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Volumn 19, Issue 8, 2013, Pages 1662-1670

Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease

(22)  Dubinsky, Marla C a   Kugathasan, Subra b   Kwon, Soonil c   Haritunians, Talin c   Wrobel, Iwona d   Wahbeh, Ghassan e   Quiros, Antonio f   Bahar, Ron a   Silber, Gary g   Farrior, Sharmayne a   Stephens, Michael h   Teleten, Nick c   Panikkath, Deepa c   Ippoliti, Andrew c   Vasiliauskas, Eric c   Fleshner, Phillip c   Williams, Chadwick c   Landers, Carol c   Rotter, Jerome I c   Targan, Stephan R c   more..


Author keywords

Biomarkers; Complications of IBD; Genotype clinical phenotype; Surgery for IBD

Indexed keywords

INTERLEUKIN 12P40;

EID: 84884560070     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0b013e318281f275     Document Type: Article
Times cited : (30)

References (34)
  • 1
    • 0036061640 scopus 로고    scopus 로고
    • Long-term evolution of disease behavior of Crohn's disease
    • Cosnes J, Cattan S, Blain A, et al. Long-term evolution of disease behavior of Crohn's disease. Inflamm Bowel Dis. 2002;8:244-250.
    • (2002) Inflamm Bowel Dis , vol.8 , pp. 244-250
    • Cosnes, J.1    Cattan, S.2    Blain, A.3
  • 2
    • 12344291265 scopus 로고    scopus 로고
    • Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery
    • Cosnes J, Nion-Larmurier I, Beaugerie L, et al. Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery. Gut. 2005;54:237-241.
    • (2005) Gut , vol.54 , pp. 237-241
    • Cosnes, J.1    Nion-Larmurier, I.2    Beaugerie, L.3
  • 4
    • 33644908022 scopus 로고    scopus 로고
    • Serum immune responses predict rapid disease progression among children with Crohn's disease: Immune responses predict disease progression
    • Dubinsky MC, Lin YC, Dutridge D, et al. Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression. Am J Gastroenterol. 2006;101:360-367.
    • (2006) Am J Gastroenterol , vol.101 , pp. 360-367
    • Dubinsky, M.C.1    Lin, Y.C.2    Dutridge, D.3
  • 5
    • 52949145981 scopus 로고    scopus 로고
    • Increased immune reactivity predicts aggressive complicating Crohn's disease in children
    • Dubinsky MC, Kugathasan S, Mei L, et al. Increased immune reactivity predicts aggressive complicating Crohn's disease in children. Clin Gastro Hep. 2008;6:1105-1111.
    • (2008) Clin Gastro Hep , vol.6 , pp. 1105-1111
    • Dubinsky, M.C.1    Kugathasan, S.2    Mei, L.3
  • 6
    • 40949094473 scopus 로고    scopus 로고
    • New serological markers for inflammatory bowel disease are associated with earlier age at onset, complicated disease behavior, risk for surgery, and NOD2/CARD15 genotype in a Hungarian IBD cohort
    • Papp M, Altorjay I, Dotan N, et al. New serological markers for inflammatory bowel disease are associated with earlier age at onset, complicated disease behavior, risk for surgery, and NOD2/CARD15 genotype in a Hungarian IBD cohort. Am J Gastroenterol. 2008;103:665-681.
    • (2008) Am J Gastroenterol , vol.103 , pp. 665-681
    • Papp, M.1    Altorjay, I.2    Dotan, N.3
  • 7
    • 34948854194 scopus 로고    scopus 로고
    • New serological markers in inflammatory bowel disease are associated with complicated disease behavior
    • Ferrante M, Henckaerts L, Joossens M, et al. New serological markers in inflammatory bowel disease are associated with complicated disease behavior. Gut. 2007;56:1394-1403.
    • (2007) Gut , vol.56 , pp. 1394-1403
    • Ferrante, M.1    Henckaerts, L.2    Joossens, M.3
  • 8
    • 9144228789 scopus 로고    scopus 로고
    • Risk of early surgery for Crohn's disease: Implications for early treatment strategies
    • Sands BE, Arsenault JE, Rosen MJ, et al. Risk of early surgery for Crohn's disease: implications for early treatment strategies. Am J Gastroenterol. 2003;98:2712-2718.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2712-2718
    • Sands, B.E.1    Arsenault, J.E.2    Rosen, M.J.3
  • 9
    • 33644755927 scopus 로고    scopus 로고
    • Utility of serological markers in predicting the early occurrence of complications and surgery in pediatric Crohn's disease patients
    • Amre DK, Lu SE, Costea F, et al. Utility of serological markers in predicting the early occurrence of complications and surgery in pediatric Crohn's disease patients. Am J Gastroenterol. 2006;101:645-652.
