메뉴 건너뛰기




Volumn 19, Issue 18, 2013, Pages 5079-5091

Generation of tumor antigen-specific T cell lines from pediatric patients with acute lymphoblastic leukemia-implications for immunotherapy

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MELANOMA ANTIGEN 3; PRAME ANTIGEN; SURVIVIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG; WT1 PROTEIN;

EID: 84884573470     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-0955     Document Type: Article
Times cited : (61)

References (50)
  • 1
    • 53749084244 scopus 로고    scopus 로고
    • Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen
    • Kennedy-Nasser AA, Bollard CM, Myers GD, Leung KS, Gottschalk S, Zhang Y, et al. Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen. Biol Blood Marrow Transplant 2008;14:1245-52.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 1245-1252
    • Kennedy-Nasser, A.A.1    Bollard, C.M.2    Myers, G.D.3    Leung, K.S.4    Gottschalk, S.5    Zhang, Y.6
  • 2
    • 39149090347 scopus 로고    scopus 로고
    • Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system relapse: A collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research
    • Eapen M, Zhang MJ, Devidas M, Raetz E, Barredo JC, Ritchey AK, et al. Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system relapse: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research. Leukemia 2008;22:281-6.
    • (2008) Leukemia , vol.22 , pp. 281-286
    • Eapen, M.1    Zhang, M.J.2    Devidas, M.3    Raetz, E.4    Barredo, J.C.5    Ritchey, A.K.6
  • 3
    • 0029100438 scopus 로고
    • Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients
    • Kolb HJ, Schattenberg A, Goldman JM, Hertenstein B, Jacobsen N, Arcese W, et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood 1995;86:2041-50.
    • (1995) Blood , vol.86 , pp. 2041-2050
    • Kolb, H.J.1    Schattenberg, A.2    Goldman, J.M.3    Hertenstein, B.4    Jacobsen, N.5    Arcese, W.6
  • 4
    • 0028507899 scopus 로고
    • Donor mononuclear cell infusions as therapy for B-cell lymphoproliferative disorder following allogeneic bone marrow transplant
    • Porter DL, Orloff GJ, Antin JH. Donor mononuclear cell infusions as therapy for B-cell lymphoproliferative disorder following allogeneic bone marrow transplant. Transplant Sci 1994;4:12-4.
    • (1994) Transplant Sci , vol.4 , pp. 12-14
    • Porter, D.L.1    Orloff, G.J.2    Antin, J.H.3
  • 5
    • 84862127741 scopus 로고    scopus 로고
    • Absolute lymphocyte counts refine minimal residual disease-based risk stratification in childhood acute lymphoblastic leukemia
    • Rabin KR, Gramatges MM, Borowitz MJ, Palla SL, Shi X, Margolin JF, et al. Absolute lymphocyte counts refine minimal residual disease-based risk stratification in childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2012;59:468-74.
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 468-474
    • Rabin, K.R.1    Gramatges, M.M.2    Borowitz, M.J.3    Palla, S.L.4    Shi, X.5    Margolin, J.F.6
  • 6
    • 64049107901 scopus 로고    scopus 로고
    • Ex vivo characterization of polyclonal memory CD8+ T-cell responses to PRAME-specific peptides in patients with acute lymphoblastic leukemia and acute and chronic myeloid leukemia
    • Rezvani K, Yong AS, Tawab A, Jafarpour B, Eniafe R, Mielke S, et al. Ex vivo characterization of polyclonal memory CD8+ T-cell responses to PRAME-specific peptides in patients with acute lymphoblastic leukemia and acute and chronic myeloid leukemia. Blood 2009;113:2245-55.
    • (2009) Blood , vol.113 , pp. 2245-2255
    • Rezvani, K.1    Yong, A.S.2    Tawab, A.3    Jafarpour, B.4    Eniafe, R.5    Mielke, S.6
  • 7
    • 22744448681 scopus 로고    scopus 로고
    • Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: A prospective study
    • Choi SJ, Lee JH, Lee JH, Kim S, Lee YS, Seol M, et al. Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a prospective study. Bone Marrow Transplant 2005;36:163-9.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 163-169
    • Choi, S.J.1    Lee, J.H.2    Lee, J.H.3    Kim, S.4    Lee, Y.S.5    Seol, M.6
  • 8
    • 50049106424 scopus 로고    scopus 로고
    • Donor leukocyte infusions to treat hematologic malignancy relapse following allo-SCT in a pediatric population
    • Levine JE, Barrett AJ, Zhang MJ, Arora M, Pulsipher MA, Bunin N, et al. Donor leukocyte infusions to treat hematologic malignancy relapse following allo-SCT in a pediatric population. Bone Marrow Transplant 2008;42:201-5.
