson P, et al. Particle therapy-a next logical step in the improvement of radiotherapy. Acta Oncol 2011;50:741-4
36. Schippers J M, Lomax AJ. E merging technologies in proton therapy. Acta Oncol 2011;50:838-50
37. Liao Z, Lin SH, Cox JD. S tatus of particle therapy for lung cancer. Acta Oncol 2011;50:745-56
38. Mendenhall N P, Malyapa R S, S u Z, Yeung D, Mendenhall WM, Li ZF. Proton therapy for head and neck cancer: Rationale, potentiaLindications, practical considerations, and current clinicaLevidence. Acta Oncol 2011;50:763-71
39. Thornqvist S, Muren LP, Bentzen L, Hysing LB, Hoyer M, Grau C, et al. Degradation of target coverage due to interfraction motion during intensity-modulated proton therapy of prostate anDelective targets. Acta Oncol 2013;52:521-7
40. Combs S. P roton and carbon ion radiotherapy for primary brain tumors and tumors of the skull base. Acta Oncol 2013;(this issue
41. Combs S. T reatment with heavy charged particles: Systematic review of results of clinical data and current clinical (comparative) trials. Acta Oncol 2013;(this issue
42. Schwartz DL, Garden A S, Shah SJ, Chronowski G, Sejpal S, Rosenthal DI, et al. Adaptive radiotherapy for head and neck cancer-Dosimetric results from a prospective clinical trial. Radiother Oncol 2013;106:80-4
43. Meijer GJ, Van Der Toorn PP, Bal M, Schuring D, Weterings J, de Wildt M. High precision bladder cancer irradiation by integrating Alibrary planning procedure of 6 prospectively generated SIB IMRT plans with image guidance using lipiodol markers. Radiother Oncol 2012;105:174-9
44. Nijkamp J, Marijnen C, van Herk M, van Triest B, Sonke JJ. Adaptive radiotherapy for long course neo-adjuvant treatment of rectal cancer. Radiother Oncol 2012;103:353-9
45. Madani I, Duprez F, Boterberg T, Van de Wiele C, Bonte K, Deron P, et al. Maximum tolerated dose in a phase I triaLon adaptive dose painting by numbers for head and neck cancer. Radiother Oncol 2011;101:351-5
46. Castadot P, Geets X, Lee JA, Gregoire V. A daptive functionaLimage-guideDiMRT in pharyngo-laryngeal squamous cell carcinoma: Is the gain in dose distribution worth the effort? Radiother Oncol 2011;101:343-50
47. Simone CB, 2nd, L y D, Dan T D, Ondos J, Ning H, Belard A, et al. Comparison of intensity-modulated radiotherapy, adaptive radiotherapy, proton radiotherapy, and adaptive proton radiotherapy for treatment of locally advanced head and neck cancer. Radiother Oncol 2011;101:376-82
48. Tuomikoski L, Collan J, Keyrilainen J, Visapaa H, Saarilahti K, Tenhunen M. Adaptive radiotherapy in muscle invasive urinary bladder cancer-An effective method to reduce the irradiated bowel volume. Radiother Oncol 2011;99:61-6
49. Murthy V, Master Z, Adurkar P, Mallick I, MahantshettYu, Bakshi G, et al. ' Plan of the day ' adaptive radiotherapy for bladder cancer using helical tomotherapy. Radiother Oncol 2011;99:55-60
50. Elstrom U V, Wysocka B A, Muren L P, Petersen J B, Grau C. Daily kV cone-beam CT and deformable image registration as a method for studying dosimetric consequences of anatomic changes in adaptive IMRT of head and neck cancer. Acta Oncol 2010;49:1101-8
51. Bertelsen A, Schytte T, Bentzen SM, Hansen O, Nielsen M, Brink C. Radiation dose response of normal lung assessed by cone beam CT-A potential tool for biologically adaptive radiation therapy. Radiother Oncol 2011;100:351-5
52. Lykkegaard Schmidt M. D osimetric impact of respiratory motion, interfraction baseline shifts, and anatomical changes in radiotherapy of non-small cell lung cancer. Acta Oncol 2013;(this issue
53. Verhaegen F. F irst clinical results of adaptive radiotherapy based on 3D portal dosimetry for lung cancer patients witHatelectasis treated with volumetric modulated arc therapy (VMAT). Acta Oncol 2013;(this issue
54. Vestergaard A, Sondergaard J, Petersen JB, Hoyer M, Muren LP. A comparison of three different adaptive strategies in image-guided radiotherapy of bladder cancer. Acta Oncol 2010;49:1069-76
55. Hoogeman M. A margin-of-the-day online-adaptive IMRT strategy for cervical cancer provides superior treatment accuracy compared to clinically recommended margins: A dosimetric evaluation. Acta Oncol 2013;(this issue
56. Tuomikoski L. Implementation of adaptive radiation therapy for urinary bladder carcinoma: Imaging, planning anDimage guidance. Acta Oncol 2013;(this issue
57. Wright P, RedpatHaT, Hoyer M, Muren LP. A method to individualize adaptive planning target volumes for deformable targets. Phys Med Biol 2009;54:7121-33
58. Potter R, Georg P, Dimopoulos JCA, Grimm M, Berger D, Nesvacil N, et al. ClinicaLoutcome of protocol baseDimage (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer. Radiother Oncol 2011;100:116-23
59. Tanderup K, Georg D, Potter R, Kirisits C, Grau C, Lindegaard JC. Adaptive management of cervical cancer radiotherapy. Semin Radiat Oncol 2010;20:121-9
60. Dimopoulos JCA, Petrow P, Tanderup K, Petric P, Berger D, Kirisits C, et al. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy. Radiother Oncol 2012;103:113-22
61. Lindegaard J. M RI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective. Acta Oncol 2013;(this issue
62. Hoeben B. MOlecular PET imaging for biology-guided adaptive radiotherapy of head and neck cancer. Acta Oncol 2013;(this issue
63. Carvalho S. P rognostic value of metabolic metrics extracted from baseline PET images in NSCLC. Acta Oncol 2013;(this issue