    • (2006) Am J Gastroenterol , vol.101 , pp. 645-652
    • Amre, D.K.1    Lu, S.E.2    Costea, F.3
  • 10
    • 10744228695 scopus 로고    scopus 로고
    • Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease
    • Mow WS, Vasiliauskas EA, Lin YC, et al. Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. Gastroenterology. 2004;126:414-424.
    • (2004) Gastroenterology , vol.126 , pp. 414-424
    • Mow, W.S.1    Vasiliauskas, E.A.2    Lin, Y.C.3
  • 11
    • 11144266571 scopus 로고    scopus 로고
    • Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype
    • Arnott ID, Landers CJ, Nimmo EJ, et al. Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype. Am J Gastroenterol. 2004;99:2376-2384.
    • (2004) Am J Gastroenterol , vol.99 , pp. 2376-2384
    • Arnott, I.D.1    Landers, C.J.2    Nimmo, E.J.3
  • 12
    • 78650077217 scopus 로고    scopus 로고
    • A real-time tool to display the predicted disease course and treatment response for children with Crohn's disease
    • Siegel CA, Siegel LS, Hyams JS, et al. A real-time tool to display the predicted disease course and treatment response for children with Crohn's disease. Inflamm Bowel Dis. 2011;17:30-38.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 30-38
    • Siegel, C.A.1    Siegel, L.S.2    Hyams, J.S.3
  • 13
    • 0036201577 scopus 로고    scopus 로고
    • CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
    • Lesage S, Zouali H, Cezard JP, et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet. 2002;70:845-857.
    • (2002) Am J Hum Genet , vol.70 , pp. 845-857
    • Lesage, S.1    Zouali, H.2    Cezard, J.P.3
  • 14
    • 0036725827 scopus 로고    scopus 로고
    • Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
    • Abreu MT, Taylor KD, Lin YC, et al. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease. Gastroenterology. 2002;123:679-688.
    • (2002) Gastroenterology , vol.123 , pp. 679-688
    • Abreu, M.T.1    Taylor, K.D.2    Lin, Y.C.3
  • 15
    • 9144271221 scopus 로고    scopus 로고
    • L1007Fsinc variant of CARD15/NOD2 is strongly associated with early onset and fibrostenosing behavior in pediatric Crohn's disease
    • Kugathasan S, Maresso K, Collins N, et al. L1007Fsinc variant of CARD15/NOD2 is strongly associated with early onset and fibrostenosing behavior in pediatric Crohn's disease. Clin Gastroenterol Hepatol. 2004;2:1003-1009.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 1003-1009
    • Kugathasan, S.1    Maresso, K.2    Collins, N.3
  • 16
    • 27644591952 scopus 로고    scopus 로고
    • Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease
    • Russell RK, Drummond HE, Nimmo EE, et al. Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease. Inflamm Bowel Dis. 2005;11:955-964.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 955-964
    • Russell, R.K.1    Drummond, H.E.2    Nimmo, E.E.3
  • 17
    • 27644562698 scopus 로고    scopus 로고
    • Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence
    • Alvarez-Lobos M, Arostegui JI, Sans M, et al. Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence. Ann Surg. 2005; 242:693-700.
    • (2005) Ann Surg , vol.242 , pp. 693-700
    • Alvarez-Lobos, M.1    Arostegui, J.I.2    Sans, M.3
  • 18
    • 33751561942 scopus 로고    scopus 로고
    • Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: Results of a prospective study
    • Seiderer J, Brand S, Herrmann KA, et al. Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study. Inflamm Bowel Dis. 2006;12:1114-1121.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1114-1121
    • Seiderer, J.1    Brand, S.2    Herrmann, K.A.3
  • 19
    • 69249152654 scopus 로고    scopus 로고
    • Genetic risk profiling and prediction of disease course in Crohn's disease patients
    • Henckaerts L, Van Steen K, Verstreken I, et al. Genetic risk profiling and prediction of disease course in Crohn's disease patients. Clin Gastro Hep. 2009;7:972-980.
    • (2009) Clin Gastro Hep , vol.7 , pp. 972-980
    • Henckaerts, L.1    Van Steen, K.2    Verstreken, I.3
  • 20
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
    • Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010;42:1118-1125.
    • (2010) Nat Genet , vol.42 , pp. 1118-1125