    • (2008) Bone Marrow Transplant , vol.42 , pp. 201-205
    • Levine, J.E.1    Barrett, A.J.2    Zhang, M.J.3    Arora, M.4    Pulsipher, M.A.5    Bunin, N.6
  • 10
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimericantigenreceptor-transduced T cells
    • Kochenderfer JN, Dudley ME, Feldman SA, Wilson WH, Spaner DE, Maric I, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimericantigenreceptor-transduced T cells. Blood 2012;119:2709-20.
    • (2012) Blood , vol.119 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3    Wilson, W.H.4    Spaner, D.E.5    Maric, I.6
  • 11
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 2011;121:1822-6.
    • (2011) J Clin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3    Mims, M.P.4    Keating, M.J.5    Carrum, G.6
  • 13
    • 34248148589 scopus 로고    scopus 로고
    • Transfer of PR1-specific T-cell clones from donor to recipient by stem cell transplantation and association with GvL activity
    • Rezvani K, Price DA, Brenchley JM, Kilical Y, Gostick E, Sconocchia G, et al. Transfer of PR1-specific T-cell clones from donor to recipient by stem cell transplantation and association with GvL activity. Cytotherapy 2007;9:245-51.
    • (2007) Cytotherapy , vol.9 , pp. 245-251
    • Rezvani, K.1    Price, D.A.2    Brenchley, J.M.3    Kilical, Y.4    Gostick, E.5    Sconocchia, G.6
  • 14
    • 38049188363 scopus 로고    scopus 로고
    • Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies
    • Rezvani K, Yong AS, Mielke S, Savani BN, Musse L, Superata J, et al. Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies. Blood 2008;111:236-42.
    • (2008) Blood , vol.111 , pp. 236-242
    • Rezvani, K.1    Yong, A.S.2    Mielke, S.3    Savani, B.N.4    Musse, L.5    Superata, J.6
  • 15
    • 84880259968 scopus 로고    scopus 로고
    • Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant
    • Weber G, Gerdemann U, Caruana I, Savoldo B, Hensel NF, Rabin KR, et al. Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant. Leukemia 2013;27:1538-47.
    • (2013) Leukemia , vol.27 , pp. 1538-1547
    • Weber, G.1    Gerdemann, U.2    Caruana, I.3    Savoldo, B.4    Hensel, N.F.5    Rabin, K.R.6
  • 16
    • 31444452790 scopus 로고    scopus 로고
    • Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: A wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring
    • Boublikova L, Kalinova M, Ryan J, Quinn F, O'Marcaigh A, Smith O, et al. Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring. Leukemia 2006;20:254-63.
    • (2006) Leukemia , vol.20 , pp. 254-263
    • Boublikova, L.1    Kalinova, M.2    Ryan, J.3    Quinn, F.4    O'Marcaigh, A.5    Smith, O.6
  • 17
    • 0030746636 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
    • Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997;3:917-21.
    • (1997) Nat Med , vol.3 , pp. 917-921
    • Ambrosini, G.1    Adida, C.2    Altieri, D.C.3
  • 21
    • 9044226139 scopus 로고    scopus 로고
    • Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia
    • Smith M, Arthur D, Camitta B, Carroll AJ, Crist W, Gaynon P, et al. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol 1996;14:18-24.
    • (1996) J Clin Oncol , vol.14 , pp. 18-24
    • Smith, M.1    Arthur, D.2    Camitta, B.3    Carroll, A.J.4    Crist, W.5    Gaynon, P.6
  • 22
    • 82955219544 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma
    • Gerdemann U, Katari U, Christin AS, Cruz CR, Tripic T, Rousseau A, et al. Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma. Mol Ther 2011;19:2258-68.
    • (2011) Mol Ther , vol.19 , pp. 2258-2268
    • Gerdemann, U.1    Katari, U.2    Christin, A.S.3    Cruz, C.R.4    Tripic, T.5    Rousseau, A.6
  • 23
    • 70349306860 scopus 로고    scopus 로고
    • WT1 peptide-specific T cells generated from peripheral blood of healthy donors: Possible implications for adoptive immunotherapy after allogeneic stem cell transplantation
    • Weber G, Karbach J, Kuci S, Kreyenberg H, Willasch A, Koscielniak E, et al. WT1 peptide-specific T cells generated from peripheral blood of healthy donors: possible implications for adoptive immunotherapy after allogeneic stem cell transplantation. Leukemia 2009;23:1634-42.
    • (2009) Leukemia , vol.23 , pp. 1634-1642
    • Weber, G.1    Karbach, J.2    Kuci, S.3    Kreyenberg, H.4    Willasch, A.5    Koscielniak, E.6
  • 24
    • 84865403847 scopus 로고    scopus 로고
    • Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1 (+) leukemias
    • Doubrovina E, Carpenter T, Pankov D, Selvakumar A, Hasan A, O'Reilly RJ. Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1 (+) leukemias. Blood 2012;120:1633-46.
    • (2012) Blood , vol.120 , pp. 1633-1646
    • Doubrovina, E.1    Carpenter, T.2    Pankov, D.3    Selvakumar, A.4    Hasan, A.5    O'Reilly, R.J.6
  • 26
    • 0033966369 scopus 로고    scopus 로고
    • HLA class I-restricted lysis of leukemia cells by a CD8 (+) cytotoxic T-lymphocyte clone specific for WT1 peptide
    • Ohminami H, Yasukawa M, Fujita S. HLA class I-restricted lysis of leukemia cells by a CD8 (+) cytotoxic T-lymphocyte clone specific for WT1 peptide. Blood 2000;95:286-93.
    • (2000) Blood , vol.95 , pp. 286-293
    • Ohminami, H.1    Yasukawa, M.2    Fujita, S.3
  • 27
    • 29344436442 scopus 로고    scopus 로고
    • T-cell responses directed against multiple HLA-A 0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: Identification, quantification, and characterization
    • Rezvani K, Brenchley JM, Price DA, Kilical Y, Gostick E, Sewell AK, et al. T-cell responses directed against multiple HLA-A 0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization. Clin Cancer Res 2005;11(24 Pt 1):8799-807.
    • (2005) Clin Cancer Res , vol.11 , Issue.24 PART 1 , pp. 8799-8807
    • Rezvani, K.1    Brenchley, J.M.2    Price, D.A.3    Kilical, Y.4    Gostick, E.5    Sewell, A.K.6
  • 28
    • 34347398235 scopus 로고    scopus 로고
    • Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities
    • Wolfl M, Kuball J, Ho WY, Nguyen H, Manley TJ, Bleakley M, et al. Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities. Blood 2007;110:201-10.
    • (2007) Blood , vol.110 , pp. 201-210
    • Wolfl, M.1    Kuball, J.2    Ho, W.Y.3    Nguyen, H.4    Manley, T.J.5    Bleakley, M.6
  • 29
    • 0032850575 scopus 로고    scopus 로고
    • Target structures of the CD8 (+)-T-cell response to human cytomegalovirus: The 72-kilodalton major immediate-early protein revisited
    • Kern F, Surel IP, Faulhaber N, Frommel C, Schneider-Mergener J, Schonemann C, et al. Target structures of the CD8 (+)-T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited. J Virol 1999;73:8179-84.
    • (1999) J Virol , vol.73 , pp. 8179-8184
    • Kern, F.1    Surel, I.P.2    Faulhaber, N.3    Frommel, C.4    Schneider-Mergener, J.5    Schonemann, C.6
  • 30
    • 76949100884 scopus 로고    scopus 로고
    • Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex)
    • Vera JF, Brenner LJ, Gerdemann U, Ngo MC, Sili U, Liu H, et al. Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex). J Immunother 2010;33:305-15.
    • (2010) J Immunother , vol.33 , pp. 305-315
    • Vera, J.F.1    Brenner, L.J.2    Gerdemann, U.3    Ngo, M.C.4    Sili, U.5    Liu, H.6
  • 31
    • 70350458112 scopus 로고    scopus 로고
    • Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity
    • Hinrichs CS, Borman ZA, Cassard L, Gattinoni L, Spolski R, Yu Z, et al. Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity. Proc Natl Acad Sci U S A 2009;106:17469-74.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 17469-17474
    • Hinrichs, C.S.1    Borman, Z.A.2    Cassard, L.3    Gattinoni, L.4    Spolski, R.5    Yu, Z.6
  • 32
    • 78751689288 scopus 로고    scopus 로고
    • Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy
    • Hinrichs CS, Borman ZA, Gattinoni L, Yu Z, Burns WR, Huang J, et al. Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy. Blood 2011;117:808-14.