    • Franke, A.1    McGovern, D.P.2    Barrett, J.C.3
  • 21
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    • Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008;40:955-962.
    • (2008) Nat Genet , vol.40 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3
  • 22
    • 77955398591 scopus 로고    scopus 로고
    • Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    • McGovern DP, Jones MR, Taylor KD, et al. Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. Hum Mol Genet. 2010;19: 3468-3476.
    • (2010) Hum Mol Genet , vol.19 , pp. 3468-3476
    • McGovern, D.P.1    Jones, M.R.2    Taylor, K.D.3
  • 23
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert H, König IR, Kathiresan S, et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011;43:333-338.
    • (2011) Nat Genet , vol.43 , pp. 333-338
    • Schunkert, H.1    König, I.R.2    Kathiresan, S.3
  • 24
    • 78049429252 scopus 로고    scopus 로고
    • Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: The cardiovascular risk in young Finns study
    • Okser S, Lehtimäki T, Elo LL, et al. Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study. PLoS Genet. 2010;30:6.
    • (2010) PLoS Genet , vol.30 , pp. 6
    • Okser, S.1    Lehtimäki, T.2    Elo, L.L.3
  • 25
    • 20444441016 scopus 로고    scopus 로고
    • Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease
    • Targan SR, Landers CJ, Yang H, et al. Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology. 2005;128:2020-2028.
    • (2005) Gastroenterology , vol.128 , pp. 2020-2028
    • Targan, S.R.1    Landers, C.J.2    Yang, H.3
  • 26
    • 0033805362 scopus 로고    scopus 로고
    • Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics
    • Vasiliauskas EA, Kam LY, Karp LC, et al. Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics. Gut. 2000;47:487-496.
    • (2000) Gut , vol.47 , pp. 487-496
    • Vasiliauskas, E.A.1    Kam, L.Y.2    Karp, L.C.3
  • 27
    • 18144425478 scopus 로고    scopus 로고
    • A genome-wide scalable SNP genotyping assay using microarray technology
    • Gunderson KL, Steemers FJ, Lee G, et al. A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet. 2005;37:549-554.
    • (2005) Nat Genet , vol.37 , pp. 549-554
    • Gunderson, K.L.1    Steemers, F.J.2    Lee, G.3
  • 28
    • 0032866127 scopus 로고    scopus 로고
    • High-throughput single nucleotide polymorphism genotyping by fluorescent 5' exonuclease assay
    • Morin PA, Saiz R, Monjazeb A. High-throughput single nucleotide polymorphism genotyping by fluorescent 5' exonuclease assay. Biotechniques. 1999;27:538-552.
    • (1999) Biotechniques , vol.27 , pp. 538-552
    • Morin, P.A.1    Saiz, R.2    Monjazeb, A.3
  • 29
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38:904-909.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3
  • 31
    • 67650255063 scopus 로고    scopus 로고
    • Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
    • McGovern DP, Rotter JI, Mei L, et al. Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease. Inflamm Bowel Dis. 2009;15:883-889.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 883-889
    • McGovern, D.P.1    Rotter, J.I.2    Mei, L.3
  • 32
    • 61549115034 scopus 로고    scopus 로고
    • Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn disease
    • Wang K, Zhang H, Kugathasan S, et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn disease. Am J Hum Genet. 2009;84:399-405.
    • (2009) Am J Hum Genet , vol.84 , pp. 399-405
    • Wang, K.1    Zhang, H.2    Kugathasan, S.3
  • 33
    • 78249287838 scopus 로고    scopus 로고
    • Genetic predictors of medically refractory ulcerative colitis
    • Haritunians T, Taylor KD, Targan SR, et al. Genetic predictors of medically refractory ulcerative colitis. Inflamm Bowel Dis. 2010;16:1830-1840.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1830-1840
    • Haritunians, T.1    Taylor, K.D.2    Targan, S.R.3
  • 34
    • 0037473104 scopus 로고    scopus 로고
    • CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity
    • Carboni GL, Gao B, Nishizaki M, et al. CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity. Oncogene. 2003;22:615-626.
    • (2003) Oncogene , vol.22 , pp. 615-626
    • Carboni, G.L.1    Gao, B.2    Nishizaki, M.3


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