    • (2011) Blood , vol.117 , pp. 808-814
    • Hinrichs, C.S.1    Borman, Z.A.2    Gattinoni, L.3    Yu, Z.4    Burns, W.R.5    Huang, J.6
  • 33
    • 70349247010 scopus 로고    scopus 로고
    • Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes
    • Hanley PJ, Cruz CR, Savoldo B, Leen AM, Stanojevic M, Khalil M, et al. Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes. Blood 2009;114:1958-67.
    • (2009) Blood , vol.114 , pp. 1958-1967
    • Hanley, P.J.1    Cruz, C.R.2    Savoldo, B.3    Leen, A.M.4    Stanojevic, M.5    Khalil, M.6
  • 34
    • 52649135956 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia
    • Quintarelli C, Dotti G, De AB, Hoyos V, Mims M, Luciano L, et al. Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia. Blood 2008;112:1876-85.
    • (2008) Blood , vol.112 , pp. 1876-1885
    • Quintarelli, C.1    Dotti, G.2    De, A.B.3    Hoyos, V.4    Mims, M.5    Luciano, L.6
  • 35
    • 84862757086 scopus 로고    scopus 로고
    • Lymphodepletion is permissive to the development of spontaneous Tcell responses to the self-antigen PR1 early after allogeneic stem cell transplantation and in patients with acute myeloid leukemia undergoing WT1 peptide vaccination following chemotherapy
    • Rezvani K, Yong AS, Mielke S, Savani BN, Jafarpour B, Eniafe R, et al. Lymphodepletion is permissive to the development of spontaneous Tcell responses to the self-antigen PR1 early after allogeneic stem cell transplantation and in patients with acute myeloid leukemia undergoing WT1 peptide vaccination following chemotherapy. Cancer Immunol Immunother 2012;61:1125-36.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 1125-1136
    • Rezvani, K.1    Yong, A.S.2    Mielke, S.3    Savani, B.N.4    Jafarpour, B.5    Eniafe, R.6
  • 36
    • 77649221824 scopus 로고    scopus 로고
    • Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
    • Heslop HE, Slobod KS, Pule MA, Hale GA, Rousseau A, Smith CA, et al. Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients. Blood 2010;115:925-35.
    • (2010) Blood , vol.115 , pp. 925-935
    • Heslop, H.E.1    Slobod, K.S.2    Pule, M.A.3    Hale, G.A.4    Rousseau, A.5    Smith, C.A.6
  • 37
    • 33749514632 scopus 로고    scopus 로고
    • Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
    • Leen AM, Myers GD, Sili U, Huls MH, Weiss H, Leung KS, et al. Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals. Nat Med 2006;12:1160-6.
    • (2006) Nat Med , vol.12 , pp. 1160-1166
    • Leen, A.M.1    Myers, G.D.2    Sili, U.3    Huls, M.H.4    Weiss, H.5    Leung, K.S.6
  • 38
    • 77956924038 scopus 로고    scopus 로고
    • Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia
    • Goodyear O, Agathanggelou A, Novitzky-Basso I, Siddique S, McSkeane T, Ryan G, et al. Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia. Blood 2010;116:1908-18.
    • (2010) Blood , vol.116 , pp. 1908-1918
    • Goodyear, O.1    Agathanggelou, A.2    Novitzky-Basso, I.3    Siddique, S.4    McSkeane, T.5    Ryan, G.6
  • 39
    • 84861904198 scopus 로고    scopus 로고
    • Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia
    • Bhatla T, Wang J, Morrison DJ, Raetz EA, Burke MJ, Brown P, et al. Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia. Blood 2012;119:5201-10.
    • (2012) Blood , vol.119 , pp. 5201-5210
    • Bhatla, T.1    Wang, J.2    Morrison, D.J.3    Raetz, E.A.4    Burke, M.J.5    Brown, P.6
  • 40
    • 81255143446 scopus 로고    scopus 로고
    • Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4
    • Cruz CR, Gerdemann U, Leen AM, Shafer JA, Ku S, Tzou B, et al. Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4. Clin Cancer Res 2011;17:7058-66.
    • (2011) Clin Cancer Res , vol.17 , pp. 7058-7066
    • Cruz, C.R.1    Gerdemann, U.2    Leen, A.M.3    Shafer, J.A.4    Ku, S.5    Tzou, B.6
  • 41
    • 78651290248 scopus 로고    scopus 로고
    • Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia
    • Handgretinger R, Zugmaier G, Henze G, Kreyenberg H, Lang P, von SA. Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia. Leukemia 2011;25:181-4.
    • (2011) Leukemia , vol.25 , pp. 181-184
    • Handgretinger, R.1    Zugmaier, G.2    Henze, G.3    Kreyenberg, H.4    Lang, P.5    Von, S.A.6
  • 42
    • 79959312575 scopus 로고    scopus 로고
    • Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in Blineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
    • Topp MS, Kufer P, Gokbuget N, Goebeler M, Klinger M, Neumann S, et al. Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in Blineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol 2011;29:2493-8.
    • (2011) J Clin Oncol , vol.29 , pp. 2493-2498
    • Topp, M.S.1    Kufer, P.2    Gokbuget, N.3    Goebeler, M.4    Klinger, M.5    Neumann, S.6
  • 43
    • 69249220181 scopus 로고    scopus 로고
    • A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS
    • Keilholz U, Letsch A, Busse A, Asemissen AM, Bauer S, Blau IW, et al. A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS. Blood 2009;113:6541-8.
    • (2009) Blood , vol.113 , pp. 6541-6548
    • Keilholz, U.1    Letsch, A.2    Busse, A.3    Asemissen, A.M.4    Bauer, S.5    Blau, I.W.6
  • 45
    • 0034541167 scopus 로고    scopus 로고
    • Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity
    • Marzo AL, Kinnear BF, Lake RA, Frelinger JJ, Collins EJ, Robinson BW, et al. Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity. J Immunol 2000;165:6047-55.
    • (2000) J Immunol , vol.165 , pp. 6047-6055
    • Marzo, A.L.1    Kinnear, B.F.2    Lake, R.A.3    Frelinger, J.J.4    Collins, E.J.5    Robinson, B.W.6
  • 46
    • 77955481538 scopus 로고    scopus 로고
    • Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia
    • Maslak PG, Dao T, Krug LM, Chanel S, Korontsvit T, Zakhaleva V, et al. Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia. Blood 2010;116:171-9.
    • (2010) Blood , vol.116 , pp. 171-179
    • Maslak, P.G.1    Dao, T.2    Krug, L.M.3    Chanel, S.4    Korontsvit, T.5    Zakhaleva, V.6
  • 47
    • 23744460167 scopus 로고    scopus 로고
    • Direct recognition and lysis of leukemia cells by WT1-specific CD4+ T lymphocytes in an HLA class II-restricted manner
    • Guo Y, Niiya H, Azuma T, Uchida N, Yakushijin Y, Sakai I, et al. Direct recognition and lysis of leukemia cells by WT1-specific CD4+ T lymphocytes in an HLA class II-restricted manner. Blood 2005;106:1415-8.
    • (2005) Blood , vol.106 , pp. 1415-1418
    • Guo, Y.1    Niiya, H.2    Azuma, T.3    Uchida, N.4    Yakushijin, Y.5    Sakai, I.6
  • 48
    • 22144439081 scopus 로고    scopus 로고
    • Tumor antigen-specific T helper cells in cancer immunity and immunotherapy
    • Knutson KL, Disis ML. Tumor antigen-specific T helper cells in cancer immunity and immunotherapy. Cancer Immunol Immunother 2005;54:721-8.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 721-728
    • Knutson, K.L.1    Disis, M.L.2
  • 49
    • 0034176750 scopus 로고    scopus 로고
    • Selective elimination of leukemic CD34 (+) progenitor cells by cytotoxic T lymphocytes specific for WT1
    • Gao L, Bellantuono I, Elsasser A, Marley SB, Gordon MY, Goldman JM, et al. Selective elimination of leukemic CD34 (+) progenitor cells by cytotoxic T lymphocytes specific for WT1. Blood 2000;95:2198-203.
    • (2000) Blood , vol.95 , pp. 2198-2203
    • Gao, L.1    Bellantuono, I.2    Elsasser, A.3    Marley, S.B.4    Gordon, M.Y.5    Goldman, